Selenium intake and status of postpartum women and postnatal depression during the first year after childbirth in New Zealand – Mother and Infant Nutrition Investigation (MINI) study

2020 ◽  
Vol 61 ◽  
pp. 126503
Author(s):  
Ying Jin ◽  
Jane Coad ◽  
Rachael Pond ◽  
Nick Kim ◽  
Louise Brough
10.2196/18560 ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. e18560
Author(s):  
Ying Jin ◽  
Jane Coad ◽  
Shao J Zhou ◽  
Sheila Skeaff ◽  
Cheryl Benn ◽  
...  

Background Thyroid dysfunction is associated with cognitive impairment, mood disturbance, and postnatal depression. Sufficient thyroid hormone synthesis requires adequate intake of iodine, selenium, and iron. Iodine deficiency was historically a problem for New Zealand, and initiatives were introduced to overcome the problem: (1) mandatory fortification of all bread (except organic) with iodized salt (2009) and (2) provision of subsidized iodine supplements for pregnant and breastfeeding women (2010). Subsequent to these initiatives, most adults and children have adequate iodine status; however, status among breastfeeding women and their infants remains unclear. This paper outlines the methodology of the Mother and Infant Nutrition Investigation (MINI) study: an observational longitudinal cohort study of breastfeeding women and their infants. Objective This study will determine (1) women’s iodine intake and status among supplement users and nonusers; (2) women’s intake and status of iodine, selenium, and iron relating to thyroid function; (3) associations between women’s selenium status, thyroid function, and postnatal depression; (4) infants’ iodine and selenium status relating to first year neurodevelopment. Methods Breastfeeding women aged over 16 years with a healthy term singleton infant were recruited from Manawatu, New Zealand. Participants attended study visits 3, 6, and 12 months postpartum. Maternal questionnaires investigated supplement use before and after birth, iodine knowledge, and demographic information. Dietary assessment and urine, blood, and breast milk samples were taken to measure iodine, selenium, and iron intake/status. The Edinburgh Postnatal Depression Scale was used repeatedly to screen for postnatal depression. Thyroid hormones (free triiodothyronine, free thyroxine, thyroid stimulating hormone, thyroglobulin, antithyroglobulin antibodies, and antithyroid peroxidase) were measured in blood samples, and thyroid gland volume was measured by ultrasound at 6 months postpartum. Infant iodine and selenium concentrations were determined in urine. The Ages and Stages Questionnaire was used to assess infant development at 4, 8, and 12 months. Results Data collection was completed. Biological samples analysis, excluding nail clippings, is complete. Data analysis and presentation of the results will be available after 2020. Conclusions This study will provide data on the current iodine status of breastfeeding women. It will also provide a greater understanding of the three essential minerals required for optimal thyroid function among breastfeeding women. The prospective longitudinal design allows opportunities to examine women’s mental health and infant neurodevelopment throughout the first year, a crucial time for both mothers and their infants. Trial Registration Australian New Zealand Clinical Trials Registry ACTRN12615001028594; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=369324 International Registered Report Identifier (IRRID) DERR1-10.2196/18560


2020 ◽  
Author(s):  
Ying Jin ◽  
Jane Coad ◽  
Shao J Zhou ◽  
Sheila Skeaff ◽  
Cheryl Benn ◽  
...  

BACKGROUND Thyroid dysfunction is associated with cognitive impairment, mood disturbance, and postnatal depression. Sufficient thyroid hormone synthesis requires adequate intake of iodine, selenium, and iron. Iodine deficiency was historically a problem for New Zealand, and initiatives were introduced to overcome the problem: (1) mandatory fortification of all bread (except organic) with iodized salt (2009) and (2) provision of subsidized iodine supplements for pregnant and breastfeeding women (2010). Subsequent to these initiatives, most adults and children have adequate iodine status; however, status among breastfeeding women and their infants remains unclear. This paper outlines the methodology of the Mother and Infant Nutrition Investigation (MINI) study: an observational longitudinal cohort study of breastfeeding women and their infants. OBJECTIVE This study will determine (1) women’s iodine intake and status among supplement users and nonusers; (2) women’s intake and status of iodine, selenium, and iron relating to thyroid function; (3) associations between women’s selenium status, thyroid function, and postnatal depression; (4) infants’ iodine and selenium status relating to first year neurodevelopment. METHODS Breastfeeding women aged over 16 years with a healthy term singleton infant were recruited from Manawatu, New Zealand. Participants attended study visits 3, 6, and 12 months postpartum. Maternal questionnaires investigated supplement use before and after birth, iodine knowledge, and demographic information. Dietary assessment and urine, blood, and breast milk samples were taken to measure iodine, selenium, and iron intake/status. The Edinburgh Postnatal Depression Scale was used repeatedly to screen for postnatal depression. Thyroid hormones (free triiodothyronine, free thyroxine, thyroid stimulating hormone, thyroglobulin, antithyroglobulin antibodies, and antithyroid peroxidase) were measured in blood samples, and thyroid gland volume was measured by ultrasound at 6 months postpartum. Infant iodine and selenium concentrations were determined in urine. The Ages and Stages Questionnaire was used to assess infant development at 4, 8, and 12 months. RESULTS Data collection was completed. Biological samples analysis, excluding nail clippings, is complete. Data analysis and presentation of the results will be available after 2020. CONCLUSIONS This study will provide data on the current iodine status of breastfeeding women. It will also provide a greater understanding of the three essential minerals required for optimal thyroid function among breastfeeding women. The prospective longitudinal design allows opportunities to examine women’s mental health and infant neurodevelopment throughout the first year, a crucial time for both mothers and their infants. CLINICALTRIAL Australian New Zealand Clinical Trials Registry ACTRN12615001028594; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=369324 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/18560


2021 ◽  
pp. 1-13
Author(s):  
Nele Hockamp ◽  
Constanze Burak ◽  
Erika Sievers ◽  
Silvia Rudloff ◽  
Anja Burmann ◽  
...  

