Group B Streptococcal Colonization in 160 Mother-Baby Pairs: A Prospective Cohort Study

Substantial evidence has supported that moxibustion stimulates a unique phenomenon of Deqi, heat-sensitive moxibustion sensation. This study consisted of a multicenter, prospective cohort study with two parallel arms (A: heat-sensitive moxibustion sensation group; B: nonheat-sensitive moxibustion sensation group). All forms of moxibustion were applied unilaterally on the right leg with a triangle shape of three acupuncture points simultaneously (bilateral Xi Yan (EX-LE5) and He Ding (EX-LE2)). After one month the primary outcome parameter GPCRND-KOA showed significant differences between groups: trial group 5.23 ± 2.65 (adjusted mean ± SE) 95% CI [4.44~6.01] versus control group 7.43 ± 2.80 [6.59~8.26],P=0.0001. Significant differences were manifested in total M-JOA score during the follow-up period (P=0.0006). Mean knee circumference indicated significant difference between the groups (P=0.03;P=0.007). Overall, this evidence suggested that the effectiveness of the Deqi sensation group might be more superior than the non-Deqi sensation one in the treatment of KOA. This study was aimed at providing scientific evidence on the Deqi sensation of moxibustion and at showing that heat-sensitive moxibustion sensation is essential to achieve the preferable treatment effects of KOA.

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Open Technique Versus Blind Technique in Placement of Primary Ports in Laparoscopic Procedures- A Prospective Cohort Study

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2021/30610.15398 ◽

2021 ◽

Author(s):

Vivek Pahuja ◽

Nisha Rani ◽

Hershdeep Singh ◽

Kuldip Singh ◽

Pankaj Dugg ◽

...

Keyword(s):

Cohort Study ◽

Prospective Cohort Study ◽

Peritoneal Cavity ◽

Prospective Cohort ◽

P Value ◽

Open Technique ◽

Significant Difference ◽

Group A ◽

Group B ◽

Primary Port

Introduction: Laparoscopic access has always been a challenge because it has been associated with severe complications and sometimes fatal also. Aim:Tocompareopentechniqueversusblindtechniqueinplacement of primary port in various laparoscopic procedures in terms of operative time, complications, ease of use and acceptability. Materials and Methods: This prospective cohort study was conducted at Government Medical College, Patiala, Punjab, India, between June 2014 to August 2016. The study included 100 patients, which were divided into two groups. Group A (n=50) received placement of primary port by open technique and Group B (n=50) received placement of primary port by blind technique. The time taken for access into peritoneal cavity and duration of surgery was noted. Multivariate analysis done using Chi-square test, p-value of less than 0.05 was considered significant. Results: Mean age of patients in group A and group B was 42.66±12.37 years and 43.06±14.67 years, respectively. Majority of patients were females in both groups (n=45 in group A and n=39 in group B). There was no significant difference in time taken for access into peritoneal cavity (p-value>0.05). The duration of hospital stay (in hours) of the patients was 36.96 in Group A and 34.42 in Group B which was not statistically significant. The incidence of intraoperative and postoperative complications was not significant. Most common complication port site infections 3 (6%) in Group A. Conclusion: There was no significant difference between the two techniques with respect to time taken for peritoneal access and complications. In expert hands, both methods are comparable.

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Early versus delayed surgical evacuation of spontaneous supratentorial intracerebral hematoma: A prospective cohort study

Surgical Neurology International ◽

10.25259/sni_103_2020 ◽

2020 ◽

Vol 11 ◽

pp. 145 ◽

Cited By ~ 1

Author(s):

Mostafa Raafat ◽

Omar Abdelaleem Ragab ◽

Osama Mohamed Abdelwahab ◽

Mohamed Mamdouh Salama ◽

Mohamed Ahmed Hafez

Keyword(s):

Cohort Study ◽

Clinical Outcome ◽

Hospital Stay ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Intracerebral Hematoma ◽

Time Interval ◽

Surgical Evacuation ◽

Group A ◽

Group B

Background: The optimum timing for surgical evacuation of spontaneous supratentorial intracerebral hematoma (ICH) is still controversial. The aim of this study was to compare the clinical outcome following early versus delayed surgical evacuation of spontaneous supratentorial ICH. Methods: This is a prospective cohort study including 70 patients with spontaneous supratentorial ICH ≥30 cc in volume and Glasgow Coma Scale 8–12. Patients were divided into two groups based on the time interval between ictus and surgery; Group A (evacuated within 8 h from ictus) and Group B (evacuated >8 h from ictus). Outcome was assessed at discharge and at 2 months postoperative using extended Glasgow Outcome Scale. Results: The early evacuation group (Group A) included 44 patients and the late evacuation group (Group B) included 26 patients. Favorable outcome was achieved in 20.5% of the patients in Group A and in 11.5% of the patients in Group B. Mortality rate was 18.2% in Group A and 26.9% in Group B. Three patients in Group A and one patient in Group B required reoperation. The mean hospital stay was 17.18 days and 14.54 days in Groups A and B, respectively. Conclusion: Early surgical evacuation of spontaneous supratentorial ICH in patients with good preoperative conscious level is associated with better clinical outcome, particularly in the early postoperative period. Early surgical evacuation has no significant impact on the rate of reoperation or the length of hospital stay.

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The Effect of Intrapartum Vancomycin on Vaginal Group B Streptococcus Colony Counts

American Journal of Perinatology ◽

10.1055/s-0038-1675622 ◽

2018 ◽

Vol 36 (06) ◽

pp. 555-560 ◽

Cited By ~ 1

Author(s):

Maureen Hamel ◽

Phinnara Has ◽

Ilina Datkhaeva ◽

Kimberly Delacy ◽

Dana Ciolfi ◽

...

Keyword(s):

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Temporal Relationship ◽

Group B Streptococcus ◽

Subsequent Time ◽

Group B ◽

Percent Decline ◽

Subsequent Time Point ◽

Time Point

Objective To define the temporal relationship between intrapartum intravenous vancomycin administration and vaginal group B streptococcus (GBS) colony counts. Study Design Prospective cohort study conducted from October 2014 to February 2017. Women with antenatal cultures demonstrating GBS colonization and a plan for vancomycin administration were eligible. Intrapartum vaginal cultures were collected prior to the first vancomycin infusion and every 2 hours up to five collections or delivery. Results were analyzed in two groups: participants with at least one positive intrapartum culture and those without any positive intrapartum cultures. Results A total of 63 women were enrolled. Among consented women, a total of 8 were excluded and 3 participants' cultures were never plated, thus leaving a total of 52 women for analysis. The degree of vaginal GBS colonization varied between subjects and was not normally distributed. Colony counts dropped rapidly from hour 0 to hour 2 (median: 6.0 × 108 vs. 1.0 × 108, p < 0.01). Standardizing hour 0 colony counts to 100%, the percent decline in colony counts from hour 0 to hour 2 was significant (p = 0.03), and at each subsequent time point fell further. Conclusion GBS vaginal colony counts fall rapidly after intrapartum vancomycin administration.

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