Sensitivity and specificity of a new indicator test (Neuropad) for the diagnosis of peripheral neuropathy in type 2 diabetes patients: a comparison with clinical examination and nerve conduction study

2007 ◽  
Vol 21 (6) ◽  
pp. 353-358 ◽  
Author(s):  
Nikolaos Papanas ◽  
Georgios Giassakis ◽  
Konstantinos Papatheodorou ◽  
Dimitrios Papazoglou ◽  
Christodoulos Monastiriotis ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Peripheral Neuropathy ◽  
Sensitivity And Specificity ◽  
Clinical Examination ◽  
Nerve Conduction Study ◽  
Nerve Conduction ◽  
Diabetes Patients

scholarly journals Comparative study of detection of diabetic neuropathy by clinical and nerve conduction study in type 2 diabetes mellitus patients

2018 ◽  
Vol 5 (2) ◽  
pp. 380 ◽  
Author(s):  
Gurinder Mohan ◽  
Manish Chandey ◽  
Anusha Monga ◽  
Parik Dev
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Diabetic Neuropathy ◽  
Clinical Features ◽  
Clinical Examination ◽  
Nerve Conduction Study ◽  
Nerve Conduction

Background: Diabetes mellitus is known for its complications such as retinopathy, neuropathy and nephropathy. Diabetic neuropathy is one of the devastating complication associated with diabetes mellitus. The objective of this study was to detect sensory motor neuropathy in type 2 Diabetes mellitus by clinical examination and nerve conduction study and to correlate clinical features of peripheral neuropathy with nerve conduction study in Type 2 Diabetes mellitus.Methods: This study was undertaken to study types of neuropathy in type 2 diabetes and to correlate clinical features of peripheral neuropathy with nerve conduction study in type 2 diabetes mellitus.100 patients with diabetes whose onset of diabetes mellitus after age of 30 years and duration of diabetes 5 years or more visiting SGRDIMSR, Vallah, Amritsar were subjected to nerve conduction study to find out peripheral neuropathy.Results: Eight four percentage patients were found to have neuropathy on NCS whereas only 61% of patients were found to have neuropathy on clinical examination and detection rate with NCS was statistically significant (p <0.001) as compared to clinical examination.Conclusions: NCS helps in early detection of neuropathy and most common form of diabetic neuropathy is distal symmetrical polyneuropathy.

scholarly journals Evaluation of sural nerve automated nerve conduction study in the diagnosis of peripheral neuropathy in patients with type 2 diabetes mellitus

2016 ◽  
Vol 2 ◽  
pp. 390-393 ◽  
Author(s):  
Georgia Chatzikosma ◽  
Kalliopi Pafili ◽  
Maria Demetriou ◽  
Dimitrios Papazoglou ◽  
Konstantinos Vadikolias ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Nerve Conduction Study ◽  
Nerve Conduction ◽  
Sural Nerve

scholarly journals Assessment of Nerve Conduction Study and Electroencephalogram Abnormalities in Type 2 Diabetes Mellitus

2016 ◽  
Vol 23 (2) ◽  
pp. 159-168 ◽  
Author(s):  
Farah N. Abass ◽  
Moshtak Abdul-Atheem ◽  
Hanan F. Aswad
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Nerve Conduction Study ◽  
Nerve Conduction ◽  
Diabetic Patients ◽  
Control Subjects ◽  
And Control

AbstractBackground and aims: This study aims to evaluate the electroencephalographic and nerve conduction changes in type 2 diabetes mellitus (T2DM) patients with and without peripheral neuropathy (DPN) and to investigate the relationship with other variables such as age, gender, duration of the diabetes and the degree of metabolic control.Materials and methods: This was a cross-sectional study, including 100 patients with T2DM and 100 control subjects, aged 34 to 77 years. All patients enrolled in the study were subjected to full assessment, including: history, biochemical and electrophysiological tests.Results: The study found that patients with diabetic peripheral neuropathy (DPN) in comparison to patients without DPN and control subjects were older, had longer duration of diabetes and poorer glycemic control reflected by fasting blood glucose and glycated hemoglobin. The electrophysiological findings showed that patients with DPN have significant differences in nerve conduction study (NCS) parameters when compared to patients without DPN and control subjects in the form of axonal degeneration and demyelination. They also had abnormalities of the electroencephalogram (EEG) which are correlated with nerve conduction study severity.Conclusion: Routine NCS is an important method for evaluating DPN. Investigating sensory nerves of lower limbs is helpful in discovering the early stages of DPN when other tested nerves are normal. The F-wave can be used as a sensitive indicator for the early diagnosis of DPN and it can help to detect the subclinical lesions. EEG examination in diabetic patients with severe DPN is important in showing the defect in the central nervous system.

