Tailored treatment of aneurysmal bone cyst of the scapula: en bloc resection for the body and extended curettage for the neck and acromion

2020 ◽  
Vol 29 (5) ◽  
pp. 961-967 ◽  
Author(s):  
Khodamorad Jamshidi ◽  
Milad Haji Agha Bozorgi ◽  
Mikaiel Hajializade ◽  
Abolfazl Bagherifard ◽  
Alireza Mirzaei
Cancers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 2362
Author(s):  
Nils Deventer ◽  
Martin Schulze ◽  
Georg Gosheger ◽  
Marieke de Vaal ◽  
Niklas Deventer

(1) Background: An aneurysmal bone cyst (ABC) is a benign, locally aggressive tumor. Different treatment modalities are described in the literature i.e., en bloc resection, intralesional curettage and percutaneous sclerotherapy. (2) Methods: This single-center study is a review of 74 patients with primary ABCs who underwent a surgical treatment or polidocanol instillation. Cyst volume measurements using MRI and conventional radiographs are compared. (3) Results: The mean pre-interventional MRI-based cyst volume was 44.07 cm3 and the mean radiographic volume was 27.27 cm3. The recurrence rate after intralesional curettage with the need for further treatment was 38.2% (13/34). The instillation of polidocanol showed a significant reduction of the initial cyst volume (p < 0.001) but a persistent disease occurred in 29/32 cases (90.6%). In 10 of these 29 cases (34.5%) further treatment was necessary. After en bloc resection (eight cases) a local recurrence occurred in two cases (25%), in one case with the need for further treatment. (4) Conclusions: MRI scans are superior to biplanar radiographs in the examination of ABCs. Sequential percutaneous instillations of polidocanol are equally effective in the therapy of primary ABCs compared to intralesional curettage. However, several instillations have to be expected. In a considerable number of cases, a conversion to intralesional curettage or en bloc resection may be necessary.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Matthew Harcus ◽  
Samantha Aldridge ◽  
Adesegun Abudu ◽  
Lee Jeys ◽  
Senthil Senniappan ◽  
...  

Surgery is the main treatment option for patients with aneurysmal bone cyst (ABC). We report our experience of using denosumab as an alternative treatment in a child with a multiply recurrent and unresectable tibial ABC. The efficacy and safety of denosumab in the paediatric population, and in the treatment of ABC, are still to be fully evaluated. We describe a 13-year-old boy with an extensive and aggressive ABC involving the proximal tibia, which had recurred following multiple previous surgeries. The patient had ongoing severe pain, was unable to weight-bear, and was at significant risk of pathological fracture. En bloc resection and embolization were not deemed viable, and a decision to use denosumab was made. He received 17 doses of subcutaneous denosumab (70 mg/m2) over a 27-month period, at increasing dose intervals. His symptoms significantly improved, and bony consolidation was observed within six months of treatment. He was able to walk without protection and fully weight-bear without any pain by 18 months. With an increase to a six-month dosing interval, the patient presented with a severe, symptomatic rebound hypercalcaemia requiring bisphosphonate therapy. This reoccurred on two further occasions. This case adds to the evidence that denosumab is effective in the treatment of ABC in paediatric patients, but there is a risk of rebound hypercalcaemia. Therefore, patient awareness and biochemical monitoring for rebound hypercalcaemia are essential.


2021 ◽  
Vol 7 (1) ◽  
pp. 25-26
Author(s):  
Sunder Goyal ◽  
◽  
Snigdha ◽  

Aneurysmal cyst of bone is a rare benign tumour that is slowing growing and expansile in nature. Generally, occurs in the long bones but can also involve the vertebrae. An aneurysmal bone cyst from the rib, especially in the middle age group, is extremely uncommon. Hereby, we report a 40-year-old woman with an aneurysmal bone cyst of the left 6th rib. She was treated with en bloc rib excision with the cyst. FNAC of lesion proved the diagnosis of the aneurysmal bone cyst. Curative treatment is en bloc resection of the affected rib, leaving no chance of recurrence.


