The antibacterial mechanism of pterostilbene derived from xinjiang wine grape: A novel apoptosis inducer in Staphyloccocus aureus and Escherichia coli

Inactivation of Gram-negative Escherichia coli and Gram-positive Staphyloccocus aureus in litchi juice by DMDC combined with nisin was individually investigated. A 1.66 log cycles reduction of E. coli and 2.03 log cycles reduction of S. aureus in litchi juice (pH 4.5) added without nisin was achieved as exposed to 150 mg/l DMDC at 30 °C for 1 h, and the inactivation rate of E. coli and S. aureus during initial 1 h was far greater than during the remaining 5 h. As exposed to 150 mg/l DMDC at 30 °C for 1 h, the inactivation of E. coli and S. aureus in the litchi juice showed a trend toward increase with increasing of nisin addition level in the range from 0 to 200 IU/ml. Moreover, DMDC and nisin exhibited a synergistic effect on the inactivation of E. coli and S. aureus in litchi juice, and the inactivation of E. coli and S. aureus in the litchi juice also depends on the temperature of litchi juice, pH value of litchi juice and DMDC concentration when treated with DMDC and nisin. In addition, E. coli showed higher resistance to nisin as comparing with S. aureus. After E. coli and S. aureus in the litchi juice of pH 4.0 were individually treated with 150 mg/l DMDC combined with 200 IU/ml nisin at 30 °C for 1 h, a complete inactivation of S. aureus (6.59 log cycles) was achieved, but only 3.52 log cycles reduction of E. coli was observed.

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Synthesis and Application of Isothiazolinone as Durable Antibacterial

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.331.265 ◽

2011 ◽

Vol 331 ◽

pp. 265-269

Author(s):

De Jia Kong ◽

Zhen Dong Liu ◽

Yan Li Li

Keyword(s):

Escherichia Coli ◽

1H Nmr ◽

Cotton Fabrics ◽

Esi Ms ◽

Antibacterial Performance ◽

Orthogonal Experiments ◽

Washing Durability ◽

Finishing Process ◽

Staphyloccocus Aureus ◽

Reactive Groups

A new antibacterial with two reactive groups was synthesized from isothiazolin-3-one and characterized by 1H-NMR and ESI-MS. Through the orthogonal experiments the optimal finishing process was got, that was bath ratio 1:20, Na2SO4 20 g/L, NaHCO315 g/L, T1:60°C, T2:70°C, t1:10 min, t2:20 min, t3:30 min (as shown in fig.1). The antibacterial evaluations of treated cotton fabrics showed that the antibacterial rates for Escherichia coli and Staphyloccocus aureus were 95.64% and 97.83% respectively, and 88.13% and 90.05% respectively after 30 washing cycles. The results indicated that the treated fabric had excellent antibacterial performance and washing durability.

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Modification of membrane properties and fatty acids biosynthesis-related genes in Escherichia coli and Staphylococcus aureus: Implications for the antibacterial mechanism of naringenin

Biochimica et Biophysica Acta (BBA) - Biomembranes ◽

10.1016/j.bbamem.2017.11.007 ◽

2018 ◽

Vol 1860 (2) ◽

pp. 481-490 ◽

Cited By ~ 23

Author(s):

Lang-Hong Wang ◽

Xin-An Zeng ◽

Man-Sheng Wang ◽

Charles S. Brennan ◽

Deming Gong

Keyword(s):

Escherichia Coli ◽

Fatty Acids ◽

Staphylococcus Aureus ◽

Membrane Properties ◽

Antibacterial Mechanism ◽

And Staphylococcus Aureus

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Colonização por microrganismos em colaboradores da saúde

Enfermagem Brasil ◽

10.33233/eb.v18i2.2115 ◽

2019 ◽

Vol 18 (2) ◽

pp. 213

Author(s):

Bruna Leticia Pereira ◽

Anne Caroline Dias Santos ◽

Johnny Marques Aquino ◽

Gregório Ribeiro De Andrade Neto ◽

Árlen Almeida Duarte De Souza ◽

...

