Bordetella are small Gram-negative coccobacilli, of which Bordetella pertussis is the most important human pathogen. It is the cause of whooping cough, which is one of the 10 leading causes of childhood death. Transmission of this highly infectious organism is primarily by aerosolized droplets.
Clinical features—presentation varies with age, immunization and previous infection: (1) infants—apnoea, cyanosis, and paroxysmal cough; (2) nonimmunized children—cough, increasing in severity with distressing, repeated, forceful expirations followed by a gasping inhalation (the ‘whoop’); (3) children immunized in infancy—whooping, vomiting, sputum production; (4) adults—cough, post-tussive vomiting. Atypical mild illness is common. Complications include pneumonia, pulmonary hypertension, seizures and encephalopathy. Most deaths occur in those less than 2 months old....
Necrotic Skin Infection by Sphingomonas Paucimobilis in Amazonia Region