Global stability analysis of viral infection model with logistic growth rate, general incidence function and cellular immunity

2021 ◽  
Author(s):  
Tohid Kasbi Gharahasanlou ◽  
Vahid Roomi ◽  
Zeynab Hemmatzadeh
Keyword(s):  
Growth Rate ◽  
Stability Analysis ◽  
Viral Infection ◽  
Global Stability ◽  
Cellular Immunity ◽  
Logistic Growth ◽  
Infection Model ◽  
Global Stability Analysis ◽  
Incidence Function ◽  
Viral Infection Model

Global dynamics of hepatitis C viral infection with logistic proliferation

2016 ◽  
Vol 09 (04) ◽  
pp. 1650056
Author(s):  
Sandip Banerjee ◽  
Ram Keval ◽  
Sunita Gakkhar
Keyword(s):  
Mathematical Model ◽  
Hepatitis C Virus ◽  
Stability Analysis ◽  
Hepatitis C ◽  
Viral Infection ◽  
Global Stability ◽  
Geometric Approach ◽  
Global Dynamics ◽  
Viral Dynamics ◽  
Global Stability Analysis

A modified mathematical model of hepatitis C viral dynamics has been presented in this paper, which is described by four coupled ordinary differential equations. The aim of this paper is to perform global stability analysis using geometric approach to stability, based on the higher-order generalization of Bendixson’s criterion. The result is also supported numerically. An important epidemiological issue of eradicating hepatitis C virus has been addressed through the global stability analysis.

scholarly journals Global Stability for a Viral Infection Model with Saturated Incidence Rate

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Huaqin Peng ◽  
Zhiming Guo
Keyword(s):  
Viral Infection ◽  
Global Stability ◽  
Incidence Rate ◽  
Sufficient Conditions ◽  
Basic Reproductive Number ◽  
Reproductive Number ◽  
Infection Model ◽  
Saturated Incidence Rate ◽  
Saturated Incidence ◽  
Viral Infection Model

A viral infection model with saturated incidence rate and viral infection with delay is derived and analyzed; the incidence rate is assumed to be a specific nonlinear formβxv/(1+αv). The existence and uniqueness of equilibrium are proved. The basic reproductive numberR0is given. The model is divided into two cases: with or without delay. In each case, by constructing Lyapunov functionals, necessary and sufficient conditions are given to ensure the global stability of the models.

Global dynamics of an age-structured viral infection model with general incidence function and absorption

2018 ◽  
Vol 11 (05) ◽  
pp. 1850065 ◽  
Author(s):  
Khalid Hattaf ◽  
Yu Yang
Keyword(s):  
Viral Infection ◽  
Infection Model ◽  
Uniform Persistence ◽  
Global Dynamics ◽  
Incidence Function ◽  
Proposed Model ◽  
Viral Particles ◽  
Age Structured ◽  
Well Posed ◽  
Viral Infection Model

In this paper, we propose an age-structured viral infection model with general incidence function that takes account of the loss of viral particles due to their absorption into susceptible cells. The proposed model is described by partial differential and ordinary differential equations. We first show that the model is mathematically and biologically well-posed. Furthermore, the uniform persistence and the global behavior of the model are investigated. Moreover, the age-structured models and results presented in many previous studies are improved and generalized.

scholarly journals Global stability of a distributed delayed viral model with general incidence rate

2018 ◽  
Vol 16 (1) ◽  
pp. 1374-1389
Author(s):  
Eric Ávila-Vales ◽  
Abraham Canul-Pech ◽  
Erika Rivero-Esquivel
Keyword(s):  
Immune Response ◽  
Viral Infection ◽  
Global Stability ◽  
Numerical Simulations ◽  
Incidence Rate ◽  
Existence And Uniqueness ◽  
Lyapunov Functional ◽  
Infection Model ◽  
General Incidence Rate ◽  
Viral Infection Model

AbstractIn this paper, we discussed a infinitely distributed delayed viral infection model with nonlinear immune response and general incidence rate. We proved the existence and uniqueness of the equilibria. By using the Lyapunov functional and LaSalle invariance principle, we obtained the conditions of global stabilities of the infection-free equilibrium, the immune-exhausted equilibrium and the endemic equilibrium. Numerical simulations are given to verify the analytical results.

scholarly journals Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent Diffusion

Complexity ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-20 ◽  
Author(s):  
Xiaosong Tang ◽  
Zhiwei Wang ◽  
Jianping Yang
Keyword(s):  
Viral Infection ◽  
Competitive Exclusion ◽  
Neumann Boundary ◽  
Infection Model ◽  
Threshold Dynamics ◽  
Single Strain ◽  
Density Dependent ◽  
Incidence Function ◽  
Infection Models ◽  
Viral Infection Model

In this paper, we investigate single-strain and multistrain viral infection models with general incidence function and density-dependent diffusion subject to the homogeneous Neumann boundary conditions. For the single-strain viral infection model, by using the linearization method and constructing appropriate Lyapunov functionals, we obtain that the global threshold dynamics of the model is determined by the reproductive numbers for viral infection ℛ0. For the multistrain viral infection model, we have discussed the competitive exclusion problem. If the reproduction number ℛi for strain i is maximal and larger than one, the steady state Ei corresponding to the strain i is globally stable. Thus, competitive exclusion happens and all other strains die out except strain i. Meanwhile, we can prove that the single-strain and multistrain viral infection models are well posed. Furthermore, numerical simulations are also carried out to illustrate the theoretical results, which is seldom seen in the relevant known literatures.

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