Chemometric analysis of retention data from salting-out thin-layer chromatography in relation to structural parameters and biological activity of chosen sulphonamides

2007 ◽  
Vol 846 (1-2) ◽  
pp. 334-340 ◽  
Author(s):  
J. Flieger ◽  
R. Świeboda ◽  
M. Tatarczak
Keyword(s):  
Biological Activity ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Structural Parameters ◽  
Chemometric Analysis ◽  
Retention Data ◽  
Salting Out ◽  
Layer Chromatography

Salting-out thin-layer chromatography of transition metal complexes

1992 ◽  
Vol 626 (2) ◽  
pp. 305-309 ◽  
Author(s):  
T.J. Janjić ◽  
V. Živković ◽  
G. Vučković ◽  
M.B. Ćelap
Keyword(s):  
Transition Metal ◽  
Thin Layer ◽  
Metal Complexes ◽  
Thin Layer Chromatography ◽  
Transition Metal Complexes ◽  
Salting Out ◽  
Layer Chromatography

scholarly journals Fluorescein colchicine. Synthesis, purification, and biological activity.

1978 ◽  
Vol 76 (3) ◽  
pp. 619-627 ◽  
Author(s):  
J I Clark ◽  
D Garland
Keyword(s):  
Spectral Analysis ◽  
Biological Activity ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Fluorescein Isothiocyanate ◽  
Significant Loss ◽  
Colchicine Derivative ◽  
Layer Chromatography ◽  
Kinetics Of ◽  
Brain Tubulin

The synthesis of a fluorescent colchicine derivative permits the localization of colchicine-binding receptors in cells. Fluorescein colchicine (FC) was prepared by the addition of fluorescein isothiocyanate to deacetyl colchicine. The product, FC, was separated from the reactants by thin-layer chromatography (TLC). The purity of FC was demonstrated by TLC, UV spectral analysis, and analysis of the kinetics of photodecomposition. FC inhibited [3H] colchicine binding to purified brain tubulin. The biological activity of FC was compared to the activity of unlabeled colchicine on mitosis, motility, secretion, and myogenesis. The effects of FC were identical to those of unlabeled colchicine in all biological systems tested. The results demonstrate that FC may be substituted for colchicine in biological experiments without significant loss in specificity or effectiveness.

The study of salting-out thin-layer chromatography and their application on QSRR/QSAR of some macrolide antibiotics

2015 ◽  
Vol 147 (2) ◽  
pp. 301-310 ◽  
Author(s):  
Krzesimir Ciura ◽  
Joanna Nowakowska ◽  
Kaja Rudnicka-Litka ◽  
Piotr Kawczak ◽  
Tomasz Bączek ◽  
...  
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Macrolide Antibiotics ◽  
Salting Out ◽  
Layer Chromatography

Thin-layer chromatography and chemometric analysis in the fingerprinting of selectedScutellariaspecies

2016 ◽  
Vol 29 (4) ◽  
pp. 256-263 ◽  
Author(s):  
Mirosław A. Hawrył ◽  
Anna Hawrył ◽  
Ryszard Świeboda ◽  
Małgorzata Niemiec ◽  
Monika Waksmundzka-Hajnos
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Chemometric Analysis ◽  
Layer Chromatography
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