scholarly journals Safety and acceptability of human papillomavirus testing of self-collected specimens: A methodologic study of the impact of collection devices and HPV assays on sensitivity for cervical cancer and high-grade lesions

2018 ◽  
Vol 99-100 ◽  
pp. 22-30 ◽  
Author(s):  
Maarit K. Leinonen ◽  
Kristina Schee ◽  
Christine M. Jonassen ◽  
A. Kathrine Lie ◽  
Camilla F. Nystrand ◽  
...  
Author(s):  
Mee-seon Kim ◽  
Eun Hee Lee ◽  
Moon-il Park ◽  
Jae Seok Lee ◽  
Kisu Kim ◽  
...  

(1) Background: Cervical cancer is one of the most common cancers in Korean women. This study was performed to discover the utility of HPV (Human Papillomavirus) testing in screening of cervical lesions and to provide the prevalence of HPV and the genotype distribution in a single center of Korea. (2) Methods: A total of 15,141 women who underwent both HPV testing and cervical cytology were enrolled in this retrospective medical record review study. (3) Results: HPV testing showed higher sensitivity than cytology for the detection of histological high-grade squamous lesions. Furthermore, the sensitivity and specificity of HPV testing varied depending on the method used. The BD Onclarity™ HPV assay had higher sensitivity (90%) than the MyHPV CHIP™ kit (all types of HPV: 82%; high-risk HPV: 76%) for high-grade squamous lesions. A combination of MyHPV CHIP™ and cytology detected 90.9% (30/33) of histological high-grade squamous lesions. A combination of BD Onclarity™ HPV assay and cytology detected 96.55% (84/87) of histological high-grade squamous lesions. In addition, HPV prevalence and genotype distribution were different depending on the HPV testing method used. (4) Conclusion: HPV testing showed higher sensitivity than cytology, but the sensitivity and specificity of HPV testing had variation depending on the method used.


2010 ◽  
Vol 118 (3) ◽  
pp. 146-156 ◽  
Author(s):  
Panduka Samarawardana ◽  
Donna L. Dehn ◽  
Meenakshi Singh ◽  
Douglas Franquemont ◽  
Chesney Thompson ◽  
...  

2014 ◽  
Vol 134 (3) ◽  
pp. 534-539 ◽  
Author(s):  
Adela Carrillo-García ◽  
Sergio Ponce-de-León-Rosales ◽  
David Cantú-de-León ◽  
Verónica Fragoso-Ontiveros ◽  
Imelda Martínez-Ramírez ◽  
...  

2003 ◽  
Vol 127 (8) ◽  
pp. 984-990
Author(s):  
David R. Bolick

Abstract Human papillomavirus testing is becoming an integral component of cervical cancer screening. Market forces will require most laboratories that perform Papanicolaou tests to develop a system for handling human papillomavirus testing also. Data and information are presented that may facilitate laboratories when addressing the following issues in the process of developing a human papillomavirus testing service: Which methodology is the best fit for the laboratory? Is it better to develop an in-house testing service or to send it out? How do I get started? What are the financial and economic issues, and how should they be managed?


2017 ◽  
Vol 26 (6) ◽  
pp. 609-615 ◽  
Author(s):  
Constance Mao ◽  
Shalini L. Kulasingam ◽  
Hilary K. Whitham ◽  
Stephen E. Hawes ◽  
John Lin ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document