Relationship of Body Mass Index With Total Mortality, Cardiovascular Mortality, and Myocardial Infarction After Coronary Revascularization: Evidence From a Meta-analysis

2014 ◽  
Vol 89 (8) ◽  
pp. 1080-1100 ◽  
Author(s):  
Abhishek Sharma ◽  
Ajay Vallakati ◽  
Andrew J. Einstein ◽  
Carl J. Lavie ◽  
Armin Arbab-Zadeh ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Body Mass Index ◽  
Body Mass ◽  
Cardiovascular Mortality ◽  
Coronary Revascularization ◽  
Meta Analysis ◽  
Total Mortality ◽  
Relationship Of

scholarly journals Migraine and cardiovascular disease

2011 ◽  
Vol 69 (1) ◽  
pp. 122-129 ◽  
Author(s):  
Marcelo E. Bigal
Keyword(s):  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Risk Factor ◽  
Diagnostic Criteria ◽  
Epidemiological Study ◽  
Cardiovascular Mortality ◽  
Coronary Revascularization ◽  
Meta Analysis ◽  
Established Risk Factor ◽  
The Brain

Migraine, especially migraine with aura is an established risk factor for ischemic lesions of the brain. Recent evidence has also linked migraine with and without aura to a broader range of ischemic vascular disorders including angina, myocardial infarction, coronary revascularization, claudication and cardiovascular mortality. The topic is therefore of considerable interest. Accordingly, herein we review the association between migraine and cardiovascular disease. We start by briefly presenting diagnostic criteria for migraine and revising its pathophysiology. We follow by summarizing the evidence on the topic. We then briefly present the results of a recent meta-analysis. We close by highlighting results of a large epidemiological study conducted after the publication of the meta-analysis.

Abstract P383: Relationship of Body Mass Index With Total Mortality, Cardiac Mortality and Risk of Hospitalization in Patients With Chronic Heart Failure

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Abhishek Sharma ◽  
Carl J Lavie ◽  
Jeffrey S Borer ◽  
Ajay Vallakati ◽  
Francisco Lopez-Jimenez ◽  
...  
Keyword(s):  
Heart Failure ◽  
Body Mass Index ◽  
Chronic Heart Failure ◽  
Body Mass ◽  
Total Mortality ◽  
Forest Plot ◽  
Cardiac Mortality ◽  
Severely Obese ◽  
Low Bmi ◽  
Relationship Of

Objective: To investigate the relationship of body mass index (BMI) with total mortality, cardiac mortality and risk of hospitalization in patients with chronic heart failure (HF). Methods: A systematic search of studies published between 1966 to January 31, 2014 was conducted using Pub Med, CINAHL, Cochrane CENTRAL and the Web of Science databases. Studies reporting rate of total mortality, cardiac mortality and risk of hospitalization in patients with HF in various BMI categories [<20 kg/m2 (low); 20-24.9 kg/m2 (normal reference); 25-29.9 kg/m2 (overweight); 30-34.9 kg/m2 (obese); >=35 kg/m2 (severely obese)] were identified. Event rates were compared using a forest plot of relative risk using a random effects model assuming inter-study heterogeneity. Results: Two study authors independently reviewed the 124 articles and identified 6 for final analyses (N=22807). After mean follow up of 2.85 years, the risk of total mortality, cardiovascular (CV) mortality and of hospitalization was highest among patients with low BMI (RR 1.27 [95% CI 1.17 - 1.37]; 1.20 [95% CI 1.01 -1.43]; 1.19 [95% CI 1.09 - 1.30] respectively). Risk of cardiac mortality and hospitalization was lowest in overweight patients (RR0.79 [95% CI 0.70-0.90] and 0.92 [95% CI 0.86-0.97] respectively). Increasing degree of obesity failed to achieve a statistically significant effect on CV mortality (0.82 [0.64-1.05] and 0.71 [0.50-1.01] for obese and severely obese, respectively) and on hospitalization (0.99 [0.92-1.07] and 1.28 [0.88-1.87] for obese and severely obese, respectively) Conclusion: Risk of total mortality, cardiac mortality and hospitalization was highest among chronic HF patients who were underweight as defined by low BMI, whereas risk of cardiac mortality and hospitalization was lowest in the overweight. Further prospective studies are needed to investigate this association and apparent “overweight paradox” and explore potential underlying mechanisms for this association.

scholarly journals Meta-Analysis of the Relation of Body Mass Index to All-Cause and Cardiovascular Mortality and Hospitalization in Patients With Chronic Heart Failure

2015 ◽  
Vol 115 (10) ◽  
pp. 1428-1434 ◽  
Author(s):  
Abhishek Sharma ◽  
Carl J. Lavie ◽  
Jeffrey S. Borer ◽  
Ajay Vallakati ◽  
Sunny Goel ◽  
...  
Keyword(s):  
Heart Failure ◽  
Body Mass Index ◽  
Chronic Heart Failure ◽  
Body Mass ◽  
Cardiovascular Mortality ◽  
Meta Analysis

scholarly journals Association between body mass index and 1-year outcome after acute myocardial infarction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D.W Kim
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Body Mass Index ◽  
Confidence Interval ◽  
Body Mass ◽  
Cardiac Death ◽  
Funding Source ◽  
Group Iii ◽  
End Point ◽  
Group I

Abstract Background Beneficial effects of overweight and obesity on mortality after acute myocardial infarction (AMI) have been described as “Body Mass Index (BMI) paradox”. However, the effects of BMI is still on debate. We analyzed the association between BMI and 1-year major cardiocerebrovascular events (MACCE) after AMI. Methods and findings Among 13,104 AMI patients registered in an Institute of Health in Korea between November 2011 and December 2015, 10,568 patients who eligible for this study were classified into 3 groups according to BMI (Group I; &lt;22 kg/m2, 22 ≤ Group II &lt;26 kg/m2, Group III; ≥26 kg/m2). The primary end point was a composite of cardiac death (CD), myocardial infarction (MI), target vessel revascularization (TVR), and cerebrovascular events at 1 year. Over the median follow-up of 12 months, the composite of primary end point occurred more frequently in the Group I patients than in the Group III patients (primary endpoint: adjusted hazard ratio [aHR], 1.290; 95% confidence interval [CI] 1.024 to 1.625, p=0.031). Especially, cardiac death in MACCE components played a major role in this effect (aHR, 1.548; 95% confidence interval [CI] 1.128 to 2.124, p=0.007). Conclusions Higher BMI appeared to be good prognostic factor on 1-year MACCE after AMI. This result suggests that higher BMI or obesity might confer a protective advantage over the life-quality after AMI. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): Research of Korea Centers for Disease Control and Prevention and the Korea Health Technology R&D Project, Ministry of Health & Welfare (HI13C1527), Republic of Korea.

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