Anti-inflammatory and Antioxidant Effects of Japanese Herbal Medicine Kyoseihatekigan on Vocal Fold Wound Healing

2021 ◽  
Author(s):  
Satomi Ozawa ◽  
Shigeyuki Mukudai ◽  
Mami Kaneko ◽  
Shota Kinoshita ◽  
Keiko Hashimoto ◽  
...  
Keyword(s):  
Wound Healing ◽  
Herbal Medicine ◽  
Vocal Fold ◽  
Japanese Herbal Medicine ◽  
Anti Inflammatory ◽  
Antioxidant Effects

Anti-inflammatory effect of hospital-grade hochuekkito extract, a traditional Japanese herbal medicine, on methotrexate-induced intestinal mucositis in mice

2015 ◽  
Vol 2 (2) ◽  
pp. 81-88 ◽  
Author(s):  
Michiko Sekiya ◽  
Hiroaki Kiyohara ◽  
Hiroko Maruyama ◽  
Naoya Tsukada ◽  
Ayano Yasuda ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Japanese Herbal Medicine ◽  
Intestinal Mucositis ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update

2021 ◽  
Vol 12 ◽  
Author(s):  
Yiping Lin ◽  
Yuke Li ◽  
Yuanlian Zeng ◽  
Bin Tian ◽  
Xiaolan Qu ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Antitumor Activity ◽  
Molecular Mechanisms ◽  
Antibacterial Activities ◽  
Active Components ◽  
Pharmacological Activities ◽  
Wide Range ◽  
Japanese Herbal Medicine ◽  
Pharmacological Data ◽  
Anti Inflammatory

Magnolol (MG) is one of the primary active components of Magnoliae officinalis cortex, which has been widely used in traditional Chinese and Japanese herbal medicine and possesses a wide range of pharmacological activities. In recent years, attention has been drawn to this component due to its potential as an anti-inflammatory and antitumor drug. To summarize the new biological and pharmacological data on MG, we screened the literature from January 2011 to October 2020. In this review, we provide an actualization of already known anti-inflammatory, cardiovascular protection, antiangiogenesis, antidiabetes, hypoglycemic, antioxidation, neuroprotection, gastrointestinal protection, and antibacterial activities of MG. Besides, results from studies on antitumor activity are presented. We also summarized the molecular mechanisms, toxicity, bioavailability, and formulations of MG. Therefore, we provide a valid cognition of MG.

An in vitro model for investigation of vitamin A effects on wound healing

2021 ◽  
pp. 1-6
Author(s):  
Hoda Keshmiri Neghab ◽  
Mohammad Hasan Soheilifar ◽  
Gholamreza Esmaeeli Djavid
Keyword(s):  
Wound Healing ◽  
Endothelial Cell ◽  
Vitamin A ◽  
In Vitro Model ◽  
Cellular Proliferation ◽  
Endothelial Cell Migration ◽  
Normal Fibroblast ◽  
Anti Inflammatory ◽  
Vitro Model

Abstract. Wound healing consists of a series of highly orderly overlapping processes characterized by hemostasis, inflammation, proliferation, and remodeling. Prolongation or interruption in each phase can lead to delayed wound healing or a non-healing chronic wound. Vitamin A is a crucial nutrient that is most beneficial for the health of the skin. The present study was undertaken to determine the effect of vitamin A on regeneration, angiogenesis, and inflammation characteristics in an in vitro model system during wound healing. For this purpose, mouse skin normal fibroblast (L929), human umbilical vein endothelial cell (HUVEC), and monocyte/macrophage-like cell line (RAW 264.7) were considered to evaluate proliferation, angiogenesis, and anti-inflammatory responses, respectively. Vitamin A (0.1–5 μM) increased cellular proliferation of L929 and HUVEC (p < 0.05). Similarly, it stimulated angiogenesis by promoting endothelial cell migration up to approximately 4 fold and interestingly tube formation up to 8.5 fold (p < 0.01). Furthermore, vitamin A treatment was shown to decrease the level of nitric oxide production in a dose-dependent effect (p < 0.05), exhibiting the anti-inflammatory property of vitamin A in accelerating wound healing. These results may reveal the therapeutic potential of vitamin A in diabetic wound healing by stimulating regeneration, angiogenesis, and anti-inflammation responses.

In vitro anti-inflammatory and wound healing activities of Citrus auraptene

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
F Epifano ◽  
S Genovese ◽  
L Zhao ◽  
V Dang La ◽  
D Grenier
Keyword(s):  
Wound Healing ◽  
Anti Inflammatory
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