Anti-inflammatory activity of Trichodesma indicum root extract in experimental animals

2006 ◽  
Vol 104 (3) ◽  
pp. 410-414 ◽  
Author(s):  
James B. Perianayagam ◽  
S.K. Sharma ◽  
K.K. Pillai
Keyword(s):  
Inflammatory Activity ◽  
Root Extract ◽  
Experimental Animals ◽  
Anti Inflammatory

scholarly journals Ethanol Extract of Brassica Rapa Attenuate the Complete Freund’s Adjuvant-Induced Inflammation in Rats

2021 ◽  
Vol 14 (4) ◽  
pp. 2337-2345
Author(s):  
Bhupesh Chandra Semwal ◽  
Neha Singh and Shilpi Pathak
Keyword(s):  
Brassica Rapa ◽  
Ethanol Extract ◽  
Inflammatory Activity ◽  
Hematological Parameter ◽  
Phytochemical Analysis ◽  
Root Extract ◽  
Current Investigation ◽  
Edible Plant ◽  
Experimental Animals ◽  
Anti Inflammatory

Turnip is an ancient edible plant belongs to family Braaicacaceae. Traditionally it is used for the treatment of various disorders such as diabetes, hepatotoxicity, ulcer, and anti-inflammatory activity. Therefore the current investigation was attempted to investigate the anti-inflammatory activity of Brassica rapa root extract against complete fluids adjuvant induced inflammation in experimental animals. The Ethanol extract of Brassica rapa was prepared by a hot extraction procedure and phytochemical analysis of different extract was done by different chemical tests. Daily oral treatment of indomethacin, and extract for twenty-one days after three days of CFA administration significantly decrease the paw volume, hepatic biomarkers as well as ameliorated the level of a hematological parameter such as hemoglobin, RBC, WBC, ESR and bodyweight of experimental animals. From the result of the current investigation, it can be concluded that the Brassica rapa extract possesses anti-inflammatory activity. Further study is required to explore the mechanism responsible for its anti-inflammatory activity.

Analgesic and anti-inflammatory activity of a crude root extract of Pfaffia glomerata (Spreng) Pedersen

2005 ◽  
Vol 96 (1-2) ◽  
pp. 87-91 ◽  
Author(s):  
A.G. Neto ◽  
J.M.L.C. Costa ◽  
C.C. Belati ◽  
A.H.C. Vinhólis ◽  
L.S. Possebom ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Root Extract ◽  
Pfaffia Glomerata ◽  
Anti Inflammatory

scholarly journals Experimental clinical substantiation of application of immobilized forms of sodium hypochlorite in treatment of infected pancreatonecrosis

2017 ◽  
Vol 176 (6) ◽  
pp. 32-37
Author(s):  
B. S. Sukovatykh ◽  
V. A. Zhukovskiy ◽  
Yu. Yu. Blinkov ◽  
A. I. Itinson ◽  
E. A. Elenskaya ◽  
...  
Keyword(s):  
Experimental Study ◽  
Postoperative Complications ◽  
Clinical Research ◽  
Microbial Activity ◽  
Sodium Hypochlorite ◽  
Inflammatory Activity ◽  
Experimental Animals ◽  
Lesser Sac ◽  
Anti Inflammatory

OBJECTIVE. The study substantiated the possibility of application of sodium hypochlorite for treatment of infected pancreatonecrosis. MATERIAL AND METHODS. The experimental study was conducted on 288 rats. Clinical research was carried out on 94 patients who were divided into two statistically homogenous groups. «Levomecol» ointment was used in the first group for sanation of omental bursae (lesser sac). The immobilized form of sodium hypochlorite was applied for the second group. RESULTS. Anti-inflammatory activity of immobilized form of sodium hypochlorite exceeded this activity in case of «Levomecol» application in 1,2-1,4 times. Anti-microbial activity was higher in 1,6-1,8 times at different terms of treatment of experimental animals. The proposed method of treatment of infected pancreatonecrosis allowed doctors to decrease the number of postoperative complications in patients on 11,2 % and lethality - on 9,2 %. CONCLUSIONS. It was stated that the application of immobilized forms of sodium hypochlorite for sanation of the omental bursae was pathogenically justified and efficient.

