scholarly journals Moving Ru polypyridyl complexes beyond cytotoxic activity towards metastasis inhibition

2021 ◽  
pp. 111652
Author(s):  
Małgorzata Brindell ◽  
Ilona Gurgul ◽  
Ewelina Janczy-Cempa ◽  
Przemysław Gajda-Morszewski ◽  
Olga Mazuryk
Keyword(s):  
Cytotoxic Activity ◽  
Polypyridyl Complexes ◽  
Metastasis Inhibition

Dinuclear ruthenium(II) polypyridyl complexes: Mechanistic study with biomolecules, DNA/BSA interactions and cytotoxic activity

Polyhedron ◽  
2020 ◽  
Vol 178 ◽  
pp. 114334 ◽  
Author(s):  
Milica Medjedović ◽  
Ana Rilak Simović ◽  
Dušan Ćoćić ◽  
Milan Milutinović ◽  
Laura Senft ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Mechanistic Study ◽  
Polypyridyl Complexes ◽  
Dinuclear Ruthenium

Evaluation of anticancer activity in vitro and in vivo of iridium(iii) polypyridyl complexes

2019 ◽  
Vol 43 (22) ◽  
pp. 8566-8579 ◽  
Author(s):  
Miao He ◽  
Qiao-Yan Yi ◽  
Wen-Yao Zhang ◽  
Lan Bai ◽  
Fan Du ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Membrane Potential ◽  
Cytotoxic Activity ◽  
Anticancer Activity ◽  
Cell Cycle Arrest ◽  
Mitochondrial Membrane ◽  
Polypyridyl Complexes ◽  
Cycle Arrest

Three new iridium(iii) polypyridyl complexes were synthesized. The cytotoxic activity in vitro and in vivo, apoptosis, cell cycle arrest, mitochondrial membrane potential, ROS and the expression of Bcl-2 family proteins were investigated.

scholarly journals Synthesis, Characterization, Cytotoxic Activity, and Metabolic Studies of Ruthenium(II) Polypyridyl Complexes Containing Flavonoid Ligands

2020 ◽  
Vol 59 (7) ◽  
pp. 4424-4434 ◽  
Author(s):  
Alexandra-Cristina Munteanu ◽  
Anna Notaro ◽  
Marta Jakubaszek ◽  
Joseph Cowell ◽  
Mickaël Tharaud ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Polypyridyl Complexes ◽  
Metabolic Studies

Water-soluble amphiphilic ruthenium(ii) polypyridyl complexes as potential light-activated therapeutic agents

2020 ◽  
Vol 56 (65) ◽  
pp. 9332-9335
Author(s):  
Sandra Estalayo-Adrián ◽  
Salvador Blasco ◽  
Sandra A. Bright ◽  
Gavin J. McManus ◽  
Guillermo Orellana ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Cells ◽  
Cellular Uptake ◽  
Therapeutic Agents ◽  
Water Soluble ◽  
Polypyridyl Complexes ◽  
Cervical Cancer Cells

Two new water-soluble amphiphilic Ru(ii) polypyridyl complexes were synthesised and their photophysical and photobiological properties evaluated; both complexes showed a rapid cellular uptake and phototoxicity against HeLa cervical cancer cells.

Phytochemical characterization and cytotoxic activity of Iranecio elbursensis Bioss.

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
L Shafiee Hanjani ◽  
P Yazdizadeh Shotorbani ◽  
T Asgari ◽  
G Amin ◽  
E Azizi
Keyword(s):  
Cytotoxic Activity

Unusual Cycloartane Saponins with Cytotoxic Activity from Astragalus stereocalyx Bornm.

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
FN Yalçın ◽  
S Piacente ◽  
A Perrone ◽  
A Capasso ◽  
H Duman ◽  
...  
Keyword(s):  
Cytotoxic Activity

Screening of Venezuelan medicinal plant extracts for cytostatic and cytotoxic activity against tumour cell lines

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
P Taylor ◽  
M Arsenak ◽  
MJ Abad ◽  
Á Fernández ◽  
R Gonto ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Plant Extracts ◽  
Tumour Cell ◽  
Medicinal Plant Extracts ◽  
Tumour Cell Lines
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