Pb(II)-binding capability of aminohydroxamic acids: Primary hydroxamic acid derivatives of α-amino acids as possible sequestering agents for Pb(II)

A new side-product, succinohydroxamic decanoic anhydride, was isolated from the reaction mixture during the acylation of lysine by succinimidyl decanoate in the presence of aqueous sodium hydroxide. Laurie and palmitic acid derivatives were also obtained. It is shown that these compounds can be used for acylation of amino acids. The hydroxamic acid derivatives were also detected when the acylations by succinimidyl esters of fatty acids were carried out under anhydrous conditions. Preparation of N-lauroyl-L-tyrosine methyl ester from tyrosine methyl ester and succinimidyl laurate is also described.

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ChemInform Abstract: METHOTREXATE ANALOGS. 13. CHEMICAL AND PHARMACOLOGICAL STUDIES ON AMIDE, HYDRAZIDE, AND HYDROXAMIC ACID DERIVATIVES OF THE GLUTAMATE SIDE CHAIN

Chemischer Informationsdienst ◽

10.1002/chin.198144220 ◽

1981 ◽

Vol 12 (44) ◽

Author(s):

A. ROSOWSKY ◽

CH.-S. YU ◽

J. UREN ◽

H. LAZARUS ◽

M. WICK

Keyword(s):

Hydroxamic Acid ◽

Side Chain ◽

Pharmacological Studies ◽

Derivatives Of ◽

Hydroxamic Acid Derivatives

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New insights into the metal ion–peptide hydroxamate interactions: Metal complexes of primary hydroxamic acid derivatives of common dipeptides in aqueous solution

Polyhedron ◽

10.1016/j.poly.2006.12.014 ◽

2007 ◽

Vol 26 (8) ◽

pp. 1625-1633 ◽

Cited By ~ 21

Author(s):

Péter Buglyó ◽

Eszter Márta Nagy ◽

Etelka Farkas ◽

Imre Sóvágó ◽

Daniele Sanna ◽

...

Keyword(s):

Aqueous Solution ◽

Metal Complexes ◽

Metal Ion ◽

Hydroxamic Acid ◽

Derivatives Of ◽

Hydroxamic Acid Derivatives

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Hydroxamic acids. III. Mass spectra of substituted hydroxamic acids and cyclic imides

Australian Journal of Chemistry ◽

10.1071/ch9690175 ◽

1969 ◽

Vol 22 (1) ◽

pp. 175 ◽

Cited By ~ 14

Author(s):

JH Bowie ◽

MTW Hearn ◽

AD Ward

Keyword(s):

Electron Impact ◽

Hydroxamic Acid ◽

Mass Spectra ◽

Hydroxamic Acids ◽

Skeletal Rearrangement ◽

Cyclic Imides ◽

Derivatives Of ◽

Hydroxamic Acid Derivatives

Aryl hydroxamic acid derivatives fragment in a diagnostic manner upon electron impact. A hydroxamic acid containing both styryl and benzyl substituents undergoes skeletal-rearrangement of the type ABC → AC+B. The mass spectra of the O- and N-acetyl derivatives of O- benzylhydroxamic acids are indistinguishable. M-CO2 fragments are again observed in the mass spectra of several substituted phthalimides.

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Acyl derivatives of Hydroxylamine. XIII. Configuration and conformation of hydroxamic acid derivatives containing sulfur

Canadian Journal of Chemistry ◽

10.1139/v68-311 ◽

1968 ◽

Vol 46 (11) ◽

pp. 1873-1880 ◽

Cited By ~ 12

Author(s):

O. Exner ◽

M. H. Benn ◽

Frances Willis

Keyword(s):

Magnetic Resonance ◽

Hydroxamic Acid ◽

Proton Magnetic Resonance ◽

Dipole Moments ◽

Electronic Nature ◽

Graphical Comparison ◽

Derivatives Of ◽

Configuration And Conformation ◽

Acyl Derivatives ◽

Hydroxamic Acid Derivatives

The configurations and conformations of S-methyl benzothiohydroxamic acid (3) and its S-oxo and S,S-dioxo derivatives (5) and (7) were established by means of a graphical comparison of their dipole moments with those of the corresponding p-nitro compounds.The proton magnetic resonance and infrared spectra of these compounds were also studied.It is concluded that the relative stability of stereoisomers in the series of compounds C6H5C(NOH)X seems to depend more on the electronic nature of the group X than on its steric requirements.

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