Odontogenic keratocyst: diagnostic characteristics and conservative surgical treatment

Author(s):  
Javier Sánchez Sánchez ◽  
José Aguilar Maldonado ◽  
Karem Barreno Haro

Keratocyst is a benign odontogenic lesion with aggressive behavior, probably derived from the dental lamina. It is frequently located in the posterior part of the mandibular bone in the area of ​​the third molar, mandibular angle and can progress towards the ramus and the body, presenting a direct association with retained dental organs. There is a wide variety of techniques for the treatment of this lesion, such as decompression, marsupialization, enucleation, and en bloc resection, as well as the combination of these with adjuvant methods. The interest in this lesion stems from its high recurrence rate, which is estimated to be 20-30% in the general population, however, at present the use of conservative treatments such as marsupialization and decompression has been chosen. demonstrated greater effectiveness and less recurrence. This is why after treating the lesions it is important to give a long-term follow-up. The objective of the publication is to present the report of a clinical case of a 21-year-old male patient with a diagnosis of odontogenic keratocyst treated with a decompression technique for five months for subsequent surgical enucleation. It has been proven that decompression treatment followed by enucleation and accompanied by adjuvant methods is an adequate therapeutic management for keratocysts as it demonstrates its lower rate of recurrence and its noble behavior with neighboring vital structures. However, in all cases, regular monitoring should be carried out to prevent recurrence of the lesion.

Author(s):  
João Isidro Fracasso ◽  
Antônio Benincá Albuquerque ◽  
André Luca Boeira Rovani ◽  
Larissa Maroni ◽  
Guilherme Baroni De Macedo ◽  
...  

Neuroendocrine tumors (NETs) are epithelial neoplasms with predominant neuroendocrine differentiation that arise in most organs of the body. Neuroendocrine tumors of the thymus (tNET) and mediastinum are very uncommon. We report the case of a 49-year-old male patient with neuroendocrine tumor of the thymus, superiorly in the anterior mediastinum, asymptomatic of the respiratory tract presenting with epigastric pain, treated with the lesion's surgical resection en bloc associated with radiotherapy and chemotherapy.


Author(s):  
Andrea Ziegler ◽  
Eric Thorpe

AbstractGlomus tumors are mesenchymal tumors that arise from glomus bodies and most frequently occur in the distal extremities. These tumors can occur throughout the body and are typically benign. However, a very small fraction of glomus tumors displays aggressive features and are considered atypical or malignant. We report on our experience and management of the first case in the literature of a malignant glomus tumor in a child originating in the paraspinal region with involvement of the cervical spine. Malignant glomus tumors tend to be locally aggressive, and en bloc resection is difficult, especially when the tumors occur in the head and neck. Additional studies on disease progression and adjuvant treatment outcomes are necessary to determine the best treatment approach and long-term outcomes in patients with malignant glomus tumors.


2021 ◽  
Vol 94 (2) ◽  
pp. 256-259
Author(s):  
Miana Pop ◽  
Dana Bartos ◽  
Ofelia Anton ◽  
Ioana Rusu ◽  
Lidia Ciobanu ◽  
...  

Desmoid tumors (DT) are rare non-metastatic neoplasms that occur through myofibroblast proliferation in musculoaponeurotic or fascial structures of the body, being commonly diagnosed in young women during pregnancy or in the post-partum period. We present the case of a 38-year-old woman, who recently gave birth, manifesting non-specific abdominal symptoms. Computed tomography indicated the presence of a solitary tumor arising from the intestinal wall or from the mesentery. Surgery confirmed the diagnosis, revealing a tumor that was localized at the level of the jejunal mesentery, having about 7 cm in diameter, in tight contact with the duodenum and the mesenteric vessels. ‘‘En bloc’’ resection of the tumor was performed, together with the involved enteral loops followed by end-to-end anastomosis of the jejunum. Histopathological examination of the surgical specimen sustained the diagnosis of desmoid tumor.


2015 ◽  
Vol 8 (2) ◽  
pp. 84-88
Author(s):  
Chandra Kant ◽  
Virendra Kumar Prajapati ◽  
Vishwambhar Singh ◽  
Krishna Murari Tiwari

ABSTRACT Odontogenic fibromyxoma, a myxoma with abundant collagen fibers, is a rare benign tumor of jaw which mostly affects posterior part of mandible. It is ectomesenchymal in origin and probably arises from connective tissue of dental follicle or papilla. Commonly occurs in 2nd or 3rd decade with slight female predilection. Radiological investigations, such as conventional radiography, computed tomography (CT) scan or magnetic resonance imaging (MRI) can be used to differentiate it from other odontogenic tumors like ameloblastoma. Management is surgical by enucleation and curettage or by en bloc resection and segmental maxillectomy. Follow-up of patient is must for at least 2 years to diagnose any recurrence. In this article, we present fibromyxoma of maxilla which is a very rare site for occurrence of fibromyxoma and this relatively rare condition has been discussed in light of recent information from literature with a case report. How to cite this article Kant C, Prajapati VK, Singh V, Tiwari KM. Odontogenic Fibromyxoma of Maxilla: A Rare Case Report. Clin Rhinol An Int J 2015;8(2):84-88.


