Complexation of As(III) by phosphonate ligands in aqueous fluids: Thermodynamic behavior, chemical binding forms and sequestering abilities

2020 ◽  
Vol 94 ◽  
pp. 100-110 ◽  
Author(s):  
Donatella Chillè ◽  
Donatella Aiello ◽  
Giuseppa Ida Grasso ◽  
Ottavia Giuffrè ◽  
Anna Napoli ◽  
...  
Keyword(s):  
Chemical Binding ◽  
Thermodynamic Behavior ◽  
Binding Forms ◽  
Phosphonate Ligands

Deposition patterns of iatrogenic lanthanum and gadolinium in the human body depend on delivered chemical binding forms

2021 ◽  
Vol 63 ◽  
pp. 126665
Author(s):  
Patrick Bücker ◽  
Henning Richter ◽  
Alexander Radbruch ◽  
Michael Sperling ◽  
Marcus Brand ◽  
...  
Keyword(s):  
Human Body ◽  
Chemical Binding ◽  
Deposition Patterns ◽  
Binding Forms

The Effect of Odor and Color on Chemical Cooling

2019 ◽  
Author(s):  
Robert Pellegrino ◽  
Curtis Luckett
Keyword(s):  
Primary Component ◽  
Magnitude Scale ◽  
Trigeminal System ◽  
Abstract Concepts ◽  
Specific Chemical ◽  
Chemical Binding ◽  
Cooling Intensity ◽  
Crossmodal Associations ◽  
First Session

Chemesthesis, along with taste and olfaction, is a primary component of flavor that engages the trigeminal system through specific chemical binding. For instance, many gums or confectionaries incorporate chemical cooling agents, such as Wilkinson Sword (WS) compounds, to create the sensation of coldness. The current study was designed to evaluate crossmodal associations of color and aroma with the chemesthetic perception of cooling. A “minty” and non-odorized set of confectionary stimuli, colored green, blue or white, with moderate cooling properties (with WS-3) were used in this study. In the first session, participants were randomly presented a stimuli and asked to rate several attributes including its cooling intensity on a generalized Labeled Magnitude Scale (gLMS). In the second session, the same participants were asked to relate cooling levels to different colors and which color relates to the “minty” odor. Additionally, open-ended reasons were given for association choices. Appearance and odor influenced the intensity of cooling sensation. In particular, the odorized and blue samples were rated as cooler than the non-odorized and other colored samples, respectively. The follow-up session confirms blue as a color associated with cooling properties, especially cool objects/abstract concepts. Meanwhile, odor’s enhancement on cooling sensation may be more perceptual in nature through affective matching from enhanced flavor.

scholarly journals Coronavirus and Soft Law in Germany: Business as Usual?

2021 ◽  
pp. 1-17
Author(s):  
Matthias Knauff
Keyword(s):  
Legal Order ◽  
Soft Law ◽  
Constitutional Order ◽  
Binding Forms ◽  
Almost All ◽  
Business As Usual ◽  
Shed Light ◽  
Made In

In combating the coronavirus pandemic in Germany, soft law has played an important, albeit not a central, role. Its use basically corresponds to that of under “normal circumstances”. In accordance with the German constitutional order, almost all substantial decisions are made in a legally binding form. However, these are often prepared through or supplemented by soft law. This article shows that soft law has played an important role in fighting the pandemic and its effects in Germany, although there cannot be any doubt that legally binding forms of regulation have prevailed. At the same time, the current pandemic has shed light on the advantages and effects of soft law in the context of the German legal order.

Small-angle electron scattering by formaldehyde and ketene: Effects of electron correlation and chemical binding

1992 ◽  
Vol 43 (5) ◽  
pp. 701-712 ◽  
Author(s):  
Yorihiko Sasaki ◽  
Hiroshi Takeuchi ◽  
Shigehiro Konaka ◽  
Masao Kimura
Keyword(s):  
Electron Scattering ◽  
Small Angle ◽  
Electron Correlation ◽  
Chemical Binding

scholarly journals Transformation of the aryl hydrocarbon receptor to a DNA-binding form is accompanied by release of the 90 kDa heat-shock protein and increased affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin

1993 ◽  
Vol 294 (1) ◽  
pp. 95-101 ◽  
Author(s):  
E C Henry ◽  
T A Gasiewicz
Keyword(s):  
Heat Shock ◽  
Dna Binding ◽  
Heat Shock Protein ◽  
Aryl Hydrocarbon Receptor ◽  
Incubation Temperature ◽  
Binding Affinities ◽  
Aryl Hydrocarbon ◽  
Molecular Events ◽  
Binding Forms ◽  
Tetrachlorodibenzo P Dioxin

The binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to the aryl hydrocarbon receptor (AhR) elicits a sequence of poorly defined molecular events that ultimately yield a heteromeric transformed AhR that is active as a transcription factor. We have previously developed a model of the ligand-initiated transformation of the AhR to the DNA-binding state based on characterization of several forms of the AhR with respect to their physicochemical properties and DNA-binding affinities. The present studies were designed to determine whether, and at what stage, this process of transformation alters the receptor's affinity for TCDD. In rat hepatic cytosol, approx. 10% of the TCDD specifically bound to the AhR rapidly dissociated (t1/2 approximately 1 h), while the remainder was only slowly dissociable (t1/2 approximately 70 h). The isolated DNA-binding forms of the receptor (monomeric and transformed) bound TCDD very tightly (t1/2 > 100 h), whereas TCDD was dissociable from the non-DNA-binding receptor form(s). A lower incubation temperature (0-4 degrees C) and the presence of molybdate partially stabilized the non-DNA-binding fraction of the TCDD.receptor complex and also enhanced TCDD dissociation in crude cytosol. Immunoprecipitation of the different AhR forms with an anti-AhR antibody and immunoblotting with antibody to the 90 kDa heat-shock protein (hsp90) demonstrated that hsp90 was associated with the unoccupied receptor complex as well as with a fraction of the non-DNA-binding TCDD.receptor complex; isolated DNA-binding forms did not contain detectable hsp90. We conclude that while hsp90 remains associated with the AhR, TCDD is readily dissociable; following release of hsp90, however, TCDD becomes very tightly bound, and remains so upon completion of transformation.

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