1778 WHY PATIENTS STOP TAKING ANTICHOLINERGIC MEDICATIONS FOR OVERACTIVE BLADDER: CREATION AND RESULTS OF A VALIDATED QUESTIONNAIRE.

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Jocelyn Rieder ◽  
Stephanie Tovar ◽  
Elizabeth Johnston ◽  
Ali Zhumkhawala ◽  
Viet Tran ◽  
...  
2016 ◽  
Vol 10 (7-8) ◽  
pp. 277 ◽  
Author(s):  
Christopher J.D. Wallis ◽  
Colin Lundeen ◽  
Nicole Golda ◽  
Hilary Brotherhood ◽  
Peter Pommerville ◽  
...  

<p><strong>Introduction:</strong> We sought to understand the contemporary pharmacologic management of overactive bladder (OAB) in a single-payer system. We examined temporal trends in the use of anticholinergic<br />medications and assessed whether the likelihood of patients changing their anticholinergic therapy was predicted by their current therapy.</p><p><strong>Methods:</strong> We conducted a retrospective, population-based analysis of prescription records from the PharmaNet database in BC, Canada. We identified patients treated with one or more anticholinergic<br />prescriptions between 2001 and 2009. We characterized temporal trends in the use of anticholinergic medications. We used generalized estimating equations with a logit wing to assess the relationship between the type of anticholinergic medication and the change in prescription.</p><p><strong>Results:</strong> The 114 325 included patients filled 1 140 296 anticholinergic prescriptions. The number of prescriptions each year increased over the study, both in aggregate and for each individual medication. While oxybutynin was the most commonly prescribed medication (68% of all prescriptions), the proportion of newer anticholinergics (solifenacin, darifenacin, and trospium) prescribed increased over time (p&lt;0.0001). Patients taking tolterodine (odds ratio [OR] 1.03; p=0.01) and darifenacin (OR 1.12; p=0.0006) were significantly more likely to change their prescription than those taking oxybutynin. There was no association seen for patients taking solifenacin (p=0.6) and trospium (p=0.9).</p><p><strong>Conclusions:</strong> There are an increasing number of anticholinergic prescriptions being filled annually. Patients taking newer anticholinergics are at least as likely to change therapy as those taking<br />oxybutynin. The reimbursement environment in BC likely affects these results. Restrictions in the available data limit assessment of other relevant predictors.</p>


2019 ◽  
Vol 31 (12) ◽  
pp. 2653-2660 ◽  
Author(s):  
Shilpa Iyer ◽  
Svjetlana Lozo ◽  
Carolyn Botros ◽  
Chi Wang ◽  
Alexandra Warren ◽  
...  

2020 ◽  
Vol 5 (4) ◽  
pp. 959-970
Author(s):  
Kelly M. Reavis ◽  
James A. Henry ◽  
Lynn M. Marshall ◽  
Kathleen F. Carlson

Purpose The aim of this study was to examine the relationship between tinnitus and self-reported mental health distress, namely, depression symptoms and perceived anxiety, in adults who participated in the National Health and Nutrition Examinations Survey between 2009 and 2012. A secondary aim was to determine if a history of serving in the military modified the associations between tinnitus and mental health distress. Method This was a cross-sectional study design of a national data set that included 5,550 U.S. community-dwelling adults ages 20 years and older, 12.7% of whom were military Veterans. Bivariable and multivariable logistic regression was used to estimate the association between tinnitus and mental health distress. All measures were based on self-report. Tinnitus and perceived anxiety were each assessed using a single question. Depression symptoms were assessed using the Patient Health Questionnaire, a validated questionnaire. Multivariable regression models were adjusted for key demographic and health factors, including self-reported hearing ability. Results Prevalence of tinnitus was 15%. Compared to adults without tinnitus, adults with tinnitus had a 1.8-fold increase in depression symptoms and a 1.5-fold increase in perceived anxiety after adjusting for potential confounders. Military Veteran status did not modify these observed associations. Conclusions Findings revealed an association between tinnitus and both depression symptoms and perceived anxiety, independent of potential confounders, among both Veterans and non-Veterans. These results suggest, on a population level, that individuals with tinnitus have a greater burden of perceived mental health distress and may benefit from interdisciplinary health care, self-help, and community-based interventions. Supplemental Material https://doi.org/10.23641/asha.12568475


Sign in / Sign up

Export Citation Format

Share Document