The Combyn™ ECG: Adding haemodynamic and fluid leads for the ECG. Part II: Prediction of total body water (TBW), extracellular fluid (ECF), ECF overload, fat mass (FM) and “dry” appendicular muscle mass (AppMM)

2017 ◽  
Vol 44 ◽  
pp. 44-52 ◽  
Author(s):  
Falko Skrabal ◽  
Georg P. Pichler ◽  
Mathias Penatzer ◽  
Johannes Steinbichl ◽  
Anna-Katharina Hanserl ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Fat Mass ◽  
Total Body Water ◽  
Extracellular Fluid ◽  
Body Water ◽  
Total Body ◽  
Appendicular Muscle Mass

scholarly journals The Effect of Tibolone on Fat Mass, Fat-Free Mass, and Total Body Water in Postmenopausal Women

Endocrinology ◽  
2001 ◽  
Vol 142 (11) ◽  
pp. 4813-4817 ◽  
Author(s):  
Ingrid B. Meeuwsen ◽  
Monique M. Samson ◽  
Sijmen A. Duursma ◽  
Harald J. Verhaar
Keyword(s):  
Postmenopausal Women ◽  
Fat Mass ◽  
Total Body Water ◽  
Body Water ◽  
Fat Free Mass ◽  
Total Body

Time course and magnitude of changes in total body water, extracellular fluid volume, intracellular fluid volume and plasma volume during submaximal exercise and recovery in horses

2004 ◽  
Vol 1 (2) ◽  
pp. 131-139 ◽  
Author(s):  
Michael I Lindinger ◽  
Gloria McKeen ◽  
Gayle L Ecker
Keyword(s):  
Plasma Volume ◽  
Total Body Water ◽  
Time Course ◽  
Extracellular Fluid ◽  
Submaximal Exercise ◽  
Body Water ◽  
Fluid Volume ◽  
Extracellular Fluid Volume ◽  
Intracellular Fluid ◽  
Total Body

AbstractThe purpose of the present study was to determine the time course and magnitude of changes in extracellular and intracellular fluid volumes in relation to changes in total body water during prolonged submaximal exercise and recovery in horses. Seven horses were physically conditioned over a 2-month period and trained to trot on a treadmill. Total body water (TBW), extracellular fluid volume (ECFV) and plasma volume (PV) were measured at rest using indicator dilution techniques (D2O, thiocyanate and Evans Blue, respectively). Changes in TBW were assessed from measures of body mass, and changes in PV and ECFV were calculated from changes in plasma protein concentration. Horses exercised by trotting on a treadmill for 75–120 min incurred a 4.2% decrease in TBW. During exercise, the entire decrease in TBW (mean±standard error: 12.8±2.0 l at end of exercise) could be attributed to the decrease in ECFV (12.0±2.4 l at end of exercise), such that there was no change in intracellular fluid volume (ICFV; 0.9±2.4 l at end of exercise). PV decreased from 22.0±0.5 l at rest to 19.8±0.3 l at end of exercise and remained depressed (18–19 l) during the first 2 h of recovery. Recovery of fluid volumes after exercise was slow, and characterized by a further transient loss of ECFV (first 30 min of recovery) and a sustained increase in ICFV (between 0.5 and 3.5 h of recovery). Recovery of fluid volumes was complete by 13 h post exercise. It is concluded that prolonged submaximal exercise in horses favours net loss of fluid from the extracellular fluid compartment.

scholarly journals Extracellular fluid and total body water changes in neonates undergoing extracorporeal membrane oxygenation

1992 ◽  
Vol 27 (8) ◽  
pp. 1003-1008 ◽  
Author(s):  
Harry L. Anderson ◽  
Arnold G. Coran ◽  
Robert A. Drongowski ◽  
Hyun J. Ha ◽  
Robert H. Bartlett
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Total Body Water ◽  
Extracellular Fluid ◽  
Body Water ◽  
Membrane Oxygenation ◽  
Total Body

The Ratio of Extracellular Fluid to Total Body Water and Technique Survival in Peritoneal Dialysis Patients

2004 ◽  
Vol 24 (4) ◽  
pp. 353-358 ◽  
Author(s):  
Colin H. Jones ◽  
Charles G. Newstead
Keyword(s):  
Peritoneal Dialysis ◽  
Total Body Water ◽  
Extracellular Fluid ◽  
Residual Renal Function ◽  
Body Water ◽  
C Reactive Protein ◽  
Dialysis Patients ◽  
Technique Survival ◽  
Reactive Protein ◽  
Total Body

