Carotid Endarterectomy remains cost-effective for the surgical management of carotid stenosis

Author(s):  
Natalie D. Sridharan ◽  
Rabih A. Chaer ◽  
Kennith Smith ◽  
Mohammad H. Eslami
2021 ◽  
Vol 233 (5) ◽  
pp. e234
Author(s):  
Natalie S. Domenick ◽  
Rabih S. Chaer ◽  
Kenneth Smith ◽  
Mohammad H. Eslami

1998 ◽  
Vol 3 (1) ◽  
pp. 6-11 ◽  
Author(s):  
Michael Lavender ◽  
Neil Craig ◽  
Ron Kerr ◽  
Denise Howel

Objectives: To investigate the benefit of carotid endarterectomy relative to medical treatment, by comparing the outcome for different groups of patients following transient ischaemic attacks. Methods: A Markov model was used to describe the survival and quality of life of patients treated for a transient ischaemic attack. The benefit is measured in terms of quality adjusted life months (QALMs). The outcome was estimated using a computer simulation with parameters based on published studies on the probability of events following treatment. The benefit of carotid endarterectomy was explored using a baseline set of parameters and a sensitivity analysis. Results: The baseline scenario of a 65-year-old male patient with the model factors set at an intermediate level showed a benefit for surgery of 3 QALMs compared with medical treatment alone. The sensitivity analysis showed that the most favourable combination of factors had a benefit of 13.4 QALMs and the least favourable a loss of 2 QALMs. Of all 128 factor combinations, 79.9% showed a benefit for surgery, 5.5% showed equal benefit, and 15.6% showed a benefit for medical treatment. Conclusions: Computer simulations have the potential for deriving estimates of benefit for different patient groups from the results of clinical trials. Combined with reliable information on costs, the technique could also demonstrate variations in cost-effectiveness for these groups. For patients following a transient ischaemic attack, the results from this simulation and limited cost information suggest that carotid endarterectomy is unlikely to be a cost-effective intervention in the UK for many patient groups despite a reduction in the risk of stroke.


1994 ◽  
Vol 41 (6) ◽  
pp. 443-449 ◽  
Author(s):  
Richard B. Libman ◽  
Ralph L. Sacco ◽  
Tianying Shi ◽  
James W. Correll ◽  
J.P. Mohr

2011 ◽  
Vol 165 (2) ◽  
pp. 180
Author(s):  
J.S. Whitehouse ◽  
T.T. Sato ◽  
J.C. Roberts ◽  
D.M. Gourlay ◽  
K.J. Brasel

2003 ◽  
Vol 17 (2-3) ◽  
pp. 123-127 ◽  
Author(s):  
Kazumi Kimura ◽  
Jacinda L. Stork ◽  
Christopher R. Levi ◽  
Anne L. Abbott ◽  
Geoffrey A. Donnan ◽  
...  

Neurosurgery ◽  
2014 ◽  
Vol 74 (suppl_1) ◽  
pp. S92-S101 ◽  
Author(s):  
Jorge L. Eller ◽  
Travis M. Dumont ◽  
Grant C. Sorkin ◽  
Maxim Mokin ◽  
Elad I. Levy ◽  
...  

Abstract Carotid artery stenting has become a viable alternative to carotid endarterectomy in the management of carotid stenosis. Over the past 20 years, many trials have attempted to compare both treatment modalities and establish the indications for each one, depending on clinical and anatomic features presented by patients. Concurrently, carotid stenting techniques and devices have evolved and made endovascular management of carotid stenosis safe and effective. Among the most important innovations are devices for distal and proximal embolic protection and new stent designs. This paper reviews these advances in the endovascular management of carotid artery stenosis within the context of the historical background.


1992 ◽  
Vol 16 (3) ◽  
pp. 354-362 ◽  
Author(s):  
Gerald S. Treiman ◽  
Judith M. Jenkins ◽  
William H. Edwards ◽  
William Barlow ◽  
William H. Edwards ◽  
...  

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