High throughput routine determination of 17 tyrosine kinase inhibitors by LC–MS/MS

2018 ◽  
Vol 150 ◽  
pp. 112-120 ◽  
Author(s):  
Camille Merienne ◽  
Marine Rousset ◽  
Dominique Ducint ◽  
Nadège Castaing ◽  
Karine Titier ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
High Throughput ◽  
Kinase Inhibitors

Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening

2008 ◽  
Vol 18 (1) ◽  
pp. 285-288 ◽  
Author(s):  
Taikou Usui ◽  
Hyun Seung Ban ◽  
Junpei Kawada ◽  
Takatsugu Hirokawa ◽  
Hiroyuki Nakamura
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
High Throughput ◽  
In Silico ◽  
High Throughput Screening ◽  
Kinase Inhibitors

Development and clinical application of a LC-MS/MS method for simultaneous determination of various tyrosine kinase inhibitors in human plasma

2012 ◽  
Vol 413 (1-2) ◽  
pp. 143-149 ◽  
Author(s):  
Lutz Götze ◽  
Axel Hegele ◽  
Stephan Klaus Metzelder ◽  
Harald Renz ◽  
Wolfgang Andreas Nockher
Keyword(s):  
Tyrosine Kinase ◽  
Simultaneous Determination ◽  
Human Plasma ◽  
Tyrosine Kinase Inhibitors ◽  
Clinical Application ◽  
Kinase Inhibitors

High-throughput colorimetric detection of tyrosine kinase inhibitors based on the aggregation of gold nanoparticles

2008 ◽  
Vol 373 (1) ◽  
pp. 161-163 ◽  
Author(s):  
Jun Oishi ◽  
Xiaoming Han ◽  
Jeong-Hun Kang ◽  
Yoji Asami ◽  
Takeshi Mori ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
High Throughput ◽  
Kinase Inhibitors ◽  
Colorimetric Detection

Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data

2009 ◽  
Vol 44 (9) ◽  
pp. 3712-3717 ◽  
Author(s):  
Elena Dreassi ◽  
Alessandra Tania Zizzari ◽  
Federico Falchi ◽  
Silvia Schenone ◽  
Annalisa Santucci ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Biological Data

Simultaneous identification and determination of eleven tyrosine kinase inhibitors by supercritical fluid chromatography-mass spectrometry

2019 ◽  
Vol 11 (16) ◽  
pp. 2211-2222
Author(s):  
Shaomin Zhang ◽  
Wei Jin ◽  
Yongjian Yang
Keyword(s):  
Mass Spectrometry ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Supercritical Fluid ◽  
Supercritical Fluid Chromatography ◽  
Analytical Method ◽  
Kinase Inhibitors ◽  
Chromatography Mass Spectrometry ◽  
Simultaneous Identification

A rapid analytical method using supercritical fluid chromatography (SFC) coupled to mass spectrometry for the simultaneous identification and determination of eleven tyrosine kinase inhibitors (TKIs) was developed and validated.

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