Background Patients receiving peritoneal dialysis experience a high technique failure rate and are often overhydrated. We examined whether an increased extracellular fluid volume (VECF) as a proportion of the total body water (VTBW) predicted technique survival (TS) in a prevalent patient cohort. Methods The VECF and VTBW were estimated by multiple-frequency bioelectric impedance in 59 prevalent peritoneal dialysis patients (median time on dialysis 14 months). Demographic, biochemical (albumin, C-reactive protein, and ferritin), and anthropometric data, forearm muscle strength, nutritional score by three-point Subjective Global Assessment, residual renal function, dialysate-to-plasma (D/P) creatinine ratio, total weekly Kt/V urea, total creatinine clearance, normalized protein equivalent of nitrogen appearance, and midarm muscle circumference were also assessed. Technique survival was determined at 3 years, and significant predictors of TS were sought. Results In patient groups defined by falling above or below the median value for each parameter, only residual renal function ( p = 0.002), 24-hour ultrafiltrate volume ( p = 0.02), and VECF / VTBW ratio ( p = 0.05) were significant predictors of TS. Subjects with a higher than median VECF / VTBW ratio had a 3-year TS of 46%, compared to 78% in subjects with a lower than median value. In multivariate analysis, systolic blood pressure and VECF / VTBW ratio (both p < 0.05) were significant predictors of TS. C-reactive protein approached significance. Conclusion Increased ratio of extracellular fluid volume to total body water is associated with decreased TS in peritoneal dialysis.

scholarly journals Skeletal Muscle Mass and Extracellular Water/Total Body Water Independently Predict Phase Angle Percentile in Young Men

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1169-1169
Author(s):  
Jacob Gray ◽  
Tay Kennedy
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Phase Angle ◽  
Total Body Water ◽  
Skeletal Muscle Mass ◽  
Body Water ◽  
Hydration Status ◽  
State University ◽  
Extracellular Water ◽  
Total Body

Abstract Objectives Phase angle, derived from bioelectrical impedance analysis (BIA), is used to describe both cellular and overall health. Many of the variables measured using BIA vary based on the hydration status of the individual. The ratio between extracellular water/total body water is commonly measured in BIA, and can be used as a measure of individual hydration. This pilot study explores the relationship between individual hydration status and phase angle and other BIA measurements. Methods Male college students (n = 57) from Oklahoma State University-Stillwater were recruited through an email messaging campaign. The participants answered an online Qualtrics demographic survey; height (±0.1 cm), blood pressure, and weight were taken. The Seca Medical Body Composition Analyzer mBCA 514 was used to conduct the BIA. Variable mean, standard deviations, and frequencies were calculated using SPSS version 25. Pearson correlation analysis and regression analysis were conducted. Significance was set at &lt;.05. Results Participants characteristics included: age (m = 21.7 ± 1.3 years), 54% BMI &lt;25, 39% blood pressure &lt;120/80, and 63% white/7% Native American. Mean % body fat was 20.28 ± 8.76, and skeletal muscle was 32.223 kg ± 4.432 and visceral fat was 2.01 liters ± 2.11.Phase angle percentile ranged from 1% to 99% (m = 62.0% ± 31.4) and extracellular water/total body water ratio (ECW/TBW) ranged from 35.7 to 41.6 (m = 39.32 ± 1.35). Phase angle percentile was positively correlated with skeletal muscle mass (r = 0.503, P = 0.000) and negatively correlated with ECW/TBW (r = −0.659, P = 0.000), but not with other BIA variables. These two variables significantly predicted phase angle percentile (r2 = 0.817, P = 0.000). The standardized β was −0.762 (P = 0.000) for ECW/TBW and 0.627 (P = 0.000) for skeletal muscle mass. Conclusions The association of ECW/TBW on phase angle percentile suggest further investigation of the impact of water on this indicator of health is warranted. An investigation with a method of modulating ECW/TBW would be a logical next step in understanding this relationship. Funding Sources Funding was provided by the Lew Wentz Foundation, and the Nutritional Sciences Department at Oklahoma State University.

scholarly journals Gender Differences in rhGH-Induced Changes in Body Composition in GH-Deficient Adults

2001 ◽  
Vol 86 (9) ◽  
pp. 4161-4165 ◽  
Author(s):  
Jan P. T. Span ◽  
Gerlach F. F. M. Pieters ◽  
Fred G. J. Sweep ◽  
Ad R. M. M. Hermus ◽  
Anthony G. H. Smals
Keyword(s):  
Gender Differences ◽  
Body Composition ◽  
Fat Mass ◽  
Total Body Water ◽  
Body Water ◽  
Fat Free Mass ◽  
Time Intervals ◽  
Rhgh Therapy ◽  
Igf I ◽  
Total Body

