scholarly journals Analgesic and anti-inflammatory activity of hydroalcoholic extract of Piper betle leaves in experimental animals

2016 ◽  
pp. 979-985 ◽  
Author(s):  
Pooja Reddy ◽  
Rajesh Gupta ◽  
Srikanth Reddy
Keyword(s):  
Inflammatory Activity ◽  
Piper Betle ◽  
Hydroalcoholic Extract ◽  
Experimental Animals ◽  
Anti Inflammatory

scholarly journals ASSESMENT OF ANTI-INFLAMMATORY ACTIVITY AND CYTOTOXICITY OF FREEZE DRIED HYDROALCOHOLIC EXTRACT OF Bidens andicola ON ISOLATED NEUTROPHILS

2017 ◽  
Vol 10 (6) ◽  
pp. 160
Author(s):  
Vinueza D ◽  
LÓpez E ◽  
Acosta K ◽  
Abdo S
Keyword(s):  
Freeze Drying ◽  
Water Soluble ◽  
Inflammatory Activity ◽  
Hydroalcoholic Extract ◽  
Cytotoxicity Assays ◽  
Aerial Parts ◽  
Controlled Conditions ◽  
Freeze Dried ◽  
Anti Inflammatory

Objective: The aim of this study was to evaluate anti-inflammatory activity and cytotoxicity in vitro of hydroalcoholic extract of Bidens andicola.Methods: B. andicola hydroalcoholic extract was obtained from aerial parts of B. andicola, following a standardized methodology. Briefly, aerial parts of B. andicola were extracted with ethanol 70% v/v and defatted with n-hexane, hydroalcoholic fraction was concentrated under controlled conditions in a rotary evaporator, and finally the residue was freeze-drying to obtain the hydroalcoholic extract of B. andicola. Anti-inflammatory activity and cytotoxicity assays were carried out using in vitro isolated neutrophils model using stable water-soluble tetrazolium salts.Results and Conclusions: The in vitro anti-inflammatory assay on isolated neutrophils demonstrated that the hydroalcoholic extract showed antiinflammatoryactivity compared to aspirin, with inflammatory inhibition percent values of 80.138±0.729 to hydroalcoholic extract of B. andicola and 82.117±0.762 to aspirin, each tested in five replicates at the concentration of 200 ppm of hydroalcoholic extract or reference. 

Evaluation of anti-inflammatory activity of Hydroalcoholic extract of Ananas cosmosus fruit peel by HRBC membrane stabilisation.

2018 ◽  
Vol 8 (1) ◽  
pp. 33
Author(s):  
Uma Sankar Gorla ◽  
M. Savithri ◽  
G.S.N. Koteswara Rao ◽  
Y. Niharika ◽  
P. Devi Sree Sathya ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Fruit Peel ◽  
Hydroalcoholic Extract ◽  
Anti Inflammatory

scholarly journals Anti-inflammatory activity and acute toxicity studies of hydroalcoholic extract of Herissantia tiubae

2016 ◽  
Vol 26 (2) ◽  
pp. 225-232 ◽  
Author(s):  
Ana L.A. Lima ◽  
Adriano F. Alves ◽  
Aline L. Xavier ◽  
Talissa Mozzini-Monteiro ◽  
Theresa R.R. Oliveira ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Inflammatory Activity ◽  
Hydroalcoholic Extract ◽  
Toxicity Studies ◽  
Anti Inflammatory

scholarly journals Experimental clinical substantiation of application of immobilized forms of sodium hypochlorite in treatment of infected pancreatonecrosis

2017 ◽  
Vol 176 (6) ◽  
pp. 32-37
Author(s):  
B. S. Sukovatykh ◽  
V. A. Zhukovskiy ◽  
Yu. Yu. Blinkov ◽  
A. I. Itinson ◽  
E. A. Elenskaya ◽  
...  
Keyword(s):  
Experimental Study ◽  
Postoperative Complications ◽  
Clinical Research ◽  
Microbial Activity ◽  
Sodium Hypochlorite ◽  
Inflammatory Activity ◽  
Experimental Animals ◽  
Lesser Sac ◽  
Anti Inflammatory

OBJECTIVE. The study substantiated the possibility of application of sodium hypochlorite for treatment of infected pancreatonecrosis. MATERIAL AND METHODS. The experimental study was conducted on 288 rats. Clinical research was carried out on 94 patients who were divided into two statistically homogenous groups. «Levomecol» ointment was used in the first group for sanation of omental bursae (lesser sac). The immobilized form of sodium hypochlorite was applied for the second group. RESULTS. Anti-inflammatory activity of immobilized form of sodium hypochlorite exceeded this activity in case of «Levomecol» application in 1,2-1,4 times. Anti-microbial activity was higher in 1,6-1,8 times at different terms of treatment of experimental animals. The proposed method of treatment of infected pancreatonecrosis allowed doctors to decrease the number of postoperative complications in patients on 11,2 % and lethality - on 9,2 %. CONCLUSIONS. It was stated that the application of immobilized forms of sodium hypochlorite for sanation of the omental bursae was pathogenically justified and efficient.

scholarly journals Anti-inflammatory activity of hydroalcoholic extract of mimosa pudica whole plant in rats

