scholarly journals Dyslipidemia Is a Major Factor in Stem Cell Damage Induced by Uncontrolled Long-Term Type 2 Diabetes and Obesity in the Rat, as Suggested by the Effects on Stem Cell Culture

2018 ◽  
Vol 15 (12) ◽  
pp. 1678-1697 ◽  
Author(s):  
Maryam Masouminia ◽  
Robert Gelfand ◽  
Istvan Kovanecz ◽  
Dolores Vernet ◽  
James Tsao ◽  
...  
Author(s):  
A. L. Cunningham ◽  
J. W. Stephens ◽  
D. A. Harris

AbstractObesity and type 2 diabetes mellitus (T2DM) are common, chronic metabolic disorders with associated significant long-term health problems at global epidemic levels. It is recognised that gut microbiota play a central role in maintaining host homeostasis and through technological advances in both animal and human models it is becoming clear that gut microbiota are heavily involved in key pathophysiological roles in the aetiology and progression of both conditions. This review will focus on current knowledge regarding microbiota interactions with short chain fatty acids, the host inflammatory response, signaling pathways, integrity of the intestinal barrier, the interaction of the gut-brain axis and the subsequent impact on the metabolic health of the host.


1998 ◽  
Vol 15 (12) ◽  
pp. 1022-1027 ◽  
Author(s):  
C. Weytjens ◽  
B. Keymeulen ◽  
C. Van Haleweyn ◽  
G. Somers ◽  
A. Bossuyt

2013 ◽  
Vol 60 (5) ◽  
pp. 249-253
Author(s):  
Irene Vinagre ◽  
Juan Sánchez-Hernández ◽  
José Luis Sánchez-Quesada ◽  
Miguel Ángel María ◽  
Alberto de Leiva ◽  
...  

2013 ◽  
Vol 27 (6) ◽  
pp. 609-617 ◽  
Author(s):  
Hanna Skärstrand ◽  
L.B. Dahlin ◽  
Å. Lernmark ◽  
F. Vaziri-Sani

Diabetes Care ◽  
2003 ◽  
Vol 26 (3) ◽  
pp. 625-630 ◽  
Author(s):  
L. J.C. van Loon ◽  
M. Kruijshoop ◽  
P. P.C.A. Menheere ◽  
A. J.M. Wagenmakers ◽  
W. H.M. Saris ◽  
...  

Diabetes ◽  
2008 ◽  
Vol 57 (6) ◽  
pp. 1664-1673 ◽  
Author(s):  
V. Brussee ◽  
G. Guo ◽  
Y. Dong ◽  
C. Cheng ◽  
J. A. Martinez ◽  
...  

Author(s):  
Dhanesh Kattipparambil Rajan ◽  
Jarmo Verho ◽  
Joose Kreutzer ◽  
Hannu Valimaki ◽  
Heimo Ihalainen ◽  
...  

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