Adsorption properties and preparative separation of phenylethanoid glycosides from Cistanche deserticola by use of macroporous resins

2013 ◽  
Vol 937 ◽  
pp. 84-90 ◽  
Author(s):  
Boyan Liu ◽  
Jie Ouyang ◽  
Xiaofan Yuan ◽  
Liwei Wang ◽  
Bing Zhao
2009 ◽  
Vol 2009 ◽  
pp. 1-8 ◽  
Author(s):  
Zhi-feng Zhang ◽  
Yuan Liu ◽  
Pei Luo ◽  
Hao Zhang

Scutellarein-7-O-β-D-glucuronide (SG) and apigenin-7-O-β-D-glucuronide (AG) are two major bioactive constituents with known pharmacological effects inErigeron multiradiatus. In this study, a simple method for preparative separation of the two flavone glucuronides was established with macroporous resins. The performance and adsorption characteristics of eight macroporous resins including AB-8, HPD100, HPD450, HPD600, D100, D101, D141, and D160 have been evaluated. The results confirmed that D141 resin offered the best adsorption and desorption capacities and the highest desorption ratio for the two glucuronides among the tested resins. Sorption isotherms were constructed for D141 resin under optimal ethanol conditions and fitted well to the Freundlich and Langmuir models (R2>0.95). Dynamic adsorption and desorption tests was performed on column packed with D141 resin. After one-run treatment with D141 resin, the two-constituent content in the final product was increased from 2.14% and 1.34 % in the crude extract ofErigeron multiradiatusto 24.63% and 18.42% in the final products with the recoveries of 82.5% and 85.4%, respectively. The preparative separation of SG and AG can be easily and effectively achieved via adsorption and desorption on D141 resin, and the method developed can be referenced for large-scale separation and purification of flavone glucuronides from herbal raw materials.


2009 ◽  
Vol 44 (15) ◽  
pp. 3717-3734 ◽  
Author(s):  
Yan Xu ◽  
Qipeng Yuan ◽  
Xiaodan Hou ◽  
Yanping Lin

2007 ◽  
Vol 1139 (2) ◽  
pp. 206-213 ◽  
Author(s):  
Yujie Fu ◽  
Yuangang Zu ◽  
Wei Liu ◽  
Chunlian Hou ◽  
Liyan Chen ◽  
...  

2012 ◽  
Vol 40 (06) ◽  
pp. 1123-1141 ◽  
Author(s):  
Tian Wang ◽  
Xiaoying Zhang ◽  
Wenyan Xie

Cistanche deserticola Y. C. Ma (C. deserticola, "Rou Cong Rong" in Chinese) is an officinal plant that grows in arid or semi-arid areas. The dried fleshy stem of C. deserticola has been generally used as a tonic in China and Japan for many years. Modern pharmacology studies have since demonstrated that C. deserticola possesses broad medicinal functions, especially for use in hormone regulation, aperient, immunomodulatory, neuroprotective, antioxidative, anti-apoptotic, anti-nociceptive, anti-inflammatory, anti-fatigue activities and the promotion of bone formation. The phenylethanoid glycosides (PhGs) presented in C. deserticola have been identified as the major active components. This review summarizes the up-to-date and comprehensive information on C. deserticola covering the aspects of the botany, traditional uses, phytochemistry, and pharmacology.


Sign in / Sign up

Export Citation Format

Share Document