Comparison of Alternative Methods to Assess the Cost-Effectiveness of Tumor-Agnostic Therapies: A Triangulation Approach Using Larotrectinib as a Case Study

2021 ◽  
Author(s):  
Andrew Briggs ◽  
Beth Wehler ◽  
Jennifer G. Gaultney ◽  
Alex Upton ◽  
Antoine Italiano ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Alternative Methods ◽  
The Cost

Evaluating the cost-effectiveness of invasive alien plant clearing: A case study from South Africa

2012 ◽  
Vol 155 ◽  
pp. 128-135 ◽  
Author(s):  
Matthew M. McConnachie ◽  
Richard M. Cowling ◽  
Brian W. van Wilgen ◽  
Dominic A. McConnachie
Keyword(s):  
South Africa ◽  
Cost Effectiveness ◽  
Alien Plant ◽  
Invasive Alien Plant ◽  
The Cost

scholarly journals Comparing the cost effectiveness of nature-based and coastal adaptation: A case study from the Gulf Coast of the United States

PLoS ONE ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. e0192132 ◽  
Author(s):  
Borja G. Reguero ◽  
Michael W. Beck ◽  
David N. Bresch ◽  
Juliano Calil ◽  
Imen Meliane
Keyword(s):  
United States ◽  
Cost Effectiveness ◽  
Gulf Coast ◽  
The United States ◽  
Coastal Adaptation ◽  
The Cost

scholarly journals Modeling the Economic Impact of Interventions for Older Populations with Multimorbidity: A Method of Linking Multiple Single-Disease Models

2019 ◽  
Vol 39 (7) ◽  
pp. 842-856
Author(s):  
Ji-Hee Youn ◽  
Matt D. Stevenson ◽  
Praveen Thokala ◽  
Katherine Payne ◽  
Maria Goddard
Keyword(s):  
Health Care ◽  
Cost Effectiveness ◽  
Disease Models ◽  
Decision Analytic Model ◽  
Analytic Model ◽  
The Cost ◽  
Older Populations ◽  
Linked Model ◽  
Multiple Conditions

Introduction. Individuals from older populations tend to have more than 1 health condition (multimorbidity). Current approaches to produce economic evidence for clinical guidelines using decision-analytic models typically use a single-disease approach, which may not appropriately reflect the competing risks within a population with multimorbidity. This study aims to demonstrate a proof-of-concept method of modeling multiple conditions in a single decision-analytic model to estimate the impact of multimorbidity on the cost-effectiveness of interventions. Methods. Multiple conditions were modeled within a single decision-analytic model by linking multiple single-disease models. Individual discrete event simulation models were developed to evaluate the cost-effectiveness of preventative interventions for a case study assuming a UK National Health Service perspective. The case study used 3 diseases (heart disease, Alzheimer’s disease, and osteoporosis) that were combined within a single linked model. The linked model, with and without correlations between diseases incorporated, simulated the general population aged 45 years and older to compare results in terms of lifetime costs and quality-adjusted life-years (QALYs). Results. The estimated incremental costs and QALYs for health care interventions differed when 3 diseases were modeled simultaneously (£840; 0.234 QALYs) compared with aggregated results from 3 single-disease models (£408; 0.280QALYs). With correlations between diseases additionally incorporated, both absolute and incremental costs and QALY estimates changed in different directions, suggesting that the inclusion of correlations can alter model results. Discussion. Linking multiple single-disease models provides a methodological option for decision analysts who undertake research on populations with multimorbidity. It also has potential for wider applications in informing decisions on commissioning of health care services and long-term priority setting across diseases and health care programs through providing potentially more accurate estimations of the relative cost-effectiveness of interventions.

The Need for, and Benefits of, Documenting Human Factors Efforts

1980 ◽  
Vol 24 (1) ◽  
pp. 421-424
Author(s):  
Kenneth R. Stern
Keyword(s):  
Cost Effectiveness ◽  
Human Factors ◽  
Alternative Methods ◽  
The Cost

This presentation describes the need for, and benefits of, documenting savings realized through the application of human factors principles. Benefits of documenting savings are described as they affect the human factors specialist, management, and the customer. Non-recurring costs which result from a human factors investment, as well as resultant savings, must be considered in determining the cost-effectiveness of the intervention. Areas in which the human factors specialist can have an impact are defined and alternative methods of reporting savings are described.

Corrigendum to “Evaluating the cost-effectiveness of invasive alien plant clearing: a case study from South Africa” [Biol. Conserv. 155 (2012) 128–135]

2012 ◽  
Vol 156 ◽  
pp. 148
Author(s):  
Matthew M. McConnachie ◽  
Richard M. Cowling ◽  
Brian W. van Wilgen ◽  
Dominic A. McConnachie
Keyword(s):  
South Africa ◽  
Cost Effectiveness ◽  
Alien Plant ◽  
Invasive Alien Plant ◽  
The Cost
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