Incidence of and risk factors for residual posterior capsule opacification after cataract surgery

2004 ◽  
Vol 30 (11) ◽  
pp. 2354-2358 ◽  
Author(s):  
Vinod V. Mootha ◽  
Rachel Tesser ◽  
Clifford Qualls
Keyword(s):  
Risk Factors ◽  
Cataract Surgery ◽  
Posterior Capsule Opacification ◽  
Posterior Capsule

scholarly journals Retrospective Analyses of Potential Risk Factors for Posterior Capsule Opacification after Cataract Surgery

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Shuang Wu ◽  
Nianting Tong ◽  
Lin Pan ◽  
Xiaohui Jiang ◽  
Yanan Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Cataract Surgery ◽  
Potential Risk ◽  
Posterior Capsule Opacification ◽  
Posterior Capsule ◽  
Factors Associated ◽  
Time Of Surgery ◽  
Department Of Ophthalmology ◽  
Potential Risk Factors

Purpose. To evaluate the potential risk factors of posterior capsule opacification (PCO) after cataract surgery. Methods. Data on PCO patients diagnosed from September 2015 to May 2017 were obtained from the Department of Ophthalmology at Qingdao Municipal Hospital, Qingdao, China. The factors associated with PCO were assessed using Pearson's χ2 test for univariate analyses and logistic regression for multivariate analyses. Results. Eyes (652) from 550 patients were enrolled in this study. All patients were diagnosed with PCO/non-PCO and had <3 years of follow-up after surgery. The numbers of PCO and non-PCO were 108 eyes and 544 eyes, respectively. Statistically significant associations with PCO were found for age at the time of surgery (χ2 = 78.504; p<0.001), diabetes (χ2 = 4.829; p=0.028), immune diseases (χ2 = 4.234; p=0.004), high myopia (χ2 = 5.753; p=0.016), lens nucleus hardness (χ2 = 11.046; p=0.026), surgery type (χ2 = 11.354; p=0.001), a history of vitrectomy (χ2 = 4.212; p=0.004), ocular inflammation (χ2 = 6.01; p=0.009), and the intraocular lens (IOL) type (χ2 = 8.696; p=0.003). Multivariable data analyses using logistic regression analyses of the variables showed that age at the time of surgery <60 years, diabetes, lens nucleus hardness of III–V, extracapsular cataract extraction (ECCE), postvitrectomy, and hydrophilic IOLs were significant independent risk factors associated with PCO. Conclusions. Age <60 years, diabetes, lens nucleus hardness of III–V, ECCE, postvitrectomy, and a hydrophilic IOL were significantly associated with the formation of PCO. Estimation of the incidence of and risk factors for PCO should help in patients counseling and in the design of treatment protocols to reduce or prevent its development.

scholarly journals In Vitro Growth of Lens Epithelial Cells from Cataract Patients - Association with Possible Risk Factors for Posterior Capsule Opacification

2014 ◽  
Vol 8 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Karin Sundelin ◽  
Anne Petersen ◽  
Yalda Soltanpour ◽  
Madeleine Zetterberg
Keyword(s):  
Risk Factors ◽  
Epithelial Cells ◽  
Cataract Surgery ◽  
Calf Serum ◽  
Posterior Capsule Opacification ◽  
Posterior Capsule ◽  
Human Lens ◽  
Lens Epithelial Cells ◽  
Proliferative Capacity

Aim : Inter-individual differences in intrinsic proliferative capacity of lens epithelial cells may have importance for the risk of developing posterior capsule opacification (PCO) after cataract surgery. The purpose of the present study was to determine growth of human lens epithelial cells (HLEC) in culture and investigate possible associations with clinical characteristics of the donors, such as age, sex, pseudoexfoliation, uveitis and diabetes. Methods : Pieces of lens capsule and adhering lens epithelial cells were obtained through capsulorhexis at cataract surgery. Specimens were cultured in a humidified CO2-incubator using standard culture medium and 5% fetal calf serum for two weeks after which cultured cells were stained with carboxy-fluorescein diacetate succinimidyl ester. Image processing software was used to determine the area of the confluent epithelial cell layer in relation to the size of the original capsule specimen. Results : The increase in area of confluent HLEC showed a negative correlation with diabetes at the first week after surgery. Lower age and female sex showed border-line significant associations with a higher rate of cell proliferation. The presence of pseudoexfoliation in vivo did not significantly affect cell growth in culture postoperatively. Nor did installation of xylocain in the anterior chamber during surgery. Conclusion : Diabetes is associated with lower rate of proliferation of lens epithelial cells in culture. The lack of strong correlations between in vitro growth and known risk factors for PCO in the donors suggest that other factors than the proliferative capacity of the cells per se are important for PCO formation.

