Scutellarin and caffeic acid ester fraction, active components of Dengzhanxixin injection, upregulate neurotrophins synthesis and release in hypoxia/reoxygenation rat astrocytes

2013 ◽  
Vol 150 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Lijuan Chai ◽  
Hong Guo ◽  
Hui Li ◽  
Shaoxia Wang ◽  
Yu-lin Wang ◽  
...  
Keyword(s):  
Caffeic Acid ◽  
Acid Ester ◽  
Active Components ◽  
Ester Fraction ◽  
Rat Astrocytes ◽  
Fraction Active ◽  
Hypoxia Reoxygenation

Caffeic acid ester fraction from Erigeron breviscapus inhibits microglial activation and provides neuroprotection

2012 ◽  
Vol 18 (6) ◽  
pp. 437-444 ◽  
Author(s):  
Shao-xia Wang ◽  
Hong Guo ◽  
Li-min Hu ◽  
Ya-nan Liu ◽  
Yue-fei Wang ◽  
...  
Keyword(s):  
Caffeic Acid ◽  
Acid Ester ◽  
Microglial Activation ◽  
Ester Fraction ◽  
Erigeron Breviscapus

Cestric acid, a caffeic acid ester from Cestrum euanthes

1982 ◽  
Vol 21 (3) ◽  
pp. 743-746 ◽  
Author(s):  
Luc Nagels ◽  
Walter Van Dongen ◽  
Frits Parmentier
Keyword(s):  
Caffeic Acid ◽  
Acid Ester

scholarly journals Pharmacokinetics comparison of four major bio-active components in normal and blood stasis rats after administration of Naoxintong Capsule by UPLC-TQ/MS

2020 ◽  
Author(s):  
Wei-Xia Li ◽  
Pan-pan Chen ◽  
Shuqi Zhang ◽  
Man-man Li ◽  
Hui Zhang ◽  
...  
Keyword(s):  
Ferulic Acid ◽  
Caffeic Acid ◽  
Cold Water ◽  
Pathological Condition ◽  
Blood Stasis ◽  
Cerebrovascular Diseases ◽  
Tanshinone Iia ◽  
Pharmacokinetic Parameters ◽  
Active Components ◽  
Significant Difference

Abstract Background Blood stasis is one major cause of cardiovascular and cerebrovascular diseases. Naoxintong capsule (NXTC), a Chinese patent medicine, has been widely employed in the prevention and treatment against cardiovascular and cerebrovascular diseases. However, the pharmacokinetics comparison of NXTC in normal and blood stasis rats were remain obscured. Methods Acute blood stasis rats were induced by being placed in ice-cold water during the interval between two injections of adrenaline hydrochloride. Normal and blood stasis rats were administrated of NXTC suspension at the dosage of 5 g⋅kg -1 , and blood was collected at different time points after then. Concentrations of four main components including caffeic acid, ferulic acid, formononetin and tanshinone IIA in rat plasma were quantified by UPLC-TQ/MS. The pharmacokinetic parameters were calculated by Phoenix WinNonlin v6.2 software. Results It was found that C max , AUC all , AUC INF_obs , Vz_F_obs and MRT last of ferulic acid, AUC all, Vz_F_obs and MRT last of caffeic acid in blood stasis rats were significantly different ( P < 0.05) from normal rats. Compared with normal rats, C max of ferulic acid and formononetin decreased significantly in the plasma of acute blood stasis rats, AUC all of caffeic acid and ferulic acid decreased notably, AUC INF_obs of ferulic acid decreased remarkably, Vz_F_obs and MRT last of ferulic acid and caffeic acid increased reversely. It is suggested that the absorption of the four components of NXTC in acute blood stasis rats was weakened, and the elimination time was prolonged. Conclusions The significant difference in some different parameters of the 4 NXTC components in normal and blood stasis rats might be caused by increasing of blood viscosity and slowing down of blood flow in acute blood stasis rats. The pharmacokinetic study under pathological condition provided important information for more rational use of NXTC in clinical situations.

A caffeic acid ester from Halocnemum strobilaceum

1999 ◽  
Vol 51 (3) ◽  
pp. 465-467 ◽  
Author(s):  
Simon Gibbons ◽  
K.T. Mathew ◽  
Alexander I. Gray
Keyword(s):  
Caffeic Acid ◽  
Acid Ester ◽  
Halocnemum Strobilaceum

A new caffeic acid ester and a new ceramide from the roots of Eriosema glomeratum

2021 ◽  
Vol 45 ◽  
pp. 82-87
Author(s):  
Gaétan Tchangou Tabakam ◽  
Takeshi Kodama ◽  
Arno Rusel Nanfack Donfack ◽  
Yves Martial Mba Nguekeu ◽  
Battsengel Nomin-Erdene ◽  
...  
Keyword(s):  
Caffeic Acid ◽  
Acid Ester

Propolis allergy: synthesis and patch testing of γ,γ-dimethylallyl caffeic acid ester and its o-methyl derivatives

1989 ◽  
Vol 21 (4) ◽  
pp. 267-269 ◽  
Author(s):  
M Ginanneschi ◽  
M. C. Acciai ◽  
A. Sertoli ◽  
S. Bracci
Keyword(s):  
Caffeic Acid ◽  
Patch Testing ◽  
Acid Ester ◽  
Methyl Derivatives

scholarly journals Caffeic acid: a brief overview of its presence, metabolism, and bioactivity

2020 ◽  
Vol 3 (4) ◽  
pp. 74 ◽  
Author(s):  
Anna Birková
Keyword(s):  
Oxidative Stress ◽  
Chlorogenic Acid ◽  
Caffeic Acid ◽  
Acid Ester ◽  
Antioxidant Properties ◽  
Quinic Acid ◽  
Bioactive Compound ◽  
Common Phenomenon ◽  
Bioactive Substances ◽  
Naturally Occurring

Caffeic acid is a bioactive compound found in a variety of plants including vegetables, fruits, herbs, and drinks. It belongs to the huge group of chemicals called polyphenols and is a major representative of the polyphenol subgroup of hydroxycinnamic acids. In foods, caffeic acid occurs mostly as a quinic acid ester called chlorogenic acid. Caffeic acid, like other polyphenols, is believed to exhibit many health benefits associated with their antioxidant properties, including the prevention of inflammation, cancer, neurodegenerative diseases, and diabetes. Nowadays, the use of naturally occurring bioactive substances, including caffeic acid, is becoming a very common phenomenon. Thus, information about their functions and properties is very important.Keywords: caffeic acid, polyphenols, bioactive compound, oxidative stress

A caffeic acid ester mediates host recognition by a parasitic wasp

1993 ◽  
Vol 80 (2) ◽  
pp. 92-94 ◽  
Author(s):  
J. D. Hare ◽  
J. G. Millar ◽  
R. F. Luck
Keyword(s):  
Caffeic Acid ◽  
Acid Ester ◽  
Parasitic Wasp ◽  
Host Recognition
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