Sex Differences in Outcomes and Associated Risk Factors After Acute Ischemic Stroke in Elderly Patients: A Prospective Follow-up Study

2015 ◽  
Vol 24 (10) ◽  
pp. 2277-2284 ◽  
Author(s):  
Bin Li ◽  
Tao Wang ◽  
Yongzhong Lou ◽  
Xiaofei Guo ◽  
Hongfei Gu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sex Differences ◽  
Ischemic Stroke ◽  
Elderly Patients ◽  
Acute Ischemic Stroke ◽  
Follow Up Study ◽  
Associated Risk Factors

scholarly journals Prevalence of cerebral microbleeds and other cardiovascular risk factors in elderly patients with acute ischemic stroke

2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Abeer Abdelzaher Ibrahim ◽  
Yosra Abdelzaher Ibrahim ◽  
Eman A. Darwish ◽  
Nivan Hany Khater
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
White Matter ◽  
Elderly Patients ◽  
Acute Ischemic Stroke ◽  
Recurrent Stroke ◽  
White Matter Lesions ◽  
Cerebral Microbleeds ◽  
Amyloid Angiopathy ◽  
Associated Risk Factors

Abstract Background Cerebral microbleeds are small, round dark-signal foci in the T2*-weighted magnetic resonance imaging. They are encountered in cerebral amyloid angiopathy and hypertensive vasculopathy. Their prevalence is common in ischemic stroke and cerebral hemorrhage. The purpose of this study is to investigate the prevalence of CMBs and associated risk factors in the elderly patients with acute ischemic stroke. Results Cerebral microbleeds were significantly associated with the presence of hypertension (in the subgroup of recurrent stroke) and with hypercholesterolemia. There was a significant association between the number of the microbleeds and severity of white matter lesions as a higher number of microbleeds related to more severe white matter lesions. The microbleeds were more prevalent in the group of patients using antithrombotics. Conclusion Age, hypercholesterolemia, and the use of antithrombotics emerged as the most important associated risk factors for the presence of CMBs. On MRI, there was a significant association between the number of CMBs and severity of white matter lesions as a higher number of CMBs related to more severe white matter lesions.

Clinical analysis of first-ever acute ischemic stroke involving the territory of paramedian mesencephalic arteries

Open Medicine ◽  
2007 ◽  
Vol 2 (1) ◽  
pp. 37-46 ◽  
Author(s):  
Peterus Thajeb ◽  
Teguh Thajeb ◽  
Dao-Fu Dai
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Age Of Onset ◽  
Clinical Analysis ◽  
Clinical Triad ◽  
One Year ◽  
Associated Risk Factors ◽  
A Prospective Study ◽  
Bilateral Lesions

AbstractTo determine one-year clinical outcome of patients with first-ever acute ischemic stroke involving the territory of paramedian mesencephalic arteries (PMAS), we conducted a prospective study evaluating the cognitive functions of 28 patients with PMAS. Neuropsychological tests were performed during the first month of stroke onset and at the 12th month of follow-up. There were 12 women and 16 men. Mean age of onset for women and men was 70 years and 65 years, respectively. Progressing strokes occurred in 62% of patients and 96% developed a full-blown picture of the clinical triad of akinetic mutism, hypersomnolence, and bilateral blepharoptosis and ophthalmoparesis. Involuntary movements occurred in 6, and focal myoclonus in 4 patients. The top four associated risk factors were hypertension (68%), hyperlipidemia (57%), diabetes mellitus (46%), and atrial fibrillation (36%). Unilateral midbrain infarctions occurred in 12 patients and bilateral lesions in 16. Thalamic infarctions were unilateral in 10 and bilateral in 13 cases. Three of the 28 (11%) patients died of recurrent cerebral infarctions within 1 year of the onset of PMAS. The recurrent infarctions involved the basilar artery territory in two cases and the carotid system in another. One patient died of acute myocardial infarction. Of the 24 patients who had survived the stroke by 1 year, 20 (71%) developed dementia. We conclude that first-ever ischemic stroke with PMAS is not a benign syndrome. Most patients developed dementia by 1 year after the stroke.

scholarly journals Incidence of cardiovascular diseases and associated risk factors among subjects with type 2 diabetes – An 11-year follow up study

2014 ◽  
Vol 66 (1) ◽  
pp. 5-10 ◽  
Author(s):  
K. Umamahesh ◽  
A. Vigneswari ◽  
G. Surya Thejaswi ◽  
K. Satyavani ◽  
Vijay Viswanathan
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Cardiovascular Diseases ◽  
Follow Up Study ◽  
Associated Risk Factors

Thrombolysis in acute ischemic stroke is associated with lower long-term hospital bed day use: A nationwide propensity score-matched follow-up study

