Coenzyme Q addition to an n-6 PUFA-rich diet resembles benefits on age-related mitochondrial DNA deletion and oxidative stress of a MUFA-rich diet in rat heart

2010 ◽  
Vol 131 (1) ◽  
pp. 38-47 ◽  
Author(s):  
José L. Quiles ◽  
Reinald Pamplona ◽  
M. Carmen Ramirez-Tortosa ◽  
Alba Naudí ◽  
Manuel Portero-Otin ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Dna ◽  
Rat Heart ◽  
Coenzyme Q ◽  
Mitochondrial Dna Deletion ◽  
Dna Deletion ◽  
Age Related ◽  
And Oxidative Stress

Age-related changes in brain mitochondrial DNA deletion and oxidative stress are differentially modulated by dietary fat type and coenzyme Q10

2011 ◽  
Vol 50 (9) ◽  
pp. 1053-1064 ◽  
Author(s):  
Julio J. Ochoa ◽  
Reinald Pamplona ◽  
M. Carmen Ramirez-Tortosa ◽  
Sergio Granados-Principal ◽  
Patricia Perez-Lopez ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Dna ◽  
Coenzyme Q10 ◽  
Dietary Fat ◽  
Mitochondrial Dna Deletion ◽  
Dna Deletion ◽  
Age Related ◽  
And Oxidative Stress ◽  
Age Related Changes

Mitochondrial DNA Deletion Associated Oxidative Stress and Severe Male Osteoporosis

1999 ◽  
Vol 10 (2) ◽  
pp. 143-149 ◽  
Author(s):  
S. S. Varanasi ◽  
R. M. Francis ◽  
C. E. M. Berger ◽  
S. S. Papiha ◽  
H. K. Datta
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Dna ◽  
Male Osteoporosis ◽  
Mitochondrial Dna Deletion ◽  
Dna Deletion

Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress brain

1998 ◽  
Vol 254 (2) ◽  
pp. 109-112 ◽  
Author(s):  
Yasuhisa Fujibayashi ◽  
Shoko Yamamoto ◽  
Atsuo Waki ◽  
Junji Konishi ◽  
Yoshiharu Yonekura
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Dna ◽  
Mouse Model ◽  
Mitochondrial Dna Deletion ◽  
Dna Deletion ◽  
The Brain

scholarly journals Age-Related Mitochondrial DNA Deletion in Rat Liver Depends on Dietary Fat Unsaturation

2006 ◽  
Vol 61 (2) ◽  
pp. 107-114 ◽  
Author(s):  
José L. Quiles ◽  
Julio J. Ochoa ◽  
M. Carmen Ramirez-Tortosa ◽  
Jesús R. Huertas ◽  
José Mataix
Keyword(s):  
Mitochondrial Dna ◽  
Rat Liver ◽  
Dietary Fat ◽  
Mitochondrial Dna Deletion ◽  
Dna Deletion ◽  
Age Related

Age-related mitochondrial DNA deletion in human heart: Its relationship with cardiovascular diseases

2003 ◽  
Vol 15 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Tomio Arai ◽  
Ken-ichi Nakahara ◽  
Hiroko Matsuoka ◽  
Motoji Sawabe ◽  
Koji Chida ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Cardiovascular Diseases ◽  
Human Heart ◽  
Mitochondrial Dna Deletion ◽  
Dna Deletion ◽  
Age Related

scholarly journals Impact of Polyphenolic-Food on Longevity: An Elixir of Life. An Overview

Antioxidants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 507
Author(s):  
Rosaria Meccariello ◽  
Stefania D’Angelo
Keyword(s):  
Oxidative Stress ◽  
Food Sources ◽  
Preventive Action ◽  
Nutritional Interventions ◽  
Beneficial Effects ◽  
Age Related ◽  
Macromolecular Damage ◽  
And Oxidative Stress

Aging and, particularly, the onset of age-related diseases are associated with tissue dysfunction and macromolecular damage, some of which can be attributed to accumulation of oxidative damage. Recently, growing interest has emerged on the beneficial effects of plant-based diets for the prevention of chronic diseases including obesity, diabetes, and cardiovascular disease. Several studies collectively suggests that the intake of polyphenols and their major food sources may exert beneficial effects on improving insulin resistance and related diabetes risk factors, such as inflammation and oxidative stress. They are the most abundant antioxidants in the diet, and their intake has been associated with a reduced aging in humans. Polyphenolic intake has been shown to be effective at ameliorating several age-related phenotypes, including oxidative stress, inflammation, impaired proteostasis, and cellular senescence, both in vitro and in vivo. In this paper, effects of these phytochemicals (either pure forms or polyphenolic-food) are reviewed and summarized according to affected cellular signaling pathways. Finally, the effectiveness of the anti-aging preventive action of nutritional interventions based on diets rich in polyphenolic food, such as the diets of the Blue zones, are discussed.

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