Benfotiamine supplementation prevents oxidative stress in anterior tibialis muscle and heart

2019 ◽  
Vol 17 (6) ◽  
pp. 423-429 ◽  
Author(s):  
Álisson de Carvalho Gonçalves ◽  
Einy Jéssika Siqueira Moreira ◽  
Guilherme Vannucchi Portari
2016 ◽  
Vol 30 (4) ◽  
pp. 552-556
Author(s):  
Guru Dutta Satyarthee ◽  
Luis Rafael Moscote-Salazar ◽  
Anil Kothiwala ◽  
A.K. Mahapatra

Abstract Wasting of muscle is usually a feature of lower motor neuron pathology, astonishingly parasagittal intracranial lesion affecting parietal lobe of cerebral hemisphere may be associated with Wasting of contralateral calf muscle. It can be associated with spastic foot drop. Foot drop is a common neurological state presenting with weakness involving anterior tibialis muscle causing inability of foot extension. Foot drop is commonly caused lower motor neuron disease pathology and a common cause includes L4-L5 radiculopathy or peroneal peripheral neuropathy. However, extremely rarely can be caused by intracranial pathology e.g. falcine meningioma and represents an important localization sign. Authors report an interesting case of calf muscle wasting caused by falcine meningioma, which may escape detection to remind rare but extremely important neurological localizing sign and ask for through and further neurological evaluation prior to concluding a final neurological diagnosis.


1993 ◽  
Vol 91 (1) ◽  
pp. 154-157 ◽  
Author(s):  
Luca Siliprandi ◽  
Ginetta Martini ◽  
Angelo Chiarelli ◽  
Franco Mazzoleni

1980 ◽  
Vol 239 (3) ◽  
pp. C58-C65 ◽  
Author(s):  
C. S. Hintz ◽  
C. V. Lowry ◽  
K. K. Kaiser ◽  
D. McKee ◽  
O. H. Lowry

Individual muscle fibers from the rat anterior tibialis and soleus muscles were each analyzed in duplicate for lactate dehydrogenase (LDH, EC 1.1.1.27), malate dehydrogenase (MDH, EC 1.1.1.37), 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35), fumarate hydrotase (EC 4.2.1.2), glycogen phosphorylase (EC 2.4.1.1), 6-phosphofructokinase (EC 2.7.1.11), pyruvate kinase (EC 2.7.1.40), fructose-bisphosphatase (EC 3.1.3.11), and creatine kinase (EC 2.7.3.2). A few fibers were also analyzed for adenylate kinase (EC 2.7.4.3). In general, there was a wide and almost continuous spectrum of coordinated enzyme activities. In the tibialis muscle, two fiber groups could be clearly distinguished on the basis of MDH activity. The high MDH group had on the average lower LDH activity, but there was a great deal of overlap in LDH between the two groups. Less overlap was observed for phosphorylase and fructose-bisphosphatase, both inversely related to MDH. Only one main group of fibers (presumably slow twitch) was found in the soleus muscle, although enzyme activities also covered a wide range. These soleus fibers were clearly distinguished from the high MDH tibialis group by much lower activities of LDH, pyruvate kinase, and fructose-bisphosphatase.


2001 ◽  
Vol 18 (Supplement 23) ◽  
pp. 95-96
Author(s):  
A. De Haes ◽  
M. C. Houwertjes ◽  
M. H. De Baets ◽  
J. B. Kuks ◽  
J. H. Proost ◽  
...  

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