EGFR-targeted micelles containing near-infrared dye for enhanced photothermal therapy in colorectal cancer

2017 ◽  
Vol 258 ◽  
pp. 196-207 ◽  
Author(s):  
Ying-Hsia Shih ◽  
Tsai-Yueh Luo ◽  
Ping-Fang Chiang ◽  
Cheng-Jung Yao ◽  
Wuu-Jyh Lin ◽  
...  
2019 ◽  
Vol 7 (7) ◽  
pp. 2873-2888 ◽  
Author(s):  
Xu Zhang ◽  
Xiaolong Liang ◽  
Xiaotu Ma ◽  
Rui Hou ◽  
Xiaoda Li ◽  
...  

Dye-conjugated cerasome loaded with DOX exhibited high stability and controllable drug release, holding great promise in colorectal cancer photothermal chemotherapy.


2019 ◽  
Vol 8 (16) ◽  
pp. 1900409 ◽  
Author(s):  
Chunyang Zhang ◽  
Jie Liu ◽  
Huanling Guo ◽  
Wei Wang ◽  
Ming Xu ◽  
...  

2016 ◽  
Vol 8 (38) ◽  
pp. 25087-25095 ◽  
Author(s):  
Gang Chen ◽  
Kaikai Wang ◽  
Yiwen Zhou ◽  
Ling Ding ◽  
Aftab Ullah ◽  
...  

Nanomedicine ◽  
2021 ◽  
Author(s):  
Shu-Jyuan Yang ◽  
Hsiao-Ting Huang ◽  
Chung-Huan Huang ◽  
Jui-An Pai ◽  
Chung-Hao Wang ◽  
...  

Aim: 7-Ethyl-10-hydroxycamptothecin (SN-38)-loaded gold nanoshells nanoparticles (HSP@Au NPs) were developed for combined chemo-photothermal therapy to treat colorectal cancer. Materials & methods: SN-38-loaded nanoparticles (HSP NPs) were prepared by the lyophilization-hydration method, and then developed into gold nanoshells. The nanoparticles were characterized and assessed for photothermal properties, cytotoxicity and hemocompatibility in vitro. In vivo anticancer activity was tested in a tumor mouse model. Results: The HSP@Au NPs (diameter 186.9 nm, zeta potential 33.4 mV) led to significant cytotoxicity in cancer cells exposed to a near-infrared laser. Moreover, the HSP@Au NP-mediated chemo-photothermal therapy displayed significant tumor growth suppression and disappearance (25% of tumor clearance rate) without adverse side effects in vivo. Conclusion: HSP@Au NPs may be promising in the treatment of colorectal cancer in the future.


RSC Advances ◽  
2018 ◽  
Vol 8 (26) ◽  
pp. 14268-14279 ◽  
Author(s):  
Yuanyuan He ◽  
Yuanzhi Shen ◽  
Siqi Zhou ◽  
Yihui Wu ◽  
Zhenwei Yuan ◽  
...  

Development of photothermal agents for imaging-guided photothermal therapy (PTT) has been of great interest in the field of nanomedicine.


Biomaterials ◽  
2014 ◽  
Vol 35 (28) ◽  
pp. 8206-8214 ◽  
Author(s):  
Qian Chen ◽  
Chao Wang ◽  
Zhixiong Zhan ◽  
Weiwei He ◽  
Zhenping Cheng ◽  
...  

2017 ◽  
Vol 5 (9) ◽  
pp. 1803-1814 ◽  
Author(s):  
Kerong Deng ◽  
Yinyin Chen ◽  
Chunxia Li ◽  
Xiaoran Deng ◽  
Zhiyao Hou ◽  
...  

Schematic diagram of 808 nm light mediated antitumor nanotheranostic agents for synchronous magnetic targeted and MR imaging guided photothermal/photodynamic therapy.


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