scholarly journals Frequency of Complications Following Cataract Surgery in Diabetic Patients at Tertiary Care Hospital

2022 ◽  
Vol 9 (1) ◽  
pp. 75-81
Author(s):  
Muhammad Bilal ◽  
Shafqat Ali Shah ◽  
Marina Murad ◽  
Saad Ali ◽  
Ammad Ali ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Tertiary Care ◽  
Case Series ◽  
Female Gender ◽  
Posterior Capsule Opacification ◽  
Posterior Capsule ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Case Series Study

OBJECTIVES: To determine the frequency of complications following cataract surgery in diabetic patients admitted in the ophthalmology unit. METHODOLOGY: A prospective descriptive interventional case series study was conducted after approval of the ethical committee, from June 2017-June 2020 at the Ophthalmology department MTI-MMC. A total of 129 patients from either gender were enrolled in study. All the study patients went through detailed history and complete ocular examination. After necessary investigations, surgical procedure was carried out. Results were analyzed through the SPSS-24 version. RESULTS: Out of the total 129 eyes of the diabetic patients, fifty-nine (45.7%) were males and seventy (54.3%) were females with a ratio of 1:1.2. Uveitis leads the chart in complications found in twenty (15.50%) eyes while PODR being the least common found in only ten (7.75%) eyes. Worse visual acuity was observed in fourteen (10.85%) eyes. Striate keratopathy and posterior capsule opacification were found in sixteen (12.40%) and fifteen (11.62%) eyes respectively. Among the patients, 15.7% were having more than one complication during follow-up visits and eighty-eight (68.2%) eyes were found to have none complication. The age group 51-60 years observed frequent complications as compared to other groups. Similarly female gender (38.57%) has frequent complications as compared to males (2.7%). CONCLUSION: The study concludes Uveitis as the most common complication observed in 15.50% 0f the eyes while worse visual acuity (10.85%) and progression of diabetic retinopathy (7.75%) being the least common. Striate keratopathy was found in 12.40% while posterior capsule opacification in 11.62% of the eyes.

Evaluation of posterior capsule opacification after cataract surgery using Liquifaction Method

2011 ◽  
Vol 89 (s248) ◽  
pp. 0-0
Author(s):  
M KALFERTOVA ◽  
M BUROVA ◽  
J NEKOLOVA ◽  
N JIRASKOVA ◽  
P ROZSIVAL
Keyword(s):  
Cataract Surgery ◽  
Posterior Capsule Opacification ◽  
Posterior Capsule

scholarly journals Nd:YAG Capsulotomy after Phacoemulsification in Vitrectomized Eyes: Effects of Pars Plana Vitrectomy on Posterior Capsule Opacification

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Jong Hwa Jun ◽  
Kwang Soo Kim ◽  
Sung Dong Chang
Keyword(s):  
Cataract Surgery ◽  
Medical Records ◽  
Pars Plana Vitrectomy ◽  
Posterior Capsule Opacification ◽  
Posterior Capsule ◽  
Time Interval ◽  
Time Intervals ◽  
Nd:Yag Laser Capsulotomy ◽  
Pars Plana ◽  
Hydrophobic Acrylic

To compare the progression of posterior capsule opacification (PCO) in patients who required Nd:YAG laser capsulotomy following either combined cataract surgery with pars plana vitrectomy (PPV; C-CV), sequential cataract surgery after PPV (S-CV), or cataract surgery alone (CA). The medical records of 321 patients (408 eyes) who underwent Nd:YAG capsulotomy were retrospectively evaluated. The CA group had a significantly longer time interval from cataract surgery to capsulotomy than that of both the CV group(P=0.006)and the S-CV(P=0.013)and C-CV(P=0.042)subgroups when age-matched comparisons were used. CV patients who implanted a hydrophobic acrylic IOL had shorter time intervals than those of CA patients(P=0.028). CV patients had larger hazard of earlier capsulotomy than CA patients (hazard ratio (HR) = 1.337; 95% confidence interval (CI) 1.100–1.625;P=0.004). C-CV and S-CV patients both had larger hazard than CA patients in earlier capsulotomy (HR=1.304; 95%CI=1.007–1.688;P=0.044,HR=1.361; 95%  CI=1.084–1.709;P=0.008, resp.). PCO progresses more rapidly in patients undergoing combined or sequential cataract surgery and PPV than in patients undergoing CA.

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