scholarly journals Construct Validity of SF-6D Health State Utility Values in an Employed Population

2014 ◽  
Vol 17 (7) ◽  
pp. A730-A731
Author(s):  
S. Baxter ◽  
K. Sanderson ◽  
A. Venn ◽  
P. Otahal ◽  
A.J. Palmer
2014 ◽  
Vol 24 (4) ◽  
pp. 851-870 ◽  
Author(s):  
Siyan Baxter ◽  
Kristy Sanderson ◽  
Alison Venn ◽  
Petr Otahal ◽  
Andrew J. Palmer

Author(s):  
Ryan O’Reilly ◽  
Sayako Yokoyama ◽  
Justin Boyle ◽  
Jeffrey C. Kwong ◽  
Allison McGeer ◽  
...  

2016 ◽  
Vol 23 (8) ◽  
pp. 1157-1166 ◽  
Author(s):  
Hasnat Ahmad ◽  
Bruce V Taylor ◽  
Ingrid van der Mei ◽  
Sam Colman ◽  
Beth A O’Leary ◽  
...  

Background: The measurement of health state utility values (HSUVs) for a representative sample of Australian people with multiple sclerosis (MS) has not previously been performed. Objectives: Our main aim was to quantify the HSUVs for different levels of disease severities in Australian people with MS. Method: HSUVs were calculated by employing a ‘judgement-based’ method that essentially creates EQ-5D-3L profiles based on WHOQOL-100 responses and then applying utility weights to each level in each dimension. A stepwise linear regression was used to evaluate the relationship between HSUVs and disease severity, classified as mild (Expanded Disability Status Scale (EDSS) levels: 0–3.5), moderate (EDSS levels: 4–6) and severe (EDSS levels: 6.5–9.5). Results: Mean HSUV for all people with MS was 0.53 (95% confidence interval (CI): 0.52–0.54). Utility decreased with increasing disease severity: 0.61 (95% CI: 0.60–0.62), 0.51 (95% CI: 0.50–0.52) and 0.40 (95% CI: 0.38–0.43) for mild, moderate and severe disease, respectively. Adjusted differences in mean HSUV between the three severity groups were statistically significant. Conclusion: For the first time in Australia, we have quantified the impact of increasing severity of MS on health utility of people with MS. The HSUVs we have generated will be useful in further health economic analyses of interventions that slow progression of MS.


2010 ◽  
Vol 10 (5) ◽  
pp. 553-566 ◽  
Author(s):  
Tessa Peasgood ◽  
Sue E Ward ◽  
John Brazier

2016 ◽  
Vol 19 (7) ◽  
pp. A875
Author(s):  
H Ahmad ◽  
I van der Mei ◽  
B Taylor ◽  
AJ Palmer

BMJ Open ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. e019978
Author(s):  
Lucy Kanya ◽  
Nana Anokye ◽  
Jennifer M Ryan

IntroductionIncreasingly, assessment of healthcare technologies and interventions requires the assessment of both costs and utilities. Health state utility values (HSUVs) are measured using a range of generic and condition-specific measures. While reviews have identified that generic measures of HSUVs may lack validity in adults with conditions that result in physical disability, there is little information available on the methods used to obtain HSUVs in children and adolescents with disabilities. The objectives of this systematic review are to describe the methods used to obtain HSUVs, including mode of administration and psychometric properties, and provide summary statistics for HSUVs among children and adolescents with disabilities.Methods and analysisThe following databases will be searched from inception for English-language studies of any design: PubMed, PsychInfo, Medline, Scopus, CINAHL Plus, Econlit and EMBASE databases. Two reviewers will independently screen titles, abstracts and full text articles for studies reporting HSUVs and/or data on the psychometric properties of preference-based measures for children and adolescents with disabilities aged up to 19 years. Two reviewers will independently extract data items including descriptors of the study methods and sample, instruments used to capture HSUVs, summary statistics for HSUVs and items relating to the quality of reporting. A descriptive summary of results from included studies and summary statistics for HSUVs will be presented. If sufficient data is identified, we will pool summary statistics for HSUVs according to the method used to obtain the HSUV using a random effects model. In addition, we will explore the determinants of the HSUVs using a meta-regression.Ethics and disseminationEthical approval will not be required as no original data will be collected as part of this review. The completed review will be submitted for publication in a peer-reviewed journal and presentation at conferences.PROSPERO registration numberCRD42018086574.


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