2016 ◽  
Vol 11 (8) ◽  
pp. 910-916 ◽  
Author(s):  
Thorkild Terkelsen ◽  
Marie Louise Schmitz ◽  
Claus Z Simonsen ◽  
Heidi H Hundborg ◽  
Hanne K Christensen ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Propensity Score ◽  
Acute Ischemic Stroke ◽  
Follow Up Study ◽  
Hospital Bed

scholarly journals Progression of vertebral fractures in long-term controlled acromegaly: a 9-year follow-up study

2020 ◽  
Vol 183 (4) ◽  
pp. 427-437 ◽  
Author(s):  
I C M Pelsma ◽  
N R Biermasz ◽  
A M Pereira ◽  
W R van Furth ◽  
N M Appelman-Dijkstra ◽  
...  
Keyword(s):  
Risk Factors ◽  
Growth Hormone ◽  
Vertebral Fracture ◽  
Follow Up Study ◽  
Total Incidence ◽  
Point Increase ◽  
Associated Risk Factors ◽  
Spine Radiographs

Objective: Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) excess results in both reversible and irreversible musculoskeletal damage, including increased vertebral fracture (VF) risk. The prevalence of VFs is approximately 60% in controlled acromegaly patients, and these VFs can progress in time. We aimed to identify the course of VFs in a cohort of acromegaly patients in long-term remission and their associated risk factors during prolonged follow-up. Methods: Thirty-one patients with acromegaly (49% female, median age 60 years (IQR 53–66)), who were in remission for ≥2 years, were included in this longitudinal, prospective, follow-up study. Spine radiographs of vertebrae Th4 to L4 were assessed for VFs using the Genant score, at baseline, after 2.6 years and 9.1 years. Progression was defined as either a new fracture or a ≥1-point increase in Genant score. Results: The prevalence of VF at baseline was 87% (27/31 patients). Progression of VFs was observed in eleven patients (35.5%) during the 9.1-year follow-up period, with a total incidence rate of 65.5 per 1000 person years (males 59.8 per 1000 person years vs females 71.6 per 1000 person years). Patients treated with surgery or radiotherapy had a higher risk of VF progression in this cohort (P = 0.030). Conclusions: In this cohort of long-term, well-controlled acromegalic patients, the prevalence and progression of VFs was high, showing that the deleterious effects of GH and IGF-1 excess on bone persist despite achievement of longstanding remission.

scholarly journals Risk Factors for Fall in Elderly Patients: Follow-Up Study after Hospital Discharge

2018 ◽  
Vol 08 (04) ◽  
pp. 220-231
Author(s):  
Pedro Caetano ◽  
João Freitas ◽  
Carla Brandão ◽  
Tiago Teófilo ◽  
Inês Campos ◽  
...  
Keyword(s):  
Risk Factors ◽  
Elderly Patients ◽  
Hospital Discharge ◽  
Follow Up Study

scholarly journals C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke

2019 ◽  
Vol 70 (6) ◽  
pp. 2290-2293 ◽  
Author(s):  
Maria Totan ◽  
Elisabeta Antonescu ◽  
Maria Gabriela Catana ◽  
Maria Mihaela Cernusca-Mitariu ◽  
Lavinia Duica ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Inflammatory Marker ◽  
Protein A ◽  
Motor Deficit ◽  
Motor Deficits ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Associated Risk Factors

C-reactive protein (CRP) is a non-specific inflammatory marker, correlated with the severity and prognosis of ischemic stroke. We performed a retrospective study in which were included 81 patients diagnosed with acute ischemic stroke admitted between January and July 2017 in the Department of Neurology, Sibiu Emergency Clinical Hospital. CRP values were classified on three levels (0 - 5 mg / L, 5 - 50 mg / l and] 50 mg / l). We examined the correlation between CRP levels according to the type of ischemic (lacunar / territorial) stroke, the degree of motor deficit (quantified by the mRC scale), the associated risk factors and the mortality rate. PCR values above 50 mg / L were found in patients with territorial stroke (15%). Moderate motor deficits predominate, with PCR values ranging from 5-50 mg / L. The most important risk factors found in the patients included in our study were hypertension and atherosclerosis. We made correlations between these risk factors and the PCR values. In most cases with these two risk factors were recorded a mean PCR value (5-50 mg / L).For atherosclerosis the results were statistically significant, p = 0.021. Most patients (56%) had CRP levels ranging from 5 to 50 mg / L. These values recorded highest death rates. PCR it is an important marker of inflammation and it is important to be determined in all patients with acute ischemic stroke, especially which is thought to be correlated with the prognosis of these patients.

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