2021 ◽  
Vol 12 (1) ◽  
pp. 47-51
Author(s):  
Kunal Sadanand Joshi ◽  
Sisir Bodepudi ◽  
Santhosh Kumar Ganapathi ◽  
Chandrasekar Murugesan ◽  
Jagan Balu ◽  
...  

Abstract Tumors of the body and tail of the pancreas are often more aggressive than tumors of the head and would have often undergone metastatic spread to other organs at the time of diagnosis. Most patients with carcinoma of the body and tail of the pancreas present at a late stage. Surgery is only indicated in those patients in whom there is no evidence of metastatic spread. Surgery is often not possible in cancers of the body and tail of the pancreas if the tumor invades celiac artery. Controversy exists regarding the margin status impact of microscopic resection margin involvement (R1) after pancreaticoduodenectomy (PD) for PDAC. There are reports indicating the rate of R1 resections increases significantly after PD if pathological examination is standardized. In this report, we present the case of a 56-year-old female who had undergone lateral pancreaticojejunostomy for chronic pancreatitis 8 years ago, but has now developed malignancy of the body and tail of the pancreas involving multiple organs. This patient underwent en bloc resection involving: 1. distal pancreatectomy with jejunal loop (lateral pancreaticojejunostomy) resection; 2. splenectomy; 3. left nephrectomy; 4. total gastrectomy; and 5. segmental colectomy with reconstruction by esophagojejunostomy, jejunojejunostomy, and colocolic anastomosis. The infrequent occurrence of tumor in the distal gland and advanced tumor stage at the time of diagnosis have both combined to produce therapeutic nihilism/dilemma in the minds of many surgeons. This report highlights the decision on how much to the push limits for multi-organ resection (en bloc resection with distal pancreatectomy, gastrectomy, splenectomy, colectomy, nephrectomy) with the intent of achieving R0 status in spite of the complexity of surgery in selected patients.


2020 ◽  
Vol 29 (5) ◽  
pp. 961-967 ◽  
Author(s):  
Khodamorad Jamshidi ◽  
Milad Haji Agha Bozorgi ◽  
Mikaiel Hajializade ◽  
Abolfazl Bagherifard ◽  
Alireza Mirzaei

2019 ◽  
Vol 12 (5) ◽  
pp. e228774
Author(s):  
Gabriel Mekel ◽  
Eli Balshan ◽  
Frank Traupman

Solitary fibrous tumours (SFTs) are rare tumours arising from mesenchymal tissues. Despite of their more frequent occurrence in the pleura, SFT can present anywhere in the body. Only a few cases have been described arising from the mesentery. Most tumours have a benign nature; however, up to 20% of them can spread, most commonly to liver, lung and bone. Surgical excision including all surrounding tissues remains the treatment of choice; however, there is no consensus regarding the need for adjuvant therapies. We present a 79-year-old man with abdominal pain who was found to have a SFT in the mesentery of the sigmoid colon, treated with en bloc resection. A multidisciplinary team including surgeons, medical and radiation oncologists is recommended in the care of these patients.


2015 ◽  
Vol 63 (3) ◽  
pp. 327-330
Author(s):  
Carlos Henrique de CARVALHO E SOUZA ◽  
Jessyca Leal Moura FÉ ◽  
Lucas Lopes Araújo SOUSA ◽  
Márcia Socorro Da Costa BORBA ◽  
Simone Sousa Lobão Veras BARROS ◽  
...  

Ameloblastoma is an aggressive, benign odontogenic tumor of epithelial origin. Approximately 1-3% of all tumors and cysts of the maxillary bones are ameloblastomas. They grow at a slow but persistent rate and are mainly located in the ramus of the mandible. They are occasionally associated with the presence of an impacted third molar. Ameloblastomas are characterized by aggressive infiltration of the surrounding tissue. There may be a high local recurrence rate when the tumor is not properly removed, due to remaining tumor cells. This article reports a case of a multicystic ameloblastoma that had been previously treated with conservative therapy which failed and resulted in recurrence eight years later. Clinical examination showed extensive bone resorption in the right hemi-mandible region. Incisional biopsy and histopathological examination was carried out to confirm the diagnosis. The proposed treatment was total en bloc resection involving the right hemi-mandible, and the region of central and lateral left incisors with a two-centimeter safety margin. Radical surgical protocol with wide margin of safety must be adopted in order to prevent the recurrence of these aggressive tumors.


2019 ◽  
Vol 13 (1) ◽  
pp. 95-101 ◽  
Author(s):  
Ryota Koyama ◽  
Yoshiaki Maeda ◽  
Nozomi Minagawa ◽  
Toshiki Shinohara ◽  
Tomonori Hamada

An 89-year-old man was diagnosed with late cutaneous metastasis in the right axilla 6 years after undergoing a surgery for gastric cancer with synchronous cutaneous metastasis in the same site. The patient became aware of small reddish nodules in the right axilla, and computed tomography imaging showed an irregular thickening of the right axillary skin. No other sign of recurrence was observed. By en-bloc resection, the nodules were diagnosed as late cutaneous metastasis from gastric cancer. The patient received no additional postoperative chemo- or radiotherapy and was only carefully observed. Cutaneous metastases from gastric cancer have a high recurrence rate even if total resection with no residual cancer is achieved. Therefore, meticulous follow-up, including routine visual inspection, is required for the early detection of late cutaneous metastases.


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