scholarly journals Anti-inflammatory and Anti-arthritic Potentials of Maesa Montana Roots

2021 ◽  
Vol 18 (16) ◽  
Author(s):  
Sanjida SHARMIN ◽  
Rabeya Gazi JHUMA ◽  
Sanjida ISLAM ◽  
Riniara KHATUN
Keyword(s):  
Bovine Serum ◽  
Protein Denaturation ◽  
Inflammatory Activity ◽  
Flowering Plant ◽  
Activity Measurement ◽  
Root Extract ◽  
Standard Drug ◽  
Activity Test ◽  
Anti Inflammatory

Maesa Montana is a flowering plant of the Myrsinaceae family, which is locally known as ramjani. The current study aimed to evaluate the in-vitro anti-arthritic and anti-inflammatory activities of the root extract of this plant. The anti-inflammatory performances were measured by the hindrance of egg white denaturation, and anti-arthritic activity was investigated by Bovine serum protein. In the anti-inflammatory activity test, the methanolic root extract of this plant showed 69.29 ± 1.19 % of inhibition at a concentration of 1000 µg/mL and standard drug exhibited 90.11 ± 1.45 % of inhibition at the same concentration. Furthermore, in the anti-arthritic activity test, the extract demonstrated 68.18 ± 1.34 % of inhibition at a concentration of 1000 µg/mL whereas the standard diclofenac drug showed 90.65 ± 1.19 % of inhibition at the same concentration. These results revealed that the root extract of this plant possesses significant anti-arthritic and anti-inflammatory activities based on the inhibition of BSA and protein denaturation. HIGHLIGHTS Methanol soluble compounds extraction from the roots of Maesa Montana Anti-inflammatory activity determination using egg albumin Anti-arthritic activity measurement using bovine serum albumin GRAPHICAL ABSTRACT

scholarly journals In vitro anti-inflammatory activity of mangrove plant Rhizophora mucronata Lam. (Malpighiales: Rhizophoraceae)

2018 ◽  
Vol 5 (10) ◽  
pp. 417-426 ◽  
Author(s):  
Samanjit Kaur ◽  
M. Syed Ali ◽  
V. Anuradha ◽  
V. Suganya ◽  
A. Ashashalini ◽  
...  
Keyword(s):  
Protein Denaturation ◽  
Inflammatory Activity ◽  
Bark Extract ◽  
Root Extract ◽  
Rhizophora Mucronata ◽  
Membrane Stabilization ◽  
In Vivo Models ◽  
Maximum Inhibition ◽  
Anti Inflammatory

In the present study, analysis of in vitro inflammatory showed whole plant of Rhizophora mucronata Lam. (Malpighiales: Rhizophoraceae) can be the potent source. The data from this study showed that the R. mucronata leaf, bark and root extract could serve as an important anti-inflammatory agent. Moreover, among the three extracts, the stilt root and leaves extract showed highest anti inflammatory. In vitro anti-inflammatory activity of the selected plant extracts was evaluated using albumin denaturation, membrane stabilization and proteinase inhibitory assays. As part of the investigation on the mechanism of the anti-inflammation activity, ability of extract protein denaturation was studied. Maximum inhibition (296.26%) was observed from root extract followed by bark (259.48%) and leaf (237.62%). The extracts inhibited the heat induced hemolysis of RBCs to varying degree as show in table below. The maximum inhibition 284.17% was observed from bark extract followed by root (265.05%) and leaf (232.61%). It reveals that these phytochemical constituents are responsible to maximum protection of protein denaturation, albumin denaturation and membrane stabilization assay. The future work will be determination of anti-inflammatory and anti-arthritic activities by in vivo models.

Anti-inflammatory activity of tea (Camellia sinensis) root extract

Life Sciences ◽  
2004 ◽  
Vol 74 (15) ◽  
pp. 1839-1849 ◽  
Author(s):  
P Chattopadhyay ◽  
S.E Besra ◽  
A Gomes ◽  
M Das ◽  
P Sur ◽  
...  
Keyword(s):  
Camellia Sinensis ◽  
Inflammatory Activity ◽  
Root Extract ◽  
Anti Inflammatory
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