Folate and Iron Status Do Not Differ Between Women of Childbearing Age Following Gluten-Free and Conventional Diets

Abstract This paper examines the current state of the blood supply in the US and focuses on the potential for augmenting blood availability by attention to the iron status of donors. Increasing demands are being made upon the national blood supply as rates of blood donation are declining, in part because of the loss of blood donors as a result of enhanced screening and testing procedures. Iron-related means of expanding the blood supply include the use of blood from individuals undergoing therapeutic phlebotomy for hereditary hemochromatosis and enhancing the retention and commitment of women of childbearing age as donors by using iron supplementation to prevent iron deficiency. In Section I, Dr. Klein discuss the circumstances responsible for a decline in the population of eligible donors, including public attitudes toward donation, factors influencing the retention of donors by blood centers, and the effects of increased screening and testing to maintain the safety of the blood supply. In Section II, Drs. Kushner and Ajioka focus on the consequences of the decision by the US Food and Drug Administration (FDA) to develop recommendations to permit blood centers to collect blood from patients with hereditary hemochromatosis and to distribute this blood obtained without disease labeling if all other screening and testing procedures are passed. After summarizing the pathophysiology of hereditary hemochromatosis, the use by blood centers of blood obtained from heterozygotes and homozygotes for hereditary hemochromatosis is considered. In Section III, Dr. Brittenham reviews the use of low dose, short-term carbonyl iron supplementation for women donors of childbearing age. Replacing the iron lost at donation can help prevent iron deficiency in women of childbearing age and, by decreasing deferral, enhance the retention and commitment of women who give blood regularly. He emphasizes the use by blood centers of iron-related means to enhance recruitment and retention of blood donors.

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The impact of a meat- versus a vegetable-based diet on iron status in women of childbearing age with small iron stores

European Journal of Nutrition ◽

10.1007/s00394-007-0683-6 ◽

2007 ◽

Vol 46 (8) ◽

pp. 439-445 ◽

Cited By ~ 16

Author(s):

Inge Tetens ◽

Karen M. Bendtsen ◽

Marianne Henriksen ◽

Annette K. Ersbøll ◽

Nils Milman

Keyword(s):

Iron Status ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Iron Stores ◽

The Impact

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Low prevalence of iron deficiency anemia between 1981 and 2010 in Chilean women of childbearing age

Salud Pública de México ◽

10.21149/spm.v55i5.7247 ◽

2013 ◽

Vol 55 (5) ◽

pp. 478 ◽

Cited By ~ 6

Author(s):

Israel Ríos-Castillo ◽

Alex Brito ◽

Manuel Olivares ◽

Daniel López-de Romaña ◽

Fernando Pizarro

Keyword(s):

Iron Deficiency ◽

Iron Deficiency Anemia ◽

Iron Status ◽

Transferrin Saturation ◽

Deficiency Anemia ◽

Zinc Protoporphyrin ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Prevalence Of Anemia ◽

Chilean Women

Objective. To determine the prevalence of anemia and iron status among Chilean women of childbearing age between 1981 and 2010. Materials and methods. Calculation of the prevalence of anemia and iron status was based on multiple cross-sectional iron absorption studies performed in 888 women during this period of time. All studies included measurements of hemoglobin, mean corpuscular volume, zinc protoporphyrin, percentage of transferrin saturation and serum ferritin. Data were grouped by decade (1981-1990, 1991-2000, and 2001-2010). Results. Prevalence of anemia for these decades was 9, 6 and 10%, respectively (p=NS). Iron deficiency anemia was the main cause of anemia in all periods (55, 85 and 75%, respectively; p=NS). A high prevalence of women with normal iron status was observed for all periods (64, 69, and 67, respectively; p=NS). Prevalence of iron deficiency without anemia in 1981-1990, 1991-2000 and 2001-2010 was 7, 20 and 12%, respectively (p<0.05). Finally, prevalence of iron depleted stores was 20, 6 and 10%, respectively (p<0.05). Conclusions. Prevalence of iron deficiency anemia in Chilean women of childbearing age was mild between 1981 and 2010. More than 60% of childbearing age women presented normal iron status in all periods. However, prevalence of iron depleted stores was moderate during 1981-1990, and was mild during 1991-2000 and 2001-2010.

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