2017 ◽  
Vol 6 (3) ◽  
pp. 518
Author(s):  
Parvathy Velayudhan Nair ◽  
Bindu Latha R. Nair
Keyword(s):  
Inflammatory Activity ◽  
Toxicity Tests ◽  
Control Group ◽  
Albino Rats ◽  
Distilled Water ◽  
Mimosa Pudica ◽  
Hydroalcoholic Extract ◽  
Group I ◽  
Whole Plant ◽  
Anti Inflammatory

Background: Mimosa pudica is a traditionally used folk medicine to treat various disorders like infections, anxiety, depression, bleeding disorders, convulsions, rheumatoid arthritis, muscular pain, asthma, snake bite etc. We evaluated the anti-inflammatory activity of hydroalcoholic extract of Mimosa pudica whole plant (HAEMPWP) in rats.Methods: HAEMPWP was prepared using Soxhlets apparatus. Acute toxicity tests were done with HAEMPWP given orally to albino rats in increasing doses up to 3200 mg/ kg body weight. The anti-inflammatory action was evaluated by Carrageenan induced paw edema method. Thirty albino rats were grouped into five groups and each contained six rats. Group I (control group) received distilled water orally. Group II (standard) received Aspirin orally dissolved in distilled water. Groups III, IV and V received HAEMPWP in doses of 200 mg/kg, 400 mg/kg and 800mg/kg orally dissolved in distilled water. Data analysis was done by one way ANOVA and unpaired t test using SPSS 16 for windows.Results: HAEMPWP showed a significant anti-inflammatory activity as compared to control. There was no statistically significant dose dependent increase in the anti-inflammatory activity.Conclusions: HAEMPWP possesses significant anti-inflammatory activity and could be an effective treatment option for various inflammatory conditions.

scholarly journals Anti-inflammatory Potentials of Fibraurea tinctoria Leaves Extract in Experimental Rats or Animals

2020 ◽  
pp. 79-83
Author(s):  
Fahad I. Al-Saikhan
Keyword(s):  
Inflammatory Activity ◽  
Hydroalcoholic Extract ◽  
Percent Inhibition ◽  
Traditional Uses ◽  
Paw Oedema ◽  
Anti Inflammatory ◽  
Treatment Of Wounds

The activity of the hydroalcoholic extract of Fibraurea tinctoria leaves and anti-inflammatory was investigated. We utilized rats for which oedema was induced by carrageenan.  The extract of Fibraurea tinctoria leaves was administered orally at doses of 100, 200 and 400 mg/kg. Paw oedema was significantly minimized using all prepared doses of the extract administered. The 400 mg/kg dose producing the highest oedema reduction. The Percent Inhibition with hydroalcoholic extract of Fibraurea tinctoria and Indomethacin were 67.6% and 68.49% respectively. We concluded that this study has established the anti-inflammatory activity of hydroalcoholic extract of Fibraurea tinctoria leaves. I believe the results justify the traditional uses of the plant in the treatment of wounds and inflammation.

Evaluation of Phytochemical and Pharmacological Activity of Carissa carandas L. Fruits at Three Different Stages of Maturation

Drug Research ◽  
2019 ◽  
Vol 70 (02/03) ◽  
pp. 80-85
Author(s):  
Shabnam Saher ◽  
Smita Narnawre ◽  
Jayshree Patil
Keyword(s):  
Pharmacological Activity ◽  
Inflammatory Diseases ◽  
Acetone Extract ◽  
Inflammatory Activity ◽  
Traditional Use ◽  
Hydroalcoholic Extract ◽  
High Prevalence ◽  
Carissa Carandas ◽  
Consistent Increase ◽  
Anti Inflammatory

AbstractInflammation plays an important role in various diseases with high prevalence within populations such as rheumatoid arthritis, ulcer, atherosclerosis and asthma. Many drugs are available in the market for inflammatory diseases but they exhibit several unwanted side effects. Therefore, alternative treatments with safer compounds are needed. The plant Carissa carandas L. plant is used traditionally for the treatment of various diseases. Hence to validate its traditional use, the present study has envisaged screening different solvents extract of Carissa carandas fruit for their phytochemical and pharmacological activity especially the anti-inflammatory activity of the fruits at 3 different stages of maturation. The n-hexane and chloroform extracts of immature, mature and ripe fruits showed positive tests for steroids and triterpenoids, whereas acetone extract showed positive tests for steroids, triterpenoids, alkaloids, tannins, sugar, saponins except for triterpenoids in immature fruits. The hydroalcoholic extract showed presence of alkaloids, tannins, sugars, saponin and flavonoids. The highest concentration of phenol, flavonoids and ascorbic acid were found to be more in acetone extract of mature fruits and of carbohydrates in ripe fruits. The hydroalcoholic extract also exhibited similar pattern. The anti-inflammatory property was evaluated by using different models like carrageenan induced paw edema in Wistar rats and cotton pellets induced granuloma. There was a consistent increase in % inhibition of inflammation at concentrations of 100 and 200 mg/kg up to 3 h. The highest activity was at 3 h with 200 mg/kg dose. Thus the present work has clearly proved that the acetone extract of mature fruits have considerable anti-inflammatory activity.

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