scholarly journals Novel 3D-printed prosthetic composite for reconstruction of massive bone defects in lower extremities after malignant tumor resection

2019 ◽  
Vol 16 ◽  
pp. 100220 ◽  
Author(s):  
Yajie Lu ◽  
Guojing Chen ◽  
Zuoyao Long ◽  
Minghui Li ◽  
Chuanlei Ji ◽  
...  
Keyword(s):  
Malignant Tumor ◽  
Tumor Resection ◽  
Lower Extremities ◽  
Bone Defects ◽  
3D Printed ◽  
Massive Bone

Modified Classification and Single-Stage Microsurgical Repair of Posttraumatic Infected Massive Bone Defects in Lower Extremities

2013 ◽  
Vol 29 (09) ◽  
pp. 593-600 ◽  
Author(s):  
Yun-fa Yang ◽  
Zhong-he Xu ◽  
Guang-ming Zhang ◽  
Jian-wei Wang ◽  
Si-wang Hu ◽  
...  
Keyword(s):  
Lower Extremities ◽  
Bone Defects ◽  
Single Stage ◽  
Massive Bone

3D-printed magnetic Fe3O4/MBG/PCL composite scaffolds with multifunctionality of bone regeneration, local anticancer drug delivery and hyperthermia

2014 ◽  
Vol 2 (43) ◽  
pp. 7583-7595 ◽  
Author(s):  
Jianhua Zhang ◽  
Shichang Zhao ◽  
Min Zhu ◽  
Yufang Zhu ◽  
Yadong Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Bone Regeneration ◽  
Tumor Resection ◽  
Bone Defects ◽  
Composite Scaffolds ◽  
Anticancer Drug Delivery ◽  
3D Printed ◽  
Large Bone ◽  
Large Bone Defects ◽  
Magnetic Fe3o4

The 3D-printed Fe3O4/MBG/PCL scaffolds with potential multifunctionality would be promising for use in the treatment and regeneration of large bone defects after tumor resection.

scholarly journals Reconstruction of Total Bone Defects following Resection of Malignant Tumors of the Upper Extremity with 3D Printed Prostheses: Presentation of Two Patients with a Follow-Up of Three Years

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Thomas Ackmann ◽  
Sebastian Klingebiel ◽  
Georg Gosheger ◽  
Anna Rachbauer ◽  
Christoph Theil ◽  
...  
Keyword(s):  
Upper Extremity ◽  
Bone Tumors ◽  
Malignant Tumors ◽  
Local Treatment ◽  
Tumor Resection ◽  
Bone Defects ◽  
Malignant Bone Tumors ◽  
Term Survival ◽  
First Case ◽  
3D Printed

Wide tumor resection is the local treatment of choice for patients with primary malignant bone tumors and a prerequisite for long-term survival. We present two patients that underwent total bone resection in the upper limb because of primary malignant bone tumors. The defects were then reconstructed by a 3D printed prosthesis, a procedure that, to our knowledge, has not been reported for bone defects of the upper extremity so far. Complete resection of the affected bone was required in a five-year-old girl with a high-grade osteoblastic osteosarcoma of the humerus and a 53-year-old man with a dedifferentiated leiomyosarcoma of the radius, due to the tumor’s extent. Following neoadjuvant chemotherapy, resection of the entire affected humerus including the axillary nerve took place in the first case and the entire affected radius including parts of the radial nerve in the second case. Approximately three years after surgery, both patients are alive and pain-free. Despite a postoperative drop hand that affected the now 56-year-old man, he is able to carry out everyday activities such as brushing his teeth, writing, and eating. The now eight-year-old girl is also able to engage in normal activities with her left arm such as eating and carrying lightweight objects. Both patients are tumor-free to date.

A 3D-Printed Model-Assisted Cervical Spine Instrumentation after Tumor Resection in a 4-Year-Old Child: A Case Report

2021 ◽  
pp. 1-7
Author(s):  
Marko Jug
Keyword(s):  
Cervical Spine ◽  
3D Model ◽  
Intraoperative Complications ◽  
Tumor Resection ◽  
Upper Cervical Spine ◽  
Spine Instrumentation ◽  
Cord Injury ◽  
Spinal Navigation ◽  
Upper Cervical ◽  
3D Printed

<b><i>Introduction:</i></b> In the case of tumor resection in the upper cervical spine, a multilevel laminectomy with instrumented fixation is required to prevent kyphotic deformity and myelopathy. Nevertheless, instrumentation of the cervical spine in children under the age of 8 years is challenging due to anatomical considerations and unavailability of specific instrumentation. <b><i>Case Presentation:</i></b> We present a case of 3D-printed model-assisted cervical spine instrumentation in a 4-year-old child with post-laminectomy kyphotic decompensation of the cervical spine and spinal cord injury 1 year after medulloblastoma metastasis resection in the upper cervical spine. Due to unavailability of specific instrumentation, 3D virtual planning was used to assess and plan posterior cervical fixation. Fixation with 3.5 mm lateral mass and isthmic screws was suggested and the feasibility of fixation was confirmed “in vitro” in a 3D-printed model preoperatively to reduce the possibility of intraoperative implant-spine mismatch. Intraoperative conditions completely resembled the preoperative plan and 3.5 mm polyaxial screws were successfully used as planned. Postoperatively the child made a complete neurological recovery and 2 years after the instrumented fusion is still disease free with no signs of spinal decompensation. <b><i>Discussion/Conclusion:</i></b> Our case shows that posterior cervical fixation with the conventional screw-rod technique in a 4-year-old child is feasible, but we suggest that suitability and positioning of the chosen implants are preoperatively assessed in a printed 3D model. In addition, a printed 3D model offers the possibility to better visualize and sense spinal anatomy “in vivo,” thereby helping screw placement and reducing the chance for intraoperative complications, especially in the absence of intraoperative spinal navigation.

scholarly journals Clinical study of 3D printed personalized prosthesis in the treatment of bone defect after pelvic tumor resection

2021 ◽  
Vol 29 ◽  
pp. 163-169
Author(s):  
Lin Xu ◽  
Hao Qin ◽  
Jia Tan ◽  
Zhilin Cheng ◽  
Xiang Luo ◽  
...  
Keyword(s):  
Clinical Study ◽  
Bone Defect ◽  
Tumor Resection ◽  
Pelvic Tumor ◽  
3D Printed

Scaffold 3D‐Printed from Metallic Nanoparticles‐Containing Ink Simultaneously Eradicates Tumor and Repairs Tumor‐Associated Bone Defects

Small Methods ◽  
2021 ◽  
pp. 2100536
Author(s):  
Huimin Lin ◽  
Shanwei Shi ◽  
Xinyue Lan ◽  
Xiaolong Quan ◽  
Qinqin Xu ◽  
...  
Keyword(s):  
Metallic Nanoparticles ◽  
Bone Defects ◽  
3D Printed

Therapy and regeneration-combined bone cements for minimally invasive treatment of neoplastic bone defects

2021 ◽  
Author(s):  
Yu Qu ◽  
Hui Zhuang ◽  
Meng Zhang ◽  
Yufeng Wang ◽  
Dong Zhai ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Minimally Invasive ◽  
Tumor Cells ◽  
Bone Tumor ◽  
Tumor Resection ◽  
Bone Defects ◽  
Bone Cements ◽  
Invasive Treatment ◽  
Calcium Phosphate Cements ◽  
Bone Tumor Resection

Although calcium phosphate cements (CPC) have been clinically used to repair bone defects caused by bone tumor resection, traditional CPC cannot kill the remaining tumor cells after surgery and prevent...

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