Effects of three types of bariatric interventions on myocardial infarct size and vascular function in rats with type 2 diabetes mellitus

Life Sciences ◽  
2021 ◽  
pp. 119676
Author(s):  
Oleg V. Kornyushin ◽  
Dmitry L. Sonin ◽  
Alexander S. Polozov ◽  
Vitaly V. Masley ◽  
Maria S. Istomina ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Infarct Size ◽  
Vascular Function ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size

scholarly journals Effects of glucagon-like peptide 1 analogs in combination with insulin on myocardial infarct size in rats with type 2 diabetes mellitus

2018 ◽  
Vol 9 (9) ◽  
pp. 149-156 ◽  
Author(s):  
Vladislav A Zykov ◽  
Taisiia P Tuchina ◽  
Denis A Lebedev ◽  
Irina B Krylova ◽  
Alina Y Babenko ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Infarct Size ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

scholarly journals Effects of the Selective Sodium-Glucose Cotransporter 2 Inhibitor Empagliflozin on Vascular Function and Central Hemodynamics in Patients With Type 2 Diabetes Mellitus

Circulation ◽  
2017 ◽  
Vol 136 (12) ◽  
pp. 1167-1169 ◽  
Author(s):  
Kristina Striepe ◽  
Agnes Jumar ◽  
Christian Ott ◽  
Marina V. Karg ◽  
Markus P. Schneider ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Vascular Function ◽  
Central Hemodynamics ◽  
Sodium Glucose Cotransporter

Effect of Curcuma longa on vascular function in native Tamilians with type 2 diabetes mellitus: A randomized, double‐blind, parallel arm, placebo‐controlled trial

2019 ◽  
Vol 33 (7) ◽  
pp. 1898-1911 ◽  
Author(s):  
Akila Srinivasan ◽  
Sandhiya Selvarajan ◽  
Sadishkumar Kamalanathan ◽  
Tamilarasu Kadhiravan ◽  
Nakka Chandrasekhar Prasanna Lakshmi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Vascular Function ◽  
Curcuma Longa ◽  
Controlled Trial ◽  
Double Blind

scholarly journals Comparison of two sulfonylureas with high and low myocardial KATP channel affinity on myocardial infarct size and metabolism in a rat model of type 2 diabetes

Diabetologia ◽  
2010 ◽  
Vol 54 (2) ◽  
pp. 451-458 ◽  
Author(s):  
S. B. Kristiansen ◽  
B. Løfgren ◽  
J. M. Nielsen ◽  
N. B. Støttrup ◽  
E. S. Buhl ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Infarct Size ◽  
Rat Model ◽  
Katp Channel ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size

scholarly journals IGF-1 is not related to long-term outcome in hyperglycemic acute coronary syndrome patients

2021 ◽  
Vol 18 (6) ◽  
pp. 147916412110474
Author(s):  
Cindya P Iswandi ◽  
Victor J van den Berg ◽  
Suat Simsek ◽  
Daan van Velzen ◽  
Edwin Ten Boekel ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Acute Coronary Syndrome ◽  
Infarct Size ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size ◽  
Coronary Syndrome ◽  
The Relationship

Purpose Insulin-like growth factor-1 (IGF-1) has been associated with both protective and detrimental effects on the development of ischemic heart disease. The relationship between IGF-1 levels and major adverse cardiovascular events (MACE) in acute coronary syndrome (ACS) patients remains unclear. This study aimed to investigate the relationship between IGF-1 admission levels in hyperglycemic ACS patients and: (1) MACE over a 5 years follow-up, (2) type 2 diabetes at discharge, and (3) post-ACS myocardial infarct size and dysfunction. Methods This was a post hoc analysis of the BIOMArCS-2 randomized controlled trial. From July 2008 to February 2012, 276 ACS patients with admission plasma glucose level between 140 and 288 mg/dL were included. Records of the composite of all-cause mortality and recurrent non-fatal myocardial infarction were obtained during 5 years follow-up. Venous blood samples were collected on admission. IGF-1 was measured batchwise after study completion. Oral glucose tolerance test was performed to diagnose type 2 diabetes, whereas infarct size and left ventricular function were assessed by myocardial perfusion scintigraphy (MPS) imaging, 6 weeks post-ACS. Results Cumulative incidence of MACE was 24% at 5 years follow-up. IGF-1 was not independently associated with MACE (HR:1.00 (95%CI:0.99–1.00), p = 0.29). Seventy-eight patients (28%) had type 2 diabetes at discharge, and the highest quartile of IGF-1 levels was associated with the lowest incidence of diabetes (HR:0.40 (95%CI:0.17–0.95), p = 0.037). IGF-1 levels were not associated with post-ACS myocardial infarct size and dysfunction. Conclusions IGF-1 carries potential for predicting type 2 diabetes, rather than long-term cardiovascular outcomes and post-ACS myocardial infarct size and dysfunction, in hyperglycemic ACS patients.

scholarly journals Vitamin E reduces myocardial infarct size in type 2 diabetes

2006 ◽  
Vol 20 (5) ◽  
Author(s):  
Grace Frances Davis‐Gorman ◽  
Raoul Gonzales ◽  
Zoe Cohen ◽  
Paul F. McDonagh
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin E ◽  
Infarct Size ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size
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