scholarly journals The Effects of Combined Exercise Training (Resistance-Aerobic) on Serum Kinesin and Physical Function in Type 2 Diabetes Patients with Diabetic Peripheral Neuropathy (Randomized Controlled Trials)

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Seyedeh Hoda Seyedizadeh ◽  
Sadegh Cheragh-Birjandi ◽  
Mohammad Reza Hamedi Nia
Keyword(s):  
Type 2 Diabetes ◽  
Peripheral Neuropathy ◽  
Exercise Training ◽  
Physical Function ◽  
Diabetic Peripheral Neuropathy ◽  
Diabetic Patients ◽  
Combined Exercise ◽  
Combined Exercise Training ◽  
Diabetes Patients

Diabetic peripheral neuropathy is one of the most common chronic complications of diabetics which causes nerve damage and muscle strength decrease in patients. This in turn results in imbalance leading to the diabetic patients’ daily activity disparity. The present investigation was conducted to specifically study the effects of combined training (resistance-aerobic) on serum kinesin-1 and physical function in type 2 diabetes patients with diabetic peripheral neuropathy. 24 diabetic neuropathic females were randomly to be selected out and divided into two experimental and control groups. The experimental group received resistance-aerobic training for 3 sessions during eight weeks. The exercise training included resistance exercises with 2-3 sets, 6-7 exercise stations, 8-12 repetitions (reps), and 3-5 minutes of rest in between the exercises, and the aerobic exercises contained 50-65% of heart rate reserve (HRR) for 3 minutes with 30 seconds of rest interval between sets and 5-10 repetitions. Results show that the serum kinesin-1 level and aerobic endurance declined after eight weeks of combined (resistance-aerobic) exercise training, but this decrease was not significant. The upper body strength increased but it was not significant, while the lower body showed a significant strength increase. With regard to the progressive nature of diabetic peripheral neuropathy, it seems that even the little changes resulting from the combined exercise training can be useful. Nevertheless, more research is required in this area.

scholarly journals The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Azusa Ito ◽  
Hiroshi Kunikata ◽  
Masayuki Yasuda ◽  
Shojiro Sawada ◽  
Keiichi Kondo ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Conduction Velocity ◽  
Nerve Conduction ◽  
Nerve Conduction Velocity ◽  
Neuronal Damage ◽  
Intima Media Thickness ◽  
Clinical Findings ◽  
Diabetes Patients

Purpose. Nerve conduction velocity (NCV) is an indicator of neuronal damage in the distal segment of the peripheral nerves. Here, we determined the association between NCV and other systemic and ocular clinical findings, in type 2 diabetes patients with early diabetic retinopathy (DR). Methods. This study included 42 eyes of 42 type 2 diabetes patients (median age: 54 years) with no DR or with mild nonproliferative DR. Standard statistical techniques were used to determine associations between clinical findings. Results. Sural sensory conduction velocity (SCV) and tibial motor conduction velocity (MCV) were significantly lower in mild nonproliferative DR patients than patients with no DR (P=0.008 and P=0.01, resp.). Furthermore, logistic regression analyses revealed that sural SCV and tibial MCV were independent factors contributing to the presence of mild nonproliferative DR (OR 0.83, P=0.012 and OR 0.69 P=0.02, resp.). Tibial MCV was correlated with choroidal thickness (CT) (P=0.01), and a multiple regression analysis revealed that age, tibial MCV, and carotid intima-media thickness were independent associating factors with CT (P=0.035, P=0.015, and P=0.008, resp.). Conclusions. Our findings suggest that reduced NCV may be closely associated with early DR in type 2 diabetes patients. Thus, reduced nerve conduction is a potential early biomarker of DR.

Interleukin-4 Gene Intron 3 VNTR Polymorphism in Type 2 Diabetes Patients with Peripheral Neuropathy

2017 ◽  
Vol 47 (2) ◽  
pp. 146-153 ◽  
Author(s):  
Monika Buraczynska ◽  
Kinga Buraczynska ◽  
Pawel Zukowski ◽  
Andrzej Ksiazek
Keyword(s):  
Type 2 Diabetes ◽  
Peripheral Neuropathy ◽  
Interleukin 4 ◽  
Vntr Polymorphism ◽  
Diabetes Patients
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