Interactions of copper and copper chelate compounds with the amyloid beta peptide: An investigation into electrochemistry, reactive oxygen species and peptide aggregation

2021 ◽  
pp. 111493
Author(s):  
Emma Crnich ◽  
Rachel Lullo ◽  
Amber Tabaka ◽  
Mallory A. Havens ◽  
Daniel S. Kissel
Keyword(s):  
Reactive Oxygen Species ◽  
Amyloid Beta ◽  
Reactive Oxygen ◽  
Amyloid Beta Peptide ◽  
Peptide Aggregation ◽  
Oxygen Species ◽  
Copper Chelate ◽  
Beta Peptide ◽  
Chelate Compounds

scholarly journals A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation

2019 ◽  
Vol 10 (6) ◽  
pp. 1634-1643 ◽  
Author(s):  
Luiza M. F. Gomes ◽  
Atif Mahammed ◽  
Kathleen E. Prosser ◽  
Jason R. Smith ◽  
Michael A. Silverman ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Reactive Oxygen Species ◽  
Amyloid Beta ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Amyloid Beta Peptide ◽  
Peptide Aggregation ◽  
Oxygen Species ◽  
Beta Peptide ◽  
Catalytic Antioxidant

An Fe corrole is shown to bind to the amyloid-beta peptide and limit reactive oxygen species generation and peptide aggregation of relevance to Alzheimer's disease.

scholarly journals HIV-Tat Protein Enhances Amyloid Beta Peptide Aggregation

2014 ◽  
Vol 106 (2) ◽  
pp. 683a
Author(s):  
Alina Popescu Hategan ◽  
Joseph Steiner ◽  
Emilios K. Dimitriadis ◽  
Avindra Nath
Keyword(s):  
Amyloid Beta ◽  
Amyloid Beta Peptide ◽  
Peptide Aggregation ◽  
Tat Protein ◽  
Hiv Tat ◽  
Beta Peptide ◽  
Hiv Tat Protein

scholarly journals Curcumin-like compounds designed to modify amyloid beta peptide aggregation patterns

RSC Advances ◽  
2017 ◽  
Vol 7 (50) ◽  
pp. 31714-31724 ◽  
Author(s):  
Antonella Battisti ◽  
Antonio Palumbo Piccionello ◽  
Antonella Sgarbossa ◽  
Silvia Vilasi ◽  
Caterina Ricci ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Beta ◽  
Amyloid Beta Peptide ◽  
Peptide Aggregation ◽  
New Concepts ◽  
Novel Drugs ◽  
Beta Peptide

This study suggests new concepts and potential difficulties in the design of novel drugs against diverse amyloidoses, including Alzheimer’s disease.

In vitro reconstitution of a cell-like environment using liposomes for amyloid beta peptide aggregation and its propagation

2013 ◽  
Vol 49 (55) ◽  
pp. 6119 ◽  
Author(s):  
Abhijit Saha ◽  
Goutam Mondal ◽  
Atanu Biswas ◽  
Indrani Chakraborty ◽  
Batakrishna Jana ◽  
...  
Keyword(s):  
Amyloid Beta ◽  
Amyloid Beta Peptide ◽  
Peptide Aggregation ◽  
In Vitro Reconstitution ◽  
Beta Peptide ◽  
A Cell

Copper(II) mixed chelate compounds induce apoptosis through reactive oxygen species in neuroblastoma cell line CHP-212

2013 ◽  
Vol 126 ◽  
pp. 17-25 ◽  
Author(s):  
Anllely Grizett Gutiérrez ◽  
Adriana Vázquez-Aguirre ◽  
Juan Carlos García-Ramos ◽  
Marcos Flores-Alamo ◽  
Enrique Hernández-Lemus ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cell Line ◽  
Neuroblastoma Cell ◽  
Reactive Oxygen ◽  
Neuroblastoma Cell Line ◽  
Oxygen Species ◽  
Chelate Compounds
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