scholarly journals Data augmentation for computed tomography angiography via synthetic image generation and neural domain adaptation

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Malte Seemann ◽  
Lennart Bargsten ◽  
Alexander Schlaefer
Keyword(s):  
Computed Tomography ◽  
Neural Networks ◽  
Deep Learning ◽  
Medical Imaging ◽  
Computed Tomography Angiography ◽  
Data Augmentation ◽  
Domain Adaptation ◽  
Synthetic Image ◽  
Wide Range ◽  
The Impact

AbstractDeep learning methods produce promising results when applied to a wide range of medical imaging tasks, including segmentation of artery lumen in computed tomography angiography (CTA) data. However, to perform sufficiently, neural networks have to be trained on large amounts of high quality annotated data. In the realm of medical imaging, annotations are not only quite scarce but also often not entirely reliable. To tackle both challenges, we developed a two-step approach for generating realistic synthetic CTA data for the purpose of data augmentation. In the first step moderately realistic images are generated in a purely numerical fashion. In the second step these images are improved by applying neural domain adaptation. We evaluated the impact of synthetic data on lumen segmentation via convolutional neural networks (CNNs) by comparing resulting performances. Improvements of up to 5% in terms of Dice coefficient and 20% for Hausdorff distance represent a proof of concept that the proposed augmentation procedure can be used to enhance deep learning-based segmentation for artery lumen in CTA images.

scholarly journals Hyperparameter Optimization and Regularization on Fashion-MNIST Classification

2019 ◽  
Vol 8 (2) ◽  
pp. 3713-3719
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Data Augmentation ◽  
Network Models ◽  
Classification Problems ◽  
Regularization Techniques ◽  
Cropping Rotation ◽  
The Impact ◽  
Deep Learning Model ◽  
Learning In Computer Vision

Nowadays the most exciting technology breakthrough has been the rise of the deep learning. In computer vision Convolutional Neural Networks (CNN or ConvNet) are the default deep learning model used for image classification problems. In these deep network models, feature extraction is figure out by itself and these models tend to perform well with huge amount of samples. Herein we explore the impact of various Hyper-