Clustering and Halogen Effects Enabled Red/Near-Infrared Room Temperature Phosphorescence from Aliphatic Cyclic Imides

<a>Pure organics with room temperature phosphorescence (RTP) are urgently demanded in advanced optoelectronic and bioelectronic applications. However, currently reported phosphors are mostly aromatics and restricted to blue to orange colors. It remains an enormous challenge to achieve red and near-infrared (NIR) RTP, particularly for those from nonaromatics. Here we demonstrate a series of cyclic imides derived from succinimide, which can emit red (665, 690 nm) and even NIR (745 nm) RTP with outstanding efficiencies of up to 9.2%, despite their rather limited molecular conjugations. Such unique emission should be ascribed to the presence of the imide unit and heavy atoms, effective molecular clustering, and the electron delocalization of halogens, which not only greatly facilitate intersystem crossing, but also afford significantly extended through-space conjugation and rigidified conformations.</a> These results pave the way to the rational construction of red and NIR nonconventional luminophores through synergistic clustering and halogen effects.

Design, Synthesis and Antibacterial Activity screening of Novel Bis cyclic Imides Linked to Trimethoprim Drug

Cyclic imides are well known important organic compounds that exhibit diverse biological activities like anti - inflammatory, antibacterial, analgesic, hypoglycemic and antifungal activities. Besides these compounds are useful building blocks in the synthesis of many drugs and pharmaceuticals. On the other hand trimethoprim is a well-known antibiotic that is used in combination with Sulfamethoxazole in treating urinary tract infections, bacterial infections and acute invasive diarrhea. Moreover Schiff bases represent the most active intermediates that exhibit wide spectrum of biological activities and play a vital role in the production of different pharmaceutical and bioactive heterocycles. Based on all these facts, it seems worthwhile to design and synthesize new molecules that contain these three active moieties (cyclic imide, trimethoprim and Schiff base) together in the same molecule since this may exhibit the new compounds high biological activity and may open possibilities for fighting bacterial infections.

Clustering and Halogen Effects Enabled Red/Near-Infrared Room Temperature Phosphorescence from Aliphatic Cyclic Imides

<a>Pure organics with room temperature phosphorescence (RTP) are urgently demanded in advanced optoelectronic and bioelectronic applications. However, currently reported phosphors are mostly aromatics and restricted to blue to orange colors. It remains an enormous challenge to achieve red and near-infrared (NIR) RTP, particularly for those from nonaromatics. Here we demonstrate a series of cyclic imides derived from succinimide, which can emit red (665, 690 nm) and even NIR (745 nm) RTP with outstanding efficiencies of up to 9.2%, despite their rather limited molecular conjugations. Such unique emission should be ascribed to the presence of the imide unit and heavy atoms, effective molecular clustering, and the electron delocalization of halogens, which not only greatly facilitate intersystem crossing, but also afford significantly extended through-space conjugation and rigidified conformations.</a> These results pave the way to the rational construction of red and NIR nonconventional luminophores through synergistic clustering and halogen effects.

Clustering and Halogen Effects Enabled Red/Near-Infrared Room Temperature Phosphorescence from Aliphatic Cyclic Imides

<a>Pure organics with room temperature phosphorescence (RTP) are urgently demanded in advanced optoelectronic and bioelectronic applications. However, currently reported phosphors are mostly aromatics and restricted to blue to orange colors. It remains an enormous challenge to achieve red and near-infrared (NIR) RTP, particularly for those from nonaromatics. Here we demonstrate a series of cyclic imides derived from succinimide, which can emit red (665, 690 nm) and even NIR (745 nm) RTP with outstanding efficiencies of up to 9.2%, despite their rather limited molecular conjugations. Such unique emission should be ascribed to the presence of the imide unit and heavy atoms, effective molecular clustering, and the electron delocalization of halogens, which not only greatly facilitate intersystem crossing, but also afford significantly extended through-space conjugation and rigidified conformations.</a> These results pave the way to the rational construction of red and NIR nonconventional luminophores through synergistic clustering and halogen effects.

Highly Chemoselective Hydrogenation of Cyclic Imides to ω-hydroxylactams or ω-hydroxyamides Catalyzed by Iridium Catalysts

Several novel Ferrocene-based PNN ligands were prepared, which were found as highly effective catalysts (TON up to 50,000) in the homogeneous hydrogenation of cyclic imides with Iridium. The hydrogenation mode...

Cu-catalyzed C(sp2)-N-bond coupling of boronic acids and cyclic imides

A general Cu-catalyzed strategy for coupling cyclic imides and alkenylboronic acids by forming C(sp2)-N-bonds is reported. The method enables the practical and mild preparation of enimides. A large range of...