Equilibrium sampling through membrane based on a single hollow fibre for determination of drug–protein binding and free drug concentration in plasma

Tatjana Trtić-Petrović; Jing-Fu Liu; Jan Åke Jönsson

doi:10.1016/j.jchromb.2005.08.020

Equilibrium sampling through membrane based on a single hollow fibre for determination of drug–protein binding and free drug concentration in plasma

Journal of Chromatography B ◽

10.1016/j.jchromb.2005.08.020 ◽

2005 ◽

Vol 826 (1-2) ◽

pp. 169-176 ◽

Cited By ~ 21

Author(s):

Tatjana Trtić-Petrović ◽

Jing-Fu Liu ◽

Jan Åke Jönsson

Keyword(s):

Protein Binding ◽

Drug Concentration ◽

Hollow Fibre ◽

Free Drug ◽

Free Drug Concentration ◽

Drug Protein Binding

Download Full-text

High-performance frontal analysis for the determination of the free drug concentration in protein binding equilibrium using porous polymer stationary phase.

Analytical Sciences ◽

10.2116/analsci.6.355 ◽

1990 ◽

Vol 6 (3) ◽

pp. 355-359 ◽

Cited By ~ 23

Author(s):

Naohiro NISHIMURA ◽

Akimasa SHIBUKAWA ◽

Terumichi NAKAGAWA

Keyword(s):

Protein Binding ◽

Stationary Phase ◽

Drug Concentration ◽

High Performance ◽

Free Drug ◽

Porous Polymer ◽

Frontal Analysis ◽

Free Drug Concentration

Download Full-text

Determination of Fraction Unbound and Unbound Partition Coefficient to Estimate Intracellular Free Drug Concentration

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_4 ◽

2021 ◽

pp. 81-96

Author(s):

Sangwoo Ryu ◽

Keith Riccardi ◽

Samantha Jordan ◽

Nathaniel Johnson ◽

Li Di

Keyword(s):

Partition Coefficient ◽

Drug Concentration ◽

Free Drug ◽

Free Drug Concentration

Download Full-text

The P-glycoprotein-mediated relative decrease in cytosolic free drug concentration is similar for several anthracyclines with varying lipophilicity

Biochemical Pharmacology ◽

10.1016/0006-2952(95)00221-k ◽

1995 ◽

Vol 50 (7) ◽

pp. 967-974 ◽

Cited By ~ 21

Author(s):

H.Sipko Mülder ◽

Henk Dekker ◽

Herbert M. Pinedo ◽

Jan Lankelma

Keyword(s):

Drug Concentration ◽

Free Drug ◽

Free Drug Concentration ◽

P Glycoprotein ◽

Relative Decrease

Download Full-text

Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice

International Journal of Pharmaceutics ◽

10.1016/s0378-5173(02)00705-6 ◽

2003 ◽

Vol 253 (1-2) ◽

pp. 159-168 ◽

Cited By ~ 19

Author(s):

Mohsen I Afouna ◽

Timothy K Fincher ◽

Abdel-Azim A Zaghloul ◽

Indra K Reddy

Keyword(s):

Drug Concentration ◽

Free Drug ◽

Target Site ◽

Free Drug Concentration ◽

Hairless Mice ◽

Topical Formulations ◽

Antiviral Efficacy ◽

Hsv 1

Download Full-text

Ertapenem in critically ill patients with early-onset ventilator-associated pneumonia: pharmacokinetics with special consideration of free-drug concentration

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dkl485 ◽

2006 ◽

Vol 59 (2) ◽

pp. 277-284 ◽

Cited By ~ 75

Author(s):

O. Burkhardt ◽

V. Kumar ◽

D. Katterwe ◽

J. Majcher-Peszynska ◽

B. Drewelow ◽

...

Keyword(s):

Critically Ill ◽

Drug Concentration ◽

Critically Ill Patients ◽

Early Onset ◽

Free Drug ◽

Special Consideration ◽

Ventilator Associated Pneumonia ◽

Free Drug Concentration

Download Full-text

Hummel-Dreyer method in high-performance liquid chromatography for the determination of drug-protein binding parameters

Journal of Chromatography A ◽

10.1016/0021-9673(93)80414-4 ◽

1993 ◽

Vol 648 (2) ◽

pp. 325-331 ◽

Cited By ~ 24

Author(s):

S.F. Sun ◽

C.L. Hsiao

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Protein Binding ◽

High Performance ◽

Binding Parameters ◽

Drug Protein Binding

Download Full-text

The absence of stereoselective P-glycoprotein- and multidrug resistance-associated protein-mediated transport of daunorubicin11Abbreviations: P-gp, P-glycoprotein; MRP1, multidrug resistance-associated protein; DNR, daunorubicin; WP900, daunorubicin enantiomer; Ci, intracellular free drug concentration in the cytosol; Ce: extracellular free drug concentration; Cn1, overall concentration of drug accumulated inside the cell (in the nucleus and in the acidic compartment); Cn, overall concentration of drug bound to the nucleus; Cn1 (or Cn), intracellular drug concentration; CCA, concanamycin A; and RF, resistance factor.

Biochemical Pharmacology ◽

10.1016/s0006-2952(01)00703-1 ◽

2001 ◽

Vol 62 (5) ◽

pp. 561-567 ◽

Cited By ~ 7

Author(s):

Chatchanok Loetchutinat ◽

Christine Heywang ◽

Waldemar Priebe ◽

Arlette Garnier-Suillerot

Keyword(s):

Multidrug Resistance ◽

Drug Concentration ◽

Free Drug ◽

Resistance Factor ◽

Free Drug Concentration ◽

Concanamycin A ◽

P Glycoprotein ◽

Acidic Compartment

Download Full-text

Determination of Hepatic Clearance with the Account of Drug–Protein Binding Kinetics

Journal of Pharmaceutical Sciences ◽

10.1002/jps.23235 ◽

2012 ◽

Vol 101 (10) ◽

pp. 3936-3945 ◽

Cited By ~ 7

Author(s):

Leonid M. Berezhkovskiy

Keyword(s):

Protein Binding ◽

Hepatic Clearance ◽

Binding Kinetics ◽

Protein Binding Kinetics ◽

Drug Protein Binding

Download Full-text

Monitoring Free Drug Concentration

Handbook of Drug Monitoring Methods ◽

10.1007/978-1-59745-031-7_2 ◽

2007 ◽

pp. 41-65

Author(s):

Amitava Dasgupta

Keyword(s):

Drug Concentration ◽

Free Drug ◽

Free Drug Concentration

Download Full-text

HPLC-MS/MS coupled with equilibrium dialysis method for quantification of free drug concentration of pazopanib in plasma

Heliyon ◽

10.1016/j.heliyon.2020.e03813 ◽

2020 ◽

Vol 6 (4) ◽

pp. e03813

Author(s):

Yi Long Toh ◽

Yi Yun Pang ◽

Maung Shwe ◽

Ravindran Kanesvaran ◽

Chee Keong Toh ◽

...

Keyword(s):

Drug Concentration ◽

Equilibrium Dialysis ◽

Free Drug ◽

Free Drug Concentration ◽

Dialysis Method

Download Full-text