Anti-biofilm activity of zinc oxide and hydroxyapatite nanoparticles as dental implant coating materials

Implant infection is one the current complications of implant restoration. Incorporation of a material that possesses antibacterial property is crucial in combating implant infection. In this study, polyaniline (PANI) is incorporated in ginseng encapsulated poly (lactic-co-glycolic acid) (PLGA) microcapsules to equip the microcapsules with an antibacterial effect. The microcapsules are intended for drug delivery purpose as the ginseng is comprised of abundant therapeutic values and the PLGA is known for its degradation property. The microcapsules were coated on stainless steel 316L using an electro-deposition technique. The chemical composition, morphology and antibacterial activity of the samples were analyzed through ATR-FTIR, SEM and bacterial count test. A greater volume of microcapsules was coated on the stainless steel 316L with the addition of PANI through the appearance of intense ginseng (O–H and C=C bands) and PLGA (C=O) peaks on the ATR-FTIR spectra and through the visualization of spherical morphology of microcapsules on the pre-treated metal. The incorporation of PANI also has induced the antibacterial efficacy of the microcapsules to 87.64%. Therefore, PANI has served as an antibacterial agent that could be useful in the development of implant coating materials while driving the formation of ginseng encapsulated PLGA microcapsules.

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Hydrothermal treatment for TiN as abrasion resistant dental implant coating and its fibroblast response

Materials Science and Engineering C ◽

10.1016/j.msec.2014.12.059 ◽

2015 ◽

Vol 49 ◽

pp. 1-6 ◽

Cited By ~ 24

Author(s):

Xingling Shi ◽

Lingli Xu ◽

Melvin L. Munar ◽

Kunio Ishikawa

Keyword(s):

Hydrothermal Treatment ◽

Dental Implant ◽

Implant Coating

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Co-sputtered Antibacterial and Biocompatible Nanocomposite Titania-Zinc Oxide thin films on Si substrates for Dental Implant applications

Materials Technology ◽

10.1080/10667857.2018.1488924 ◽

2018 ◽

Vol 34 (1) ◽

pp. 32-42 ◽

Cited By ~ 2

Author(s):

Shreya Goel ◽

Paritosh Dubey ◽

Supriyo Ray ◽

Rengaswamy Jayaganthan ◽

Aditya Bhusan Pant ◽

...

Keyword(s):

Thin Films ◽

Zinc Oxide ◽

Dental Implant ◽

Oxide Thin Films ◽

Si Substrates

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Titanium Nitride Modified by Hydrothermal Treatment in Calcium Acetate Solution

Materials Science Forum ◽

10.4028/www.scientific.net/msf.815.446 ◽

2015 ◽

Vol 815 ◽

pp. 446-450

Author(s):

Xing Ling Shi ◽

Ling Li Xu ◽

Guang Hong Zhou ◽

Le Te Bang

Keyword(s):

Surface Modification ◽

Titanium Nitride ◽

Hydrothermal Treatment ◽

Dental Implant ◽

Pure Titanium ◽

Surface Hardness ◽

Treatment Temperature ◽

Acetate Solution ◽

Tin Coating ◽

Implant Coating

Dental implant made of pure titanium (Ti) has become one important option to restore the function of lost tooth. However, because of insufficient hardness, it is always scratched during oral hygieneprocedures. To improve its surface hardness,titanium nitride (TiN) coating was prepared. Soft tissue - implant interface is important for blocking bacteria invasion, therefore surface modification is necessary to improve biocompatibility of TiN for fibroblasts.In the present study, TiN coating was modified by hydrothermal treatment incalcium acetate (CaAc) solution and effect of hydrothermal treatment temperature was studied. After treatment,calcium (Ca) wassuccessfully combined into TiN surface and the surface morphology, roughness and hardness were not changed below 140 °C. It is expected that, surface modification with Ca by hydrothermal treatment could made TiN a promising dental implant coating.

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Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review

Coatings ◽

10.3390/coatings11111401 ◽

2021 ◽

Vol 11 (11) ◽

pp. 1401

Author(s):

Gang Tan ◽

Jing Xu ◽

Walter Munesu Chirume ◽

Jieyu Zhang ◽

Hui Zhang ◽

...

Keyword(s):

Hot Spot ◽

Orthopedic Implants ◽

Implant Failure ◽

Social Benefits ◽

Orthopedic Implant ◽

Common Complication ◽

Coating Materials ◽

Implant Infection ◽

Implant Coating ◽

Anti Inflammatory

Orthopedic implant failure is the most common complication of orthopedic surgery, causing serious trauma and resulting in a tremendous economic burden for patients. There are many reasons for implant failure, among which peri-implant infection (or implant-related infection) and aseptic loosening are the most important. At present, orthopedic doctors have many methods to treat these complications, such as revision surgery, which have shown good results. However, if peri-implant infection can be prevented, this will bring about significant social benefits. Many studies have focused on adding antibacterial substances to the implant coating, and with a deeper understanding of the mechanism of implant failure, adding such substances by different modification methods has become a research hot spot. This review aims to summarize the antibacterial and anti-inflammatory substances that can be used as coating materials in orthopedic implants and to provide a reference for the prevention and treatment of implant failure caused by implant-related infection and excessive inflammation.

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Development of dental implant coating with minocycline-loaded niosome for antibacterial application

Journal of Drug Delivery Science and Technology ◽

10.1016/j.jddst.2020.101555 ◽

2020 ◽

Vol 56 ◽

pp. 101555 ◽

Cited By ~ 2

Author(s):

Nattarat Wongsuwan ◽

Anupma Dwivedi ◽

Salunya Tancharoen ◽

Norased Nasongkla

Keyword(s):

Dental Implant ◽

Implant Coating

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