Mini-resectoscopy Endometrial Biopsy Accuracy Respect Dilatation and Curettage in Endometrial Cancer: A Retrospective Analysis

2021 ◽  
Vol 28 (11) ◽  
pp. S45
Author(s):  
G.M. Miele ◽  
K. Cefalì ◽  
P. Manna ◽  
C. di Carlo ◽  
F. Zullo
Keyword(s):  
Endometrial Cancer ◽  
Retrospective Analysis ◽  
Endometrial Biopsy ◽  
Dilatation And Curettage

Hysteroscopy and Endometrial Cancer Diagnosis: A Review of 2007 Consecutive Examinations in Self-Referred Patients

1991 ◽  
Vol 77 (6) ◽  
pp. 479-483 ◽  
Author(s):  
Anna lossa ◽  
Luciano Cianferoni ◽  
Stefano Ciatto ◽  
Silvia Cecchini ◽  
Carlo Campatelli ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Cancer Detection ◽  
Detection Rate ◽  
Uterine Cancer ◽  
Abnormal Uterine Bleeding ◽  
Cost Effective ◽  
Endometrial Biopsy ◽  
Cancer Detection Rate ◽  
Dilatation And Curettage ◽  
Rule Out

The authors reviewed 2007 consecutive outpatient hysteroscopies performed in self-referred women to assess the detection rate of uterine cancer and the validity of different selection criteria for hysteroscopy. Thirty cases of uterine cancer (29 endometrial, 1 carcinosarcoma) were detected. Abnormal uterine bleeding was the indication most commonly associated with cancer (26 of 30 cases, cancer detection rate = 2.1 %), whereas the presence of cervical polyps had no predictive value. Patients age was correlated to cancer detection rate, and the investigation of uterine cancer under the age of 45 was poorly cost effective. Hysteroscopy and endometrial biopsy, performed by Permacurette or Novak curette immediately after hysteroscopy, missed respectively 8 and 2 of 30 cancers. Hysteroscopy should be employed in combination with endometrial biopsy as a standard outpatient investigation whenever endometrial cancer is suspected. These procedures are safe and accurate and rule out more aggressive and costly procedures, such as dilatation and curettage, in most cases.

Should Preoperative Pathology Be Used to Select Patients for Surgical Staging in Endometrial Cancer?

2009 ◽  
Vol 19 (3) ◽  
pp. 380-384 ◽  
Author(s):  
Julie A. Francis ◽  
Michele M. Weir ◽  
Helen C. Ettler ◽  
Feng Qiu ◽  
Janice S. Kwon
Keyword(s):  
Endometrial Cancer ◽  
Outcome Measure ◽  
Endometrial Biopsy ◽  
Surgical Staging ◽  
Teaching Hospitals ◽  
Endometrioid Adenocarcinoma ◽  
Final Pathology ◽  
Dilatation And Curettage ◽  
Preoperative Biopsy ◽  
Significant Difference

Introduction:The decision to offer surgical staging in endometrial cancer is often based on preoperative histology and grade from endometrial biopsy or dilatation and curettage. The primary objective of this study was to evaluate the concordance between preoperative and final pathology from a population-based study of endometrial cancer to address whether preoperative biopsy is a reliable determinant in selecting patients for surgical staging.Methods:Retrospective cohort study in Ontario, Canada, from 1996 to 2000. The study included all women with a preoperative diagnosis of endometrioid adenocarcinoma on endometrial biopsy or dilatation and curettage, followed by definitive surgery. All other histological types were excluded. Surgical staging rates were compared according to preoperative pathology. Primary outcome measure was the concordance between preoperative and final pathology, expressed as a Spearman correlation coefficient (ρ). A multivariable logistic regression estimated the effects of demographic variables and grade on our outcome measure.Results:There were 1804 evaluable cases in this study. For preoperative grades 1, 2, and 3 endometrioid adenocarcinoma, surgical staging rates were 9.1%, 13.7%, and 25.6%, respectively. Concordance rates with final pathology were 73%, 52%, and 53%, respectively. There was only moderate concordance between preoperative and final pathology (ρ = 0.52). There was no significant difference in concordance rates according to age, year, or hospital volume, but lower concordance rates among teaching hospitals.Conclusion:Preoperative biopsy has only a moderate ability to predict final pathology in endometrial cancer, and therefore, additional factors should be considered in selecting patients for a surgical staging procedure.

scholarly journals Comparison of preoperative endometrial biopsy grade and final pathologic diagnosis in patients with endometrioid endometrial cancer