Keyword(s):

Escherichia Coli ◽

Staphylococcus Aureus ◽

Staphyloccocus Aureus ◽

Terapia Intensiva ◽

Acinetobacter Sp

Introdução: As infecções relacionadas ao serviço de saúde são comumente denominadas infecções hospitalares. As Unidades de Terapia Intensivas são unidades onde as infecções hospitalares são frequentes e oferecem alto risco para pacientes, devido à presença de dispositivos invasivos e por estarem imunocomprometidos. Objetivo: Identificar a prevalência dos microrganismos que colonizam os colaboradores da saúde em um Centro de Terapia Intensiva. Métodos: Estudo quantitativo, descritivo e exploratório, realizado a partir da coleta de swabs estéreis das mãos dos profissionais do centro de terapia intensiva adulto, de um hospital da cidade de Montes Claros/MG. Participaram da pesquisa 23 profissionais, correspondendo a 46% da população total do estudo. Resultados: Foram analisadas 23 amostras, verificando o crescimento de um ou mais microrganismos em cada teste. Os microrganismos encontrados nas mãos dos profissionais do centro de terapia intensiva foram: Staphylococcus sp coagulase negativa (47,8%), Staphylococcus Aureus - MRSA (21,7%), Klebsiella pneunoniae (13,0%), Enterobacter sp (13,0%), Acinetobacter sp (8,7%), Escherichia coli (4,3%) e Staphyloccocus aureus (4,3%). Conclusão: Há a necessidade de implementação de políticas de saúde que impactem na padronização e uso criterioso dos antimicrobianos na prática clínica e a adesão dos profissionais às medidas de prevenção e de controle da cadeia epidemiológica.Palavras-chave: desinfecção, infecção hospitalar, unidade de terapia intensiva.

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A preventive antibacterial mechanism: Against enteropathogenic <italic>Escherichia coli</italic> by intracellular protein reaction

Chinese Science Bulletin (Chinese Version) ◽

10.1360/tb-2020-0718 ◽

2020 ◽

Vol 65 (34) ◽

pp. 3851-3853

Author(s):

Tingting Hong ◽

Lin Qiu ◽

Shuwen Zhou ◽

Pengfei Cui ◽

Jianhao Wang ◽

...

Keyword(s):

Escherichia Coli ◽

Antibacterial Mechanism ◽

Intracellular Protein ◽

Protein Reaction

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Étude in vitro des propriétés antioxydante, antiproliférative et antimicrobienne de Salvia clandestina du Maroc

Phytothérapie ◽

10.3166/phyto-2019-0202 ◽

2019 ◽

Author(s):

A. Et-Touys ◽

A. Bouyahya ◽

I. Bourais ◽

N. Dakka ◽

Y. Bakri

Keyword(s):

Escherichia Coli ◽

Staphylococcus Aureus ◽

Listeria Monocytogenes ◽

Staphyloccocus Aureus

L’objectif de cette étude vise l’évaluation in vitro de l’activité antioxydante, antiproliférative et antimicrobienne des extraits organiques Salvia clandestina du Maroc. L’effet antioxydant est estimé par le test de balayage du radical DPPH. L’activité antiproliférative est évaluée sur deux lignées cellulaires cancéreuses en utilisant le test MTT. L’activité antimicrobienne est évaluée contre Escherichia coli, Staphyloccocus aureus et Listeria monocytogenes. L’extrait d’hexane et de dichlorométhane ont montré des capacités antioxydantes à l’IC50 = 118,28 ± 2,108 et 191,36 ± 2,72 μg/ml, respectivement. Alors que l’extrait méthanolique a montré une remarquable activité antiproliférative contre la lignée RD (IC50 = 86,24 μg/ml). Concernant l’activité antimicrobienne, les extraits hexanique et méthanolique sont plus actifs, alors que Staphylococcus aureus s’est montré la plus sensible. Vu les résultats obtenus, Salvia clandestina pourrait être considérée comme une source importante de molécules bioactives. Cependant, d’autres investigations sont nécessaires regardant les principes actifs responsables des effets pharmacologiques obtenus ainsi que l’investigation de l’action antibactérienne et anticancéreuse.

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