scholarly journals High level programming abstractions for leveraging hierarchical memories with micro-core architectures

2020 ◽  
Vol 138 ◽  
pp. 128-138
Author(s):  
Maurice Jamieson ◽  
Nick Brown
Keyword(s):  
Programming Abstractions ◽  
High Level

scholarly journals High-Level Programming Abstractions for Distributed Graph Processing

2018 ◽  
Vol 30 (2) ◽  
pp. 305-324 ◽  
Author(s):  
Vasiliki Kalavri ◽  
Vladimir Vlassov ◽  
Seif Haridi
Keyword(s):  
Graph Processing ◽  
Programming Abstractions ◽  
High Level

Programming and Synthesis for Software-defined FPGA Acceleration: Status and Future Prospects

2021 ◽  
Vol 14 (4) ◽  
pp. 1-39
Author(s):  
Yi-Hsiang Lai ◽  
Ecenur Ustun ◽  
Shaojie Xiang ◽  
Zhenman Fang ◽  
Hongbo Rong ◽  
...  
Keyword(s):  
High Performance ◽  
High Energy ◽  
Grand Challenge ◽  
Future Prospects ◽  
Trade Offs ◽  
Programming Abstractions ◽  
Challenges And Opportunities ◽  
The Masses ◽  
High Level ◽  
Rich Spectrum

FPGA-based accelerators are increasingly popular across a broad range of applications, because they offer massive parallelism, high energy efficiency, and great flexibility for customizations. However, difficulties in programming and integrating FPGAs have hindered their widespread adoption. Since the mid 2000s, there has been extensive research and development toward making FPGAs accessible to software-inclined developers, besides hardware specialists. Many programming models and automated synthesis tools, such as high-level synthesis, have been proposed to tackle this grand challenge. In this survey, we describe the progression and future prospects of the ongoing journey in significantly improving the software programmability of FPGAs. We first provide a taxonomy of the essential techniques for building a high-performance FPGA accelerator, which requires customizations of the compute engines, memory hierarchy, and data representations. We then summarize a rich spectrum of work on programming abstractions and optimizing compilers that provide different trade-offs between performance and productivity. Finally, we highlight several additional challenges and opportunities that deserve extra attention by the community to bring FPGA-based computing to the masses.

scholarly journals Modular Visualization of Distributed Systems

2011 ◽  
Vol 14 (1) ◽  
Author(s):  
Gustavo Guevara ◽  
Travis Desell ◽  
Jason LaPorte ◽  
Carlos A. Varela
Keyword(s):  
Distributed Systems ◽  
Distributed System ◽  
Migration Patterns ◽  
Distributed Application ◽  
Programming Abstractions ◽  
Quantitative Metrics ◽  
Adaptive Middleware ◽  
Modular Layout ◽  
Effective Visualization ◽  
High Level

Effective visualization is critical to developing, analyzing, and optimizing distributed systems. We havedeveloped OverView, a tool for online/offline distributed systems visualization, that enables modular layout mechanisms, so that different distributed system high-level programming abstractions such as actors or processes can be visualized in intuitive ways. OverView uses by default a hierarchical concentric layout that distinguishes entities from containers allowing migration patterns triggered by adaptive middleware to be visualized. In this paper, we develop a force-directed layout strategy that connects entities according to their communication patterns in order to directly exhibit the application communication topologies. In force-directed visualization, entities`'  locations are encoded with different colors to illustrate load balancing. We compare these layouts using quantitative metrics including communication to entity ratio, applied on common distributed application topologies. We conclude that modular visualization is necessary to effectively visualize distributed systems since no one layout is best for all applications.

scholarly journals High-Level Programming of Stencil Computations on Multi-GPU Systems Using the SkelCL Library

2014 ◽  
Vol 24 (03) ◽  
pp. 1441005 ◽  
Author(s):  
Michel Steuwer ◽  
Michael Haidl ◽  
Stefan Breuer ◽  
Sergei Gorlatch
Keyword(s):  
Parallel Implementation ◽  
Competitive Performance ◽  
Data Types ◽  
Stencil Computations ◽  
Automatic Data ◽  
Parallel Patterns ◽  
Multiple Gpus ◽  
Massively Parallel Systems ◽  
Programming Abstractions ◽  
High Level

The implementation of stencil computations on modern, massively parallel systems with GPUs and other accelerators currently relies on manually-tuned coding using low-level approaches like OpenCL and CUDA. This makes development of stencil applications a complex, time-consuming, and error-prone task. We describe how stencil computations can be programmed in our SkelCL approach that combines high-level programming abstractions with competitive performance on multi-GPU systems. SkelCL extends the OpenCL standard by three high-level features: 1) pre-implemented parallel patterns (a.k.a. skeletons); 2) container data types for vectors and matrices; 3) automatic data (re)distribution mechanism. We introduce two new SkelCL skeletons which specifically target stencil computations – MapOverlap and Stencil – and we describe their use for particular application examples, discuss their efficient parallel implementation, and report experimental results on systems with multiple GPUs. Our evaluation of three real-world applications shows that stencil code written with SkelCL is considerably shorter and offers competitive performance to hand-tuned OpenCL code.