2012 ◽  
Vol 13 (2) ◽  
pp. 106-110 ◽  
Author(s):  
Behiye Pinar Cilesiz Goksedef ◽  
Ozgur Akbayir ◽  
Aytul Corbacioglu ◽  
Hakan Guraslan ◽  
Fatmagul Sencan ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Endometrial Biopsy ◽  
Pathologic Diagnosis ◽  
Endometrioid Endometrial Cancer

scholarly journals Preoperative and intraoperative assesment of myometrial invasion and histological grade in endometrial cancer: Role of MRI and frozen section

2016 ◽  
Author(s):  
Rohit Raghunath Ranade
Keyword(s):  
Endometrial Cancer ◽  
Tumor Size ◽  
Early Stage ◽  
Frozen Section ◽  
Myometrial Invasion ◽  
Tumor Grade ◽  
Endometrial Biopsy ◽  
Intraoperative Frozen Section ◽  
Cervical Involvement

Introduction: The role of systematic lymphadenectomy in clinically early stage endometrial cancer is controversial. A number of factors can predict lymph node metastasis including myometrial invasion, tumor grade in endometrial cancers. The purpose of the present study is to evaluate the accuracy of preoperative MRI and intraoperative frozen section in determining the depth of myometrial invasion, cervical involvement, tumor size and lymph nodal status. We also studied the accuracy of preoperative endometrial biopsy and intraoperative frozen section in determining the grade of the tumor. Materials and Methods: Medical records of 235 consecutive cases of clinically early stage endometrial cancer were reviewed retrospectively. A record of depth of myometrial invasion, tumor size, cervical involvement and presence of enlarged lymph nodes was made on a preoperative MRI. Similarly depth of myometrial invasion, tumor size, cervical involvement and grade of the tumor were recorded on an intraoperative frozen section. The grade of the tumor was also recorded on a preoperative endometrial biopsy. Standard statistical calculations were used. Results: The sensitivity and specificity of MRI for myometrial invasion for the first 160 cases were 81.3 and 75%, respectively while that for frozen section were 80 and 96.2%, respectively. For tumor grade the sensitivity and specificity of preoperative endometrial biopsy were 60 and 95.6%, respectively while that of frozen section were 53.8 and 97.6%, respectively. For cervical involvement the sensitivity of MRI and frozen section was 62.5 and 98.4%, respectively. Updated results of the entire cohort of 235 cases will be presented at the conference if selected. Conclusion: Although the sensitivity of both frozen section and MRI for predicting deep myometrial invasion was similar (80 vs 81.3%) but the specificity (96.2 vs 75%) and negative predictive value (92.7 vs 88.2%) of frozen section were superior to MRI. Both preoperative biopsy and intraoperative frozen section had low sensitivity (60 vs 53.8%) for detecting a high grade lesion.

scholarly journals Cancer Endometrium: An Update

2012 ◽  
Vol 4 (2) ◽  
pp. 75-84 ◽  
Author(s):  
Piyush Kumar ◽  
Jai Kishan Goel
Keyword(s):  
Endometrial Cancer ◽  
Gynecological Cancer ◽  
Preoperative Staging ◽  
Abnormal Uterine Bleeding ◽  
Developed Countries ◽  
Endometrial Biopsy ◽  
External Beam Radiation ◽  
Beam Radiation ◽  
Estrogen Exposure ◽  
Cardinal Symptom

ABSTRACT Endometrial cancer is the most common gynecological cancer in developed countries and second most common in developing countries. Its incidence is increasing in postmenopausal women. Factors related to chronic estrogen exposure are associated with a higher incidence. Abnormal uterine bleeding is the cardinal symptom. All women with suspected endometrial cancer require transvaginal ultrasonography and most will undergo endometrial biopsy; more sophisticated radiological examinations are required for preoperative staging. The general approach for treatment of endometrial cancer is hysterectomy, bilateral salpingo-oophorectomy, abdominopelvic washings, lymph node evaluation and maximal surgical cytoreduction for those with advanced disease. Postoperative adjuvant therapy [vaginal brachytherapy, external beam radiation therapy (RT), chemotherapy] may be recommended depending on the estimated risk of recurrence. Individual patient characteristics and surgical as well as pathologic staging are the main factors that are used for postsurgical risk stratification, which in turn, directs the selection of adjuvant treatment. How to cite this article Goel JK, Kumar P. Cancer Endometrium: An Update. J South Asian Feder Obst Gynae 2012;4(2):75-84.

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