Negative correlation between pressure-pain threshold and serum S100β levels in pre-and postmenopausal women: a cross-sectional study

Maturitas ◽  
2019 ◽  
Vol 124 ◽  
pp. 170
Author(s):  
Fernanda Vargas Ferreira ◽  
Charles Francisco Ferreira ◽  
Mona Lúcia Dall’Agno ◽  
Jéssica Zandoná ◽  
Joana Zanotti ◽  
...  
Author(s):  
Tania López Hernández ◽  
Marina Caparó Ferré ◽  
Sílvia Giné Martí ◽  
Isabel Salvat Salvat

Back pain in children is a reality and various factors are involved in its etiology. The study’s aim was to analyze the relationship between the use and type of backpack and pain in children. An analytical observational cross-sectional study was conducted among 123 schoolchildren between 8–10 years. Data on the participants’ weight and height and their backpacks were collected, as well as the way of travel to school and their physical activity during the week. The results indicated that all backpacks were large because the backpack’s height is longer than torso length. Participants who studied in a traditional educational system (62.60%) carried backpacks that exceeded 10% of their body weight. Additionally, 31.7% of the students presented pain. There is no significant correlation between the weight or type of backpack and the pressure pain threshold collected from shoulders muscles. Participants who carried backpacks heavier than 10% of their body weight did not have more musculoskeletal pain or a lower pressure pain threshold than the others, although they did report greater fatigue. All these topics should be debated considering the student’s social environment and the backpack’s discomfort to the children, even though no relationship was found between musculoskeletal pain and backpack weight.


2019 ◽  
Vol 57 (1) ◽  
pp. 61-67
Author(s):  
Nicoleta Dumitru ◽  
Mara Carsote ◽  
Andra Cocolos ◽  
Eugenia Petrova ◽  
Maria Olaru ◽  
...  

Abstract Introduction. Current studies support the implication of metabolic changes associated with type 2 diabetes in altering bone metabolism, structure and resistance. Objective. We conducted a cross-sectional study on postmenopausal women aimed to analyze the differences in metabolic and bone profile in patients with and without type 2 diabetes Methods. We analyzed the metabolic and bone profile in postmenopausal women with and without type 2 diabetes (T2DM). Clinical, metabolic, hormonal parameters, along with lumbar, hip and femoral bone mineral density (BMD) and trabecular bone score (TBS) were evaluated. Results. 56 women with T2DM(63.57±8.97 years) and 83 non-T2DM (60.21±8.77 years) were included. T2DM patients presented a higher value of body mass index (BMI) and BMD vs. control group (p = 0.001; p = 0.03-lumbar level, p = 0.07-femoral neck and p = 0.001-total hip). Also, BMI correlated positively with lumbar-BMD and glycated hemoglobin (HbA1c) (r = 0.348, p = 0.01; r = 0.269, p = 0.04), correlation maintained even after age and estimated glomerular filtration rate (eGFR) adjustment (r = 0.383, p = 0.005; r = 0.237, p = 0.08). Diabetic patients recorded lower levels of 25(OH)D(p = 0.05), bone markers (p ≤ 0.05) and TBS(p = 0.07). For the entire patient group we found a negative correlation between HbA1c level and bone markers: r = -0.358, p = 0.0005-osteocalcin, r = -0.40, p = 0.0005-P1NP, r = -0.258, p = 0.005-crosslaps. Conclusions. Our results indicate the presence of altered bone microarchitecture in T2DZ patients according to the TBS score, combined with lower levels of bone markers, with a statistically significant negative correlation between HbA1c level and bone markers.


2017 ◽  
Vol 23 (3) ◽  
pp. 172 ◽  
Author(s):  
Mamun Ibn Bashar ◽  
Kawsar Ahmed ◽  
Muhammad Shahin Uddin ◽  
Farzana Ahmed ◽  
Abdullah-Al Emran ◽  
...  

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