In GH-deficient adults, rhGH has pronounced effects on total body water, fat free mass, and fat mass. Recently, we observed a gender difference in IGF-I responsivity to rhGH that was sex steroid dependent. The aim of the present study was to assess the effect of rhGH therapy on body composition parameters with due attention to the gender differences in biological responsiveness to rhGH. Forty-four women [36.9 ± 11.9 yr (mean ± sd)] and 33 men (37.2 ± 13.8 yr) with GH deficiency were studied every 6 months during 2 yr. The treatment goal was to achieve IGF-I levels within the age-adjusted normal range. Total body water, fat free mass, and fat mass were measured by bioimpedantiometry. To reach the treatment goal, the daily rhGH dose (IU/kg/d) had to be significantly higher in women than in men at all time intervals. During rhGH therapy, total body water and fat free mass increased significantly in both men and women (P ≤ 0.01 by ANOVA), but changes were more pronounced in men. Fat mass decreased during rhGH treatment and reached its nadir at 6 months, which was more pronounced in men than in women (P = 0.02 by ANOVA). After the initial decrease, fat mass increased again and reached baseline values after 2 yr of treatment. In both men and women, the total body water and fat free mass increases were closely related to the IGF-I increments (P &lt; 0.001 by Pearson’s correlation test). The decrease in fat mass correlated significantly with the increase in IGF-I in men (r = −0.89, P &lt; 0.001), not in women. Confirming our earlier data, IGF-I responsivity to rhGH was significantly higher in men than in women at all time intervals (P &lt; 0.01 by ANOVA). Total body water and fat free mass responsivities were also higher in men than in women (P &lt; 0.01 by ANOVA). In conclusion, gender differences in IGF-I responsivities to rhGH are accompanied by gender differences in the extent of body composition changes to rhGH. Probably because of these gender differences in IGF-I responsivity, the increases of total body water and fat free mass to rhGH replacement were greater in men than in women. Remarkably, however, in men, only total body water and fat free mass responses relative to changes in IGF-I increased during the 2 yr of rhGH therapy (P= 0.02 and 0.01, respectively, by ANOVA). In our opinion, this phenomenon might be explained by the increasing target organ sensitivity to IGF-I over time.

Some biochemical and physiological features of normal monkeys (Macaca radiata)

1963 ◽  
Vol 18 (6) ◽  
pp. 1231-1233 ◽  
Author(s):  
S. G. Srikantia ◽  
C. Gopalan
Keyword(s):  
Total Body Water ◽  
Body Fluid ◽  
Extracellular Fluid ◽  
Body Water ◽  
Fluid Volume ◽  
Extracellular Fluid Volume ◽  
Sodium Thiocyanate ◽  
Macaca Radiata ◽  
Hematological Indices ◽  
Total Body

Determinations of body-fluid spaces with antipyrine for total-body water and sodium thiocyanate for extracellular fluid volume, hematological indices, and several serum constituents in about 500 Macaca radiata monkeys revealed that most of the values obtained were very similar to values obtained in man. body fluid spaces; hematology Submitted on April 22, 1963

Comparison of techniques to estimate total body skeletal muscle mass in people of different age groups

1999 ◽  
Vol 277 (3) ◽  
pp. E489-E495 ◽  
Author(s):  
D. N. Proctor ◽  
P. C. O’Brien ◽  
E. J. Atkinson ◽  
K. S. Nair
Keyword(s):  
Muscle Mass ◽  
Body Mass ◽  
Total Body Water ◽  
Body Water ◽  
Body Protein ◽  
Creatinine Excretion ◽  
Urinary Creatinine ◽  
Protein Mass ◽  
Total Body ◽  
Urinary Creatinine Excretion

An estimate of total body muscle mass with dual-energy X-ray absorptiometry (DXA; appendicular muscle mass divided by 0.75) was compared with 24-h urinary creatinine excretion in 59 healthy men and women [20–30 yr (younger), 45–59 yr (middle age), and 60–79 yr (older)] who stayed in a clinical research center for 5 days. Total body water (2H2O dilution), fat (underwater weighing), bone mineral (DXA), and total body protein mass (based on a 4-compartment model) were also measured. Muscle mass estimates by DXA and creatinine were highly correlated ( r = 0.80). However, stepwise multiple regression indicated that a significant amount of additional between-subject variability in DXA-based muscle mass estimates could be explained by total body water. Creatinine excretion, knee extensor strength, and total body protein mass all decreased with age, suggesting a decline in muscle cell mass with aging. However, DXA-based muscle mass and measures of nonfat body mass (i.e., lean body mass by2H2O and fat-free body mass by underwater weighing) did not change with age. These results indicate that DXA and urinary creatinine excretion give different results regarding the decline in total body muscle mass with aging. The factor(s) responsible for the apparent underestimate of age-related sarcopenia by DXA remain to be fully defined, but changes in body water may be an important contributor.

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