Evaluation of a rapid point-of-care HIV screening program in an emergency department setting in Detroit, Michigan

2018 ◽  
Vol 106 ◽  
pp. 11-12 ◽  
Author(s):  
Weiming Zhu ◽  
Kimberly Mumby ◽  
Doreen Dankerlui ◽  
Jake Manteuffel ◽  
Cal Ham ◽  
...  
2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S513-S513
Author(s):  
Elizabeth A Aguilera ◽  
Gilhen Rodriguez ◽  
Gabriela P Del Bianco ◽  
Gloria Heresi ◽  
James Murphy ◽  
...  

Abstract Background The Emergency Department (ED) at Memorial Hermann Hospital (MHH) - Texas Medical Center (TMC), Houston, Texas has a long established screening program targeted at detection of HIV infections. The impact of the COVID-19 pandemic on this screening program is unknown. Methods The Routine HIV screening program includes opt-out testing of all adults 18 years and older with Glasgow score > 9. HIV 4th generation Ag/Ab screening, with reflex to Gennius confirmatory tests are used. Pre-pandemic (March 2019 to February 2020) to Pandemic period (March 2020 to February 2021) intervals were compared. Results 72,929 patients visited MHH_ED during the pre-pandemic period and 57,128 in the pandemic period, a 22% decline. The number of patients tested for HIV pre-pandemic was 9433 and 6718 pandemic, a 29% decline. When the pandemic year was parsed into first and last 6 months interval and compared to similar intervals in the year pre pandemic, 39% followed by 16% declines in HIV testing were found. In total, 354 patients were HIV positives, 209, (59%) in the pre-pandemic and 145 (41%) in the pandemic period.The reduction in new HIV infections found was directly proportional to the decline in patients visiting the MHH-ED where the percent of patients HIV positive was constant across intervals (2.21% vs 2.26%). Demographic and outcome characteristics were constant across the compared intervals. Conclusion The COVID -19 pandemic reduced detection of new HIV infections by screening in direct proportion to the reduction in MHH-ED patient visits. The impact of COVID-19 pandemic decreased with duration of the pandemic. Disclosures All Authors: No reported disclosures


2011 ◽  
Vol 58 (1) ◽  
pp. S71-S73.e1 ◽  
Author(s):  
Lee Wilbur ◽  
Gretchen Huffman ◽  
Stephanie Lofton ◽  
John T. Finnell

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250195
Author(s):  
Robert Deiss ◽  
Carolina V. Loreti ◽  
Ana G. Gutierrez ◽  
Eudoxia Filipe ◽  
Milton Tatia ◽  
...  

Background Cryptococcal meningitis is a leading cause of HIV-related mortality in sub-Saharan Africa, however, screening for cryptococcal antigenemia has not been universally implemented. As a result, data concerning cryptococcal meningitis and antigenemia are sparse, and in Mozambique, the prevalence of both are unknown. Methods We performed a retrospective analysis of routinely collected data from a point-of-care cryptococcal antigen screening program at a public hospital in Maputo, Mozambique. HIV-positive patients admitted to the emergency department underwent CD4 count testing; those with pre-defined abnormal vital signs or CD4 count ≤ 200 cells/μL received cryptococcal antigen testing and lumbar punctures if indicated. Patients with CM were admitted to the hospital and treated with liposomal amphotericin B and flucytosine; their 12-week outcomes were ascertained through review of medical records or telephone contact by program staff made in the routine course of service delivery. Results Among 1,795 patients screened for cryptococcal antigenemia between March 2018—March 2019, 134 (7.5%) were positive. Of patients with cryptococcal antigenemia, 96 (71.6%) were diagnosed with CM, representing 5.4% of all screened patients. Treatment outcomes were available for 87 CM patients: 24 patients (27.6%) died during induction treatment and 63 (72.4%) survived until discharge; of these, 38 (60.3%) remained in care, 9 (14.3%) died, and 16 (25.3%) were lost-to follow-up at 12 weeks. Conclusions We found a high prevalence of cryptococcal antigenemia and meningitis among patients screened at an emergency department in Maputo, Mozambique. High mortality during and after induction therapy demonstrate missed opportunities for earlier detection of cryptococcal antigenemia, even as point-of-care screening and rapid assessment in an emergency room offer potential to improve outcomes.


2009 ◽  
Vol 23 (4) ◽  
pp. 245-250 ◽  
Author(s):  
Douglas A.E. White ◽  
Otis U. Warren ◽  
Alicia N. Scribner ◽  
Bradley W. Frazee

PLoS ONE ◽  
2011 ◽  
Vol 6 (10) ◽  
pp. e25575 ◽  
Author(s):  
Rochelle P. Walensky ◽  
Bethany L. Morris ◽  
William M. Reichmann ◽  
A. David Paltiel ◽  
Christian Arbelaez ◽  
...  

2018 ◽  
Vol 5 ◽  
pp. 12-17 ◽  
Author(s):  
P.S. Lager ◽  
M.E. Attema-de Jonge ◽  
M.P. Gorzeman ◽  
L.E. Kerkvliet ◽  
E.J.F. Franssen

2021 ◽  
Vol 61 (5) ◽  
pp. S32-S38
Author(s):  
Angela B. Hutchinson ◽  
Robin J. MacGowan ◽  
Andrew D. Margolis ◽  
Madeline G. Adee ◽  
Wendy Wen ◽  
...  

2017 ◽  
Vol 28 (11) ◽  
pp. 1124-1129 ◽  
Author(s):  
Yu-Hsiang Hsieh ◽  
Kaylin J Beck ◽  
Richard E Rothman ◽  
Megan Gauvey-Kern ◽  
Alonzo Woodfield ◽  
...  

Kiosk-facilitated HIV self-testing has been shown to be accurate and well accepted by emergency department (ED) patients. We investigated factors associated with patients who preferred self-testing over testing performed by health professionals in an ED-based HIV screening program. This opt-in program evaluation studied 332 patients in an inner-city academic ED from February 2012 to April 2012, when a kiosk-based HIV self-testing program was standard of care. The first kiosk in the 2-stage system registered patients and assessed their interest in screening, while the second kiosk gathered demographic and risk factor information and also provided self-testing instructions. Patients who declined to self-test were offered testing by staff. Broad eligibility included patients aged 18–64 years who were not critically ill, English-speaking, able to provide informed consent, and registered during HIV program operational hours. Data were analyzed using descriptive statistical analysis and Chi squared tests; 160 (48.2%) of 332 patients consenting to testing chose to use a kiosk to guide them performing self-testing. Patients aged 25–29 years and those whose primary ED diagnosis was not infectious disease-related were more likely to prefer HIV self-testing (OR = 2.19, 95% CI: 1.17–4.10; OR = 1.79, 95% CI: 1.03–3.12). HIV self-testing in the ED could serve as a complementary testing approach to the conventional modality.


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