scholarly journals Deep learning-based solvability of underdetermined inverse problems in medical imaging

2021 ◽  
Vol 69 ◽  
pp. 101967
Author(s):  
Chang Min Hyun ◽  
Seong Hyeon Baek ◽  
Mingyu Lee ◽  
Sung Min Lee ◽  
Jin Keun Seo
Keyword(s):  
Deep Learning ◽  
Medical Imaging ◽  
Inverse Problems

scholarly journals Data augmentation for computed tomography angiography via synthetic image generation and neural domain adaptation

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Malte Seemann ◽  
Lennart Bargsten ◽  
Alexander Schlaefer
Keyword(s):  
Computed Tomography ◽  
Neural Networks ◽  
Deep Learning ◽  
Medical Imaging ◽  
Computed Tomography Angiography ◽  
Data Augmentation ◽  
Domain Adaptation ◽  
Synthetic Image ◽  
Wide Range ◽  
The Impact

AbstractDeep learning methods produce promising results when applied to a wide range of medical imaging tasks, including segmentation of artery lumen in computed tomography angiography (CTA) data. However, to perform sufficiently, neural networks have to be trained on large amounts of high quality annotated data. In the realm of medical imaging, annotations are not only quite scarce but also often not entirely reliable. To tackle both challenges, we developed a two-step approach for generating realistic synthetic CTA data for the purpose of data augmentation. In the first step moderately realistic images are generated in a purely numerical fashion. In the second step these images are improved by applying neural domain adaptation. We evaluated the impact of synthetic data on lumen segmentation via convolutional neural networks (CNNs) by comparing resulting performances. Improvements of up to 5% in terms of Dice coefficient and 20% for Hausdorff distance represent a proof of concept that the proposed augmentation procedure can be used to enhance deep learning-based segmentation for artery lumen in CTA images.

Diagnosing breast cancer tumors using stacked ensemble model

2021 ◽  
pp. 1-9
Author(s):  
Ahmet Haşim Yurttakal ◽  
Hasan Erbay ◽  
Türkan İkizceli ◽  
Seyhan Karaçavuş ◽  
Cenker Biçer
Keyword(s):  
Breast Cancer ◽  
Deep Learning ◽  
Medical Imaging ◽  
Early Stage ◽  
False Negative ◽  
Gradient Boosting ◽  
Physical Sign ◽  
Ensemble Model ◽  
Learning Methods ◽  
Dce Mri

Breast cancer is the most common cancer that progresses from cells in the breast tissue among women. Early-stage detection could reduce death rates significantly, and the detection-stage determines the treatment process. Mammography is utilized to discover breast cancer at an early stage prior to any physical sign. However, mammography might return false-negative, in which case, if it is suspected that lesions might have cancer of chance greater than two percent, a biopsy is recommended. About 30 percent of biopsies result in malignancy that means the rate of unnecessary biopsies is high. So to reduce unnecessary biopsies, recently, due to its excellent capability in soft tissue imaging, Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) has been utilized to detect breast cancer. Nowadays, DCE-MRI is a highly recommended method not only to identify breast cancer but also to monitor its development, and to interpret tumorous regions. However, in addition to being a time-consuming process, the accuracy depends on radiologists’ experience. Radiomic data, on the other hand, are used in medical imaging and have the potential to extract disease characteristics that can not be seen by the naked eye. Radiomics are hard-coded features and provide crucial information about the disease where it is imaged. Conversely, deep learning methods like convolutional neural networks(CNNs) learn features automatically from the dataset. Especially in medical imaging, CNNs’ performance is better than compared to hard-coded features-based methods. However, combining the power of these two types of features increases accuracy significantly, which is especially critical in medicine. Herein, a stacked ensemble of gradient boosting and deep learning models were developed to classify breast tumors using DCE-MRI images. The model makes use of radiomics acquired from pixel information in breast DCE-MRI images. Prior to train the model, radiomics had been applied to the factor analysis to refine the feature set and eliminate unuseful features. The performance metrics, as well as the comparisons to some well-known machine learning methods, state the ensemble model outperforms its counterparts. The ensembled model’s accuracy is 94.87% and its AUC value is 0.9728. The recall and precision are 1.0 and 0.9130, respectively, whereas F1-score is 0.9545.

scholarly journals End-to-end privacy preserving deep learning on multi-institutional medical imaging

2021 ◽  
Author(s):  
Georgios Kaissis ◽  
Alexander Ziller ◽  
Jonathan Passerat-Palmbach ◽  
Théo Ryffel ◽  
Dmitrii Usynin ◽  
...  
Keyword(s):  
Deep Learning ◽  
Medical Imaging ◽  
Privacy Preserving ◽  
End To End

scholarly journals Deep learning-enabled medical computer vision

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Andre Esteva ◽  
Katherine Chou ◽  
Serena Yeung ◽  
Nikhil Naik ◽  
Ali Madani ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Neural Networks ◽  
Computer Vision ◽  
Deep Learning ◽  
Medical Imaging ◽  
Real World ◽  
Recent Progress ◽  
Medical Applications ◽  
Modern Computer ◽  
Medical Computer