2019 ◽  
Vol 44 (5) ◽  
pp. 425.e1-425.e5 ◽  
Author(s):  
Ezequiel Ernesto Zaidenberg ◽  
Efrain Farias Cisneros ◽  
Ryan Miller ◽  
Carlos Rodolfo Zaidenberg

Author(s):  
Javier Sánchez Sánchez ◽  
José Aguilar Maldonado ◽  
Karem Barreno Haro

Keratocyst is a benign odontogenic lesion with aggressive behavior, probably derived from the dental lamina. It is frequently located in the posterior part of the mandibular bone in the area of ​​the third molar, mandibular angle and can progress towards the ramus and the body, presenting a direct association with retained dental organs. There is a wide variety of techniques for the treatment of this lesion, such as decompression, marsupialization, enucleation, and en bloc resection, as well as the combination of these with adjuvant methods. The interest in this lesion stems from its high recurrence rate, which is estimated to be 20-30% in the general population, however, at present the use of conservative treatments such as marsupialization and decompression has been chosen. demonstrated greater effectiveness and less recurrence. This is why after treating the lesions it is important to give a long-term follow-up. The objective of the publication is to present the report of a clinical case of a 21-year-old male patient with a diagnosis of odontogenic keratocyst treated with a decompression technique for five months for subsequent surgical enucleation. It has been proven that decompression treatment followed by enucleation and accompanied by adjuvant methods is an adequate therapeutic management for keratocysts as it demonstrates its lower rate of recurrence and its noble behavior with neighboring vital structures. However, in all cases, regular monitoring should be carried out to prevent recurrence of the lesion.


Author(s):  
João Isidro Fracasso ◽  
Antônio Benincá Albuquerque ◽  
André Luca Boeira Rovani ◽  
Larissa Maroni ◽  
Guilherme Baroni De Macedo ◽  
...  

Neuroendocrine tumors (NETs) are epithelial neoplasms with predominant neuroendocrine differentiation that arise in most organs of the body. Neuroendocrine tumors of the thymus (tNET) and mediastinum are very uncommon. We report the case of a 49-year-old male patient with neuroendocrine tumor of the thymus, superiorly in the anterior mediastinum, asymptomatic of the respiratory tract presenting with epigastric pain, treated with the lesion's surgical resection en bloc associated with radiotherapy and chemotherapy.


Author(s):  
Andrea Ziegler ◽  
Eric Thorpe

AbstractGlomus tumors are mesenchymal tumors that arise from glomus bodies and most frequently occur in the distal extremities. These tumors can occur throughout the body and are typically benign. However, a very small fraction of glomus tumors displays aggressive features and are considered atypical or malignant. We report on our experience and management of the first case in the literature of a malignant glomus tumor in a child originating in the paraspinal region with involvement of the cervical spine. Malignant glomus tumors tend to be locally aggressive, and en bloc resection is difficult, especially when the tumors occur in the head and neck. Additional studies on disease progression and adjuvant treatment outcomes are necessary to determine the best treatment approach and long-term outcomes in patients with malignant glomus tumors.


Foot & Ankle ◽  
1981 ◽  
Vol 1 (4) ◽  
pp. 235-244 ◽  
Author(s):  
Martin M. Malawer ◽  
Raymond Vance

Two cases of giant cell tumor and aneurysmal bone cyst of the talus were analyzed with a review of eight cases from the literature. This anatomic setting represents a distinct clinical and roentgenographic entity with a less aggressive natural history than the more common sites. All lesions presented a characteristic radiographic involvement of the head and neck of the talus. Eight of ten lesions were treated by curettage, with or without bone grafting, and healed. Two underwent partial en bloc resection. None developed late fracture, recurrence, avascular necrosis, or metastases. We concluded that a giant cell tumor or aneurysmal bone cyst when located in the talus may be difficult to differentiate but tends to exhibit a less aggressive biological behavior and a more favorable prognosis than the more classical proximal lesion. Talectomy is not indicated in the primary treatment. Curettage with or without bone graft has a high success rate. Cryosurgery should be reserved for a recurrent lesion.


2021 ◽  
Vol 94 (2) ◽  
pp. 256-259
Author(s):  
Miana Pop ◽  
Dana Bartos ◽  
Ofelia Anton ◽  
Ioana Rusu ◽  
Lidia Ciobanu ◽  
...  

Desmoid tumors (DT) are rare non-metastatic neoplasms that occur through myofibroblast proliferation in musculoaponeurotic or fascial structures of the body, being commonly diagnosed in young women during pregnancy or in the post-partum period. We present the case of a 38-year-old woman, who recently gave birth, manifesting non-specific abdominal symptoms. Computed tomography indicated the presence of a solitary tumor arising from the intestinal wall or from the mesentery. Surgery confirmed the diagnosis, revealing a tumor that was localized at the level of the jejunal mesentery, having about 7 cm in diameter, in tight contact with the duodenum and the mesenteric vessels. ‘‘En bloc’’ resection of the tumor was performed, together with the involved enteral loops followed by end-to-end anastomosis of the jejunum. Histopathological examination of the surgical specimen sustained the diagnosis of desmoid tumor.


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