Gender difference in blood cadmium concentration in the general population: Can it be explained by iron deficiency?

2014 ◽  
Vol 28 (3) ◽  
pp. 322-327 ◽  
Author(s):  
Suk Hwan Kim ◽  
Yangho Kim ◽  
Nam-Soo Kim ◽  
Byung-Kook Lee
Author(s):  
Jaeouk Ahn ◽  
Nam-Soo Kim ◽  
Byung-Kook Lee ◽  
Inbo Oh ◽  
Yangho Kim

We measured changes in atmospheric and blood levels of lead and cadmium in the South Korean general population during the past decade. Blood data of 16,873 adults were taken from the Korean National Health and Nutrition Examination Survey (KNHANES, 2008–2017). Atmospheric data were taken from 66 air quality monitoring sites in 16 different regions in South Korea. From 2008 to 2017, the geometric mean (GM) blood lead level decreased from 2.37 to 1.46 μg/dL (38.4% decrease), and the atmospheric lead concentration decreased by 61.0% in the overall population. During this time, the GM blood cadmium level decreased from 0.88 to 0.72 μg/L (18.2% decrease), and the atmospheric cadmium concentration decreased by 63.6%. Multiple linear regression analysis indicated that a half reduction in air lead was associated with a 0.09 μg/dL decrease in blood lead (95% CI: 0.03 to 0.15) in a subgroup of the metropolitan city population. However, a half reduction in air cadmium had no significant effect on blood cadmium. Multiple linear regression analyses indicated that the decrease in blood lead level over 10 years in Korea was related to the decrease in atmospheric lead concentration. However, the decrease in blood cadmium level during this time was not significantly associated with the decrease in atmospheric cadmium concentration. Our findings suggest that inhalation is a major source of lead exposure, but not of cadmium exposure. Ingestion of dietary cadmium presumably has a stronger impact on blood cadmium levels.


1994 ◽  
Vol 152 (2) ◽  
pp. 161-167 ◽  
Author(s):  
Jean-Louis Benedetti ◽  
Eric Dewailly ◽  
Fernand Turcotte ◽  
Michel Lefebvre

1985 ◽  
Vol 78 (10) ◽  
pp. 838-841
Author(s):  
Hasan I Atrah

Iron, transferrin and ferritin were measured in serum samples from 16 patients with primary hypogammaglobulinemia. Transferrin saturation was low in 12 patients (75%) and serum ferritin was low in 9 patients (56.25%). Both parameters were low, confirming the state of iron deficiency, in 6 patients (37.5%). These figures are highly significant ( P < 0.01) when compared with the prevalence of iron deficiency in the general population. Eight patients were maintained on intravenous immunoglobulin infusions and the rest on intramuscular immunoglobulin injections, their mean serum IgG being 4.4 g/l and 2.6 g/l respectively. There was no difference in the prevalence of iron deficiency between the two groups.


Epidemiology ◽  
2011 ◽  
Vol 22 ◽  
pp. S291
Author(s):  
Byoung-gwon Kim ◽  
Yu-mi Kim ◽  
Jung-man Kim ◽  
Seung-do Yu ◽  
Byung-kook Lee ◽  
...  

Author(s):  
Roberta J. Ward ◽  
Monica Fisher ◽  
Marisol Tellez-Yudilevich

Summary Cadmium concentrations in whole blood have been determined in normal control subjects, in patients with untreated essential hypertension or with treated essential hypertension, and in those with acute or chronic renal disorders. High cadmium concentrations were not found in the patients with untreated essential hypertension. Most tobacco smokers were found to have high blood cadmium concentrations. When the mean cadmium concentrations from each group of patients were compared with those of the control subjects no significant differences were found. When the four groups were divided into smokers and non-smokers, however, a significantly higher mean value was found for the non-smoking renal patients in comparison with the non-smoking normal subjects. The marked increases in blood cadmium concentration in the patients with renal disorders may be attributed to impaired excretion.


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