scholarly journals Hepatoprotective effect of hydromethanolic leaf extract of Musanga cecropioides (Urticaceae) on carbon tetrachloride-induced liver injury and oxidative stress

2018 ◽  
Vol 13 (4) ◽  
pp. 344-354 ◽  
Author(s):  
Lucky L. Nwidu ◽  
Yibala I. Oboma ◽  
Ekramy Elmorsy ◽  
Wayne G. Carter
2018 ◽  
Vol 21 (9) ◽  
pp. 899-904 ◽  
Author(s):  
Derya Ustuner ◽  
Emine Colak ◽  
Murat Dincer ◽  
Neslihan Tekin ◽  
Dilek Burukoglu Donmez ◽  
...  

2008 ◽  
Vol 60 (6) ◽  
pp. 475-480 ◽  
Author(s):  
Güldal Mehmetçik ◽  
Gül Özdemirler ◽  
Necla Koçak-Toker ◽  
Uğur Çevikbaş ◽  
Müjdat Uysal

2019 ◽  
Vol 17 (4) ◽  
pp. 426-431
Author(s):  
Jin Xuezhu ◽  
Li Jitong ◽  
Nie Leigang ◽  
Xue Junlai

The main purpose of this study is to investigate the role of citrus leaf extract in carbon tetrachloride-induced hepatic injury and its potential molecular mechanism. Carbon tetrachloride was used to construct hepatic injury animal model. To this end, rats were randomly divided into 4 groups: control, carbon tetrachloride-treated, and two carbon tetrachloride + citrus leaf extract-treated groups. The results show that citrus leaf extract treatment significantly reversed the effects of carbon tetrachloride on the body weight changes and liver index. Besides, treatment with citrus leaf extract also reduced the levels of serum liver enzymes and oxidative stress in a dose-dependent manner. H&E staining and western blotting suggested that citrus leaf extract could repair liver histological damage by regulating AMPK and Nrf-2.


2016 ◽  
Vol 17 (12) ◽  
pp. 2056 ◽  
Author(s):  
Wen-Huang Peng ◽  
Yi-Wen Chen ◽  
Meng-Shiou Lee ◽  
Wen-Te Chang ◽  
Jen-Chieh Tsai ◽  
...  

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