TiDA: High-Level Programming Abstractions for Data Locality Management

2016 ◽  
pp. 116-135 ◽  
Author(s):  
Didem Unat ◽  
Tan Nguyen ◽  
Weiqun Zhang ◽  
Muhammed Nufail Farooqi ◽  
Burak Bastem ◽  
...  
Keyword(s):  
Data Locality ◽  
Programming Abstractions ◽  
High Level

Transcription factor/DNA interactions visualized by electron spectroscopic imaging

1992 ◽  
Vol 50 (1) ◽  
pp. 450-451
Author(s):  
David P. Bazett-Jones ◽  
Mark L. Brown
Keyword(s):  
Transcription Factor ◽  
Dna Sequences ◽  
Transcription Initiation ◽  
Molecular Mechanisms ◽  
Phosphorus Content ◽  
Spectroscopic Imaging ◽  
Electron Spectroscopic Imaging ◽  
Dna Backbone ◽  
Two Parameters ◽  
High Level

A multisubunit RNA polymerase enzyme is ultimately responsible for transcription initiation and elongation of RNA, but recognition of the proper start site by the enzyme is regulated by general, temporal and gene-specific trans-factors interacting at promoter and enhancer DNA sequences. To understand the molecular mechanisms which precisely regulate the transcription initiation event, it is crucial to elucidate the structure of the transcription factor/DNA complexes involved. Electron spectroscopic imaging (ESI) provides the opportunity to visualize individual DNA molecules. Enhancement of DNA contrast with ESI is accomplished by imaging with electrons that have interacted with inner shell electrons of phosphorus in the DNA backbone. Phosphorus detection at this intermediately high level of resolution (≈lnm) permits selective imaging of the DNA, to determine whether the protein factors compact, bend or wrap the DNA. Simultaneously, mass analysis and phosphorus content can be measured quantitatively, using adjacent DNA or tobacco mosaic virus (TMV) as mass and phosphorus standards. These two parameters provide stoichiometric information relating the ratios of protein:DNA content.

Advances in Stem Instrumentation for Biology

1990 ◽  
Vol 48 (1) ◽  
pp. 362-363
Author(s):  
J. S. Wall
Keyword(s):  
Scanning Transmission Electron Microscope ◽  
Carbon Films ◽  
Specimen Preparation ◽  
Material Deposition ◽  
Active User ◽  
Percent Improvement ◽  
Scanning Transmission ◽  
The Moment ◽  
Film Substrate ◽  
High Level

The forte of the Scanning transmission Electron Microscope (STEM) is high resolution imaging with high contrast on thin specimens, as demonstrated by visualization of single heavy atoms. of equal importance for biology is the efficient utilization of all available signals, permitting low dose imaging of unstained single molecules such as DNA.Our work at Brookhaven has concentrated on: 1) design and construction of instruments optimized for a narrow range of biological applications and 2) use of such instruments in a very active user/collaborator program. Therefore our program is highly interactive with a strong emphasis on producing results which are interpretable with a high level of confidence.The major challenge we face at the moment is specimen preparation. The resolution of the STEM is better than 2.5 A, but measurements of resolution vs. dose level off at a resolution of 20 A at a dose of 10 el/A2 on a well-behaved biological specimen such as TMV (tobacco mosaic virus). To track down this problem we are examining all aspects of specimen preparation: purification of biological material, deposition on the thin film substrate, washing, fast freezing and freeze drying. As we attempt to improve our equipment/technique, we use image analysis of TMV internal controls included in all STEM samples as a monitor sensitive enough to detect even a few percent improvement. For delicate specimens, carbon films can be very harsh-leading to disruption of the sample. Therefore we are developing conducting polymer films as alternative substrates, as described elsewhere in these Proceedings. For specimen preparation studies, we have identified (from our user/collaborator program ) a variety of “canary” specimens, each uniquely sensitive to one particular aspect of sample preparation, so we can attempt to separate the variables involved.

A Questionnaire Survey of Current Rehabilitation Practices for Adults With Normal Hearing Sensitivity Who Experience Auditory Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 738-761
Author(s):  
Tess K. Koerner ◽  
Melissa A. Papesh ◽  
Frederick J. Gallun
Keyword(s):  
Hearing Aids ◽  
Questionnaire Survey ◽  
Patient Population ◽  
Clinical Care ◽  
Normal Hearing ◽  
Auditory Training ◽  
Training Methods ◽  
Hearing Sensitivity ◽  
Considerable Benefit ◽  
High Level

Purpose A questionnaire survey was conducted to collect information from clinical audiologists about rehabilitation options for adult patients who report significant auditory difficulties despite having normal or near-normal hearing sensitivity. This work aimed to provide more information about what audiologists are currently doing in the clinic to manage auditory difficulties in this patient population and their views on the efficacy of recommended rehabilitation methods. Method A questionnaire survey containing multiple-choice and open-ended questions was developed and disseminated online. Invitations to participate were delivered via e-mail listservs and through business cards provided at annual audiology conferences. All responses were anonymous at the time of data collection. Results Responses were collected from 209 participants. The majority of participants reported seeing at least one normal-hearing patient per month who reported significant communication difficulties. However, few respondents indicated that their location had specific protocols for the treatment of these patients. Counseling was reported as the most frequent rehabilitation method, but results revealed that audiologists across various work settings are also successfully starting to fit patients with mild-gain hearing aids. Responses indicated that patient compliance with computer-based auditory training methods was regarded as low, with patients generally preferring device-based rehabilitation options. Conclusions Results from this questionnaire survey strongly suggest that audiologists frequently see normal-hearing patients who report auditory difficulties, but that few clinicians are equipped with established protocols for diagnosis and management. While many feel that mild-gain hearing aids provide considerable benefit for these patients, very little research has been conducted to date to support the use of hearing aids or other rehabilitation options for this unique patient population. This study reveals the critical need for additional research to establish evidence-based practice guidelines that will empower clinicians to provide a high level of clinical care and effective rehabilitation strategies to these patients.

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