scholarly journals Antibacterial Effect of Ginseng/polyaniline Encapsulated in Poly(Lactic-co-glycolic Acid) Microcapsules Coating on Stainless Steel 316L

2019 ◽  
Vol 253 ◽  
pp. 03001
Author(s):  
Siti Khadijah Lukman ◽  
Syafiqah Saidin

Implant infection is one the current complications of implant restoration. Incorporation of a material that possesses antibacterial property is crucial in combating implant infection. In this study, polyaniline (PANI) is incorporated in ginseng encapsulated poly (lactic-co-glycolic acid) (PLGA) microcapsules to equip the microcapsules with an antibacterial effect. The microcapsules are intended for drug delivery purpose as the ginseng is comprised of abundant therapeutic values and the PLGA is known for its degradation property. The microcapsules were coated on stainless steel 316L using an electro-deposition technique. The chemical composition, morphology and antibacterial activity of the samples were analyzed through ATR-FTIR, SEM and bacterial count test. A greater volume of microcapsules was coated on the stainless steel 316L with the addition of PANI through the appearance of intense ginseng (O–H and C=C bands) and PLGA (C=O) peaks on the ATR-FTIR spectra and through the visualization of spherical morphology of microcapsules on the pre-treated metal. The incorporation of PANI also has induced the antibacterial efficacy of the microcapsules to 87.64%. Therefore, PANI has served as an antibacterial agent that could be useful in the development of implant coating materials while driving the formation of ginseng encapsulated PLGA microcapsules.

Coatings ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1401
Author(s):  
Gang Tan ◽  
Jing Xu ◽  
Walter Munesu Chirume ◽  
Jieyu Zhang ◽  
Hui Zhang ◽  
...  

Orthopedic implant failure is the most common complication of orthopedic surgery, causing serious trauma and resulting in a tremendous economic burden for patients. There are many reasons for implant failure, among which peri-implant infection (or implant-related infection) and aseptic loosening are the most important. At present, orthopedic doctors have many methods to treat these complications, such as revision surgery, which have shown good results. However, if peri-implant infection can be prevented, this will bring about significant social benefits. Many studies have focused on adding antibacterial substances to the implant coating, and with a deeper understanding of the mechanism of implant failure, adding such substances by different modification methods has become a research hot spot. This review aims to summarize the antibacterial and anti-inflammatory substances that can be used as coating materials in orthopedic implants and to provide a reference for the prevention and treatment of implant failure caused by implant-related infection and excessive inflammation.


2016 ◽  
Vol 515 (1-2) ◽  
pp. 460-466 ◽  
Author(s):  
Zulaika Miswan ◽  
Siti Khadijah Lukman ◽  
Fadzilah Adibah Abd Majid ◽  
Mun Fai Loke ◽  
Syafiqah Saidin ◽  
...  

2012 ◽  
Vol 15 (3) ◽  
pp. 112-122
Author(s):  
Ali H. Ataiwi ◽  
◽  
Abdul Khaliq F. Hamood ◽  
Rana A. Majed ◽  
◽  
...  

Author(s):  
M. Carraturo ◽  
G. Alaimo ◽  
S. Marconi ◽  
E. Negrello ◽  
E. Sgambitterra ◽  
...  

AbstractAdditive manufacturing (AM), and in particular selective laser melting (SLM) technology, allows to produce structural components made of lattice structures. These kinds of structures have received a lot of research attention over recent years due to their capacity to generate easy-to-manufacture and lightweight components with enhanced mechanical properties. Despite a large amount of work available in the literature, the prediction of the mechanical behavior of lattice structures is still an open issue for researchers. Numerical simulations can help to better understand the mechanical behavior of such a kind of structure without undergoing long and expensive experimental campaigns. In this work, we compare numerical and experimental results of a uniaxial tensile test for stainless steel 316L octet-truss lattice specimen. Numerical simulations are based on both the nominal as-designed geometry and the as-build geometry obtained through the analysis of µ-CT images. We find that the use of the as-build geometry is fundamental for an accurate prediction of the mechanical behavior of lattice structures.


2021 ◽  
pp. 102104
Author(s):  
Xianglong Wang ◽  
Oscar Sanchez-Mata ◽  
Sıla Ece Atabay ◽  
Jose Alberto Muñiz-Lerma ◽  
Mohammad Attarian Shandiz ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document