scholarly journals Mobilizing the social infrastructure of informal settlements in infectious disease response – The case of Ebola Virus Disease in West Africa

2022 ◽  
Vol 217 ◽  
pp. 104256
Author(s):  
S. Harris Ali ◽  
Mosoka P. Fallah ◽  
Joseph Mustapha McCarthy ◽  
Roger Keil ◽  
Creighton Connolly
Keyword(s):  
Infectious Disease ◽  
West Africa ◽  
Ebola Virus ◽  
Virus Disease ◽  
Informal Settlements ◽  
Ebola Virus Disease ◽  
Social Infrastructure ◽  
Disease Response ◽  
The Social

Priorities for Ebola virus disease response in west Africa

The Lancet ◽  
2014 ◽  
Vol 384 (9957) ◽  
pp. 1843 ◽  
Author(s):  
Shevin T Jacob ◽  
Ian Crozier ◽  
John S Schieffelin ◽  
Robert Colebunders
Keyword(s):  
West Africa ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
Disease Response

scholarly journals Ebola virus disease: a highly fatal infectious disease reemerging in West Africa

2015 ◽  
Vol 17 (2) ◽  
pp. 84-97 ◽  
Author(s):  
Kelvin K.W. To ◽  
Jasper F.W. Chan ◽  
Alan K.L. Tsang ◽  
Vincent C.C. Cheng ◽  
Kwok-Yung Yuen
Keyword(s):  
Infectious Disease ◽  
West Africa ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease

scholarly journals Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
T. R. W. Tipton ◽  
Y. Hall ◽  
J. A. Bore ◽  
A. White ◽  
L. S. Sibley ◽  
...  
Keyword(s):  
T Cell ◽  
West Africa ◽  
Cell Response ◽  
Ebola Virus ◽  
Medical Condition ◽  
Virus Disease ◽  
T Cell Response ◽  
Ebola Virus Disease ◽  
Cell Phenotype ◽  
T Cell Epitopes

AbstractZaireebolavirus (EBOV) is a highly pathogenic filovirus which can result in Ebola virus disease (EVD); a serious medical condition that presents as flu like symptoms but then often leads to more serious or fatal outcomes. The 2013–16 West Africa epidemic saw an unparalleled number of cases. Here we show characterisation and identification of T cell epitopes in surviving patients from Guinea to the EBOV glycoprotein. We perform interferon gamma (IFNγ) ELISpot using a glycoprotein peptide library to identify T cell epitopes and determine the CD4+ or CD8+ T cell component response. Additionally, we generate data on the T cell phenotype and measure polyfunctional cytokine secretion by these antigen specific cells. We show candidate peptides able to elicit a T cell response in EBOV survivors and provide inferred human leukocyte antigen (HLA) allele restriction. This data informs on the long-term T cell response to Ebola virus disease and highlights potentially important immunodominant peptides.

scholarly journals Comparative phylogeography of African fruit bats (Chiroptera, Pteropodidae) provide new insights into the outbreak of Ebola virus disease in West Africa, 2014–2016

2016 ◽  
Vol 339 (11-12) ◽  
pp. 517-528 ◽  
Author(s):  
Alexandre Hassanin ◽  
Nicolas Nesi ◽  
Julie Marin ◽  
Blaise Kadjo ◽  
Xavier Pourrut ◽  
...  
Keyword(s):  
West Africa ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
Fruit Bats ◽  
Comparative Phylogeography

scholarly journals Seroprevalence of Ebola virus infection in Bombali District, Sierra Leone

2017 ◽  
Author(s):  
Nadege Goumkwa Mafopa ◽  
Gianluca Russo ◽  
Raoul Emeric Guetiya Wadoum ◽  
Emmanuel Iwerima ◽  
Vincent Batwala ◽  
...  
Keyword(s):  
Immune Response ◽  
Virus Infection ◽  
West Africa ◽  
Sierra Leone ◽  
Ebola Virus ◽  
Virus Disease ◽  
Asymptomatic Infection ◽  
Ebola Virus Disease ◽  
Efficient Immune Response ◽  
Ebola Virus Infection

A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of the 2013-2016 epidemic in West Africa may cause mild or asymptomatic infection in a proportion of cases, possibly due to an efficient immune response.

scholarly journals Ebola virus disease: the ‘Black Swan’ in West Africa

2014 ◽  
Vol 45 (1) ◽  
pp. 2-5 ◽  
Author(s):  
Colin Brown ◽  
Paul Arkell ◽  
Sakib Rokadiya
Keyword(s):  
West Africa ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
Black Swan
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