Abstract Objectives: The present study aimed to assess the current state of breast-feeding promotion in hospitals and the prevalence of breast-feeding during the first year of life in Germany and to compare the results with a study 20 years earlier. Design: In the studies on ‘breast-feeding and infant nutrition in Germany’ named ‘SuSe’, a cross-sectional survey in hospitals was combined with a subsequent prospective survey of breast-feeding and infant nutrition during the first year of life (0·5, 2, 4, 6 and 12 months after birth) in mother–infant pairs who were recruited in the hospitals. Written questionnaires and phone calls were used in SuSe I and web-based questionnaires in SuSe II. Breast-feeding promotion and prevalence were evaluated using recommendations from the WHO and the UNICEF. Setting: Two nationwide surveys SuSe I (1997–1998) and SuSe II (2017–2019). Participants: In SuSe I, 177 hospitals and 1717 mother–infant pairs and in SuSe II 109 hospitals and 962 mother–infant pairs were included. Results: In SuSe II, hospitals implemented seven of the WHO ‘Ten Steps to Successful Breastfeeding’ to a greater extent than the hospitals in SuSe I. More mothers exclusively breastfed for 4 months (57 % v. 33 %) and continued breast-feeding until 6 (78 % v. 48 %) and 12 months (41 % v. 13 %). In both studies, exclusive breast-feeding decreased between 4 and 6 months of age due to the introduction of complementary feeding. Conclusions: In Germany, breast-feeding habits have come closer to the recommendations over the last 20 years.


2013 ◽  
Vol 95 (8) ◽  
pp. 274-275
Author(s):  
Wyn Beasley

Arthur Porritt, whose adventures, accolades and achievements spanned the globe, was both a surgeon himself and the son of a surgeon. His father, Ernest Edward Porritt, qualified in Edinburgh, became a fellow of the Royal College of Surgeons of Edinburgh in 1898, and practised in Wanganui in new zealand, where Arthur was born on 10 August 1900. His mother, Ivy McKenzie, died in 1914, when Arthur was in his first year at Wanganui Collegiate School; and when his father shortly went overseas to serve in the First World War, the boy became a boarder. The future Olympian distinguished himself as athletics champion, a member of the First XV and a prefect; and for a year after leaving school himself, he taught at a boys' school.


1984 ◽  
Vol 39 (1) ◽  
pp. 51-57 ◽  
Author(s):  
C. A. Morris

ABSTRACTThe calving dates of spring-calving cows in New Zealand Angus and Hereford herds, taken from 350 and 240 herd-years respectively, and the intercalving intervals (CI) of cows in 95 Angus and 73 Hereford herds have been summarized. The relationships of each CI with the calving date which initiated it were also analysed. Results for each breed were analysed taking account of district, herd, year and cow age (in years), a total of 35 890 Angus and 22 397 Hereford records being used. The first-calving date (FCD) was identified for each herd-year, and 0·82 of Angus and 0·75 of Hereford cows were recorded as calving within 60 days of the FCD. On a herd basis, proportionately only 0·27 of Angus and 0·15 of Hereford herds had calving spreads of 80 days or less (defined as the time from the FCD to the last calving date). With barren years ignored, the CIs of cows averaged 370 days (Angus) and 368 days (Hereford). Two-year-old cows had on average a CI of 12 (Angus) or 7 days (Hereford) longer in 1974-75 than older cows, and the differences were both 12 days in 1975-76. Regression analyses showed that, on average, the later the calving date within a herd-year and age group, the shorter the subsequent CI. For cows calving early in the first year, the CI increased by 7 days for Angus and 5·4 days for Herefords for each 10 days before the mean calving date for the breed. There were significant effects of district and cow age on the regression estimates. The overall regressions were not consistent with those derived from British beef industry data.


2016 ◽  
Vol 53 (3) ◽  
pp. 223-231 ◽  
Author(s):  
Mark R Hobbs ◽  
Susan MB Morton ◽  
Polly Atatoa-Carr ◽  
Stephen R Ritchie ◽  
Mark G Thomas ◽  
...  

1978 ◽  
Vol 39 (3) ◽  
pp. 579-587 ◽  
Author(s):  
Christine D. Thomson ◽  
Catherine E. Burton ◽  
Marion F. Robinson

1. Urinary and faecal excretion of single oral doses of 1 mg selenium or 0.1 mg Se as selenomethionine (Semet-Se) in solution were studied in two women. Most of the Se was absorbed and little was eliminated in the urine (0.05–0.22 dose).2. The results have been compared with those from an earlier study (Thomson, 1974) on the same two women after similarly sized doses of sodium selenite (selenite-Se) in solution. Although selenite-Se was almost as well absorbed as Semet-Se more was excreted in the urine (0.41–0.85 dose).3. Repeated dosing with 1 mg selenite-Se on five consecutive days in one of the women indicated that 1.1 mg had been retained.4. Twenty patients with muscular complaints from Tapanui (South Otago, New Zealand), a low-Se soil area, ingested 0.5 mg selenite-Se daily for 20 d. Blood Se increased rapidly to almost twice the initial concentration but reached a plateau well below most values reported for residents outside New Zealand. No difference in blood Se concentration was found between those who did or did not report improvement.5. Spasmodic medication with selenite-Se by some residents near Lincoln (Christchurch, New Zealand) for periods of up to 10 years or more had increased the blood Se somewhat.


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