AbstractA decade of unprecedented progress in artificial intelligence (AI) has demonstrated the potential for many fields—including medicine—to benefit from the insights that AI techniques can extract from data. Here we survey recent progress in the development of modern computer vision techniques—powered by deep learning—for medical applications, focusing on medical imaging, medical video, and clinical deployment. We start by briefly summarizing a decade of progress in convolutional neural networks, including the vision tasks they enable, in the context of healthcare. Next, we discuss several example medical imaging applications that stand to benefit—including cardiology, pathology, dermatology, ophthalmology–and propose new avenues for continued work. We then expand into general medical video, highlighting ways in which clinical workflows can integrate computer vision to enhance care. Finally, we discuss the challenges and hurdles required for real-world clinical deployment of these technologies.

Hierarchical and Multi-resolution Neuron Network Computing for Complex Inverse Problems-An Approach Based on Brain-inspired Computing and Learning Method

2021 ◽  
Vol 01 ◽  
Author(s):  
Mingyong Zhou
Keyword(s):  
Deep Learning ◽  
Inverse Problems ◽  
Radar Imaging ◽  
Network Computing ◽  
Neuron Network ◽  
Impedance Tomography ◽  
General Complex ◽  
Mathematical Algorithms ◽  
Ill Posed ◽  
Regular Operators

Background: Complex inverse problems such as Radar Imaging and CT/EIT imaging are well investigated in mathematical algorithms with various regularization methods. However it is difficult to obtain stable inverse solutions with fast convergence and high accuracy at the same time due to the ill-posed property and non-linear property. Objective: In this paper, we propose a hierarchical and multi-resolution scalable method from both algorithm perspective and hardware perspective to achieve fast and accurate solu-tions for inverse problems by taking radar and EIT imaging as examples. Method: We present an extension of discussion on neuromorphic computing as brain-inspired computing method and the learning/training algorithm to design a series of problem specific AI “brains” (with different memristive values) to solve a general complex ill-posed inverse problems that are traditionally solved by mathematical regular operators. We design a hierarchical and multi-resolution scalable method and an algorithm framework to train AI deep learning neuron network and map into the memristive circuit so that the memristive val-ues are optimally obtained. We propose FPGA as an emulation implementation for neuro-morphic circuit as well. Result: We compared the methodology between our approach and traditional regulariza-tion method. In particular we use Electrical Impedance Tomography (EIT) and Radar imaging as typical examples to compare how to design an AI deep learning neuron network architec-tures to solve inverse problems. Conclusion: With EIT imaging as a typical example, we show that any moderate complex inverse problem, as long as it can be described as combinational problem, AI deep learning neuron network is a practical alternative approach to try to solve the inverse problems with any given expected resolution accuracy, as long as the neuron network width is large enough and computational power is strong enough for all combination samples training purpose.

Deep Learning In Medical Imaging And Drug Design

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Surayya Ado Bala ◽  
Shri Ojha Kant ◽  
Adamu Garba Yakasai
Keyword(s):  
Deep Learning ◽  
Medical Imaging ◽  
Drug Design ◽  
Therapy Monitoring ◽  
Surrogate Endpoint ◽  
Cellular Level ◽  
Response To Therapy ◽  
Response To Treatment ◽  
Design Decision ◽  
Medical Diagnostic

Over the last decade, deep learning (DL) methods have been extremely successful and widely used in almost every domain. Researchers are now focusing on the convergence of medical imaging and drug design using deep learning to revolutionize medical diagnostic and improvement in the monitoring from response to therapy. DL a new machine learning paradigm that focuses on learning with deep hierarchical models of data. Medical imaging has transformed healthcare science, it was thought of as a diagnostic tool for disease, but now it is also used in drug design. Advances in medical imaging technology have enabled scientists to detect events at the cellular level. The role of medical imaging in drug design includes identification of likely responders, detection, diagnosis, evaluation, therapy monitoring, and follow-up. A qualitative medical image is transformed into a quantitative biomarker or surrogate endpoint useful in drug design decision-making. For this, a parameter needs to be identified that characterizes the disease baseline and its subsequent response to treatment. The result is a quantifiable improvement in healthcare quality in most therapeutic areas, resulting in improvements in quality and duration of life. This paper provides an overview of recent studies on applying the deep learning method in medical imaging and drug design. We briefly discuss the fields related to the history of deep learning, medical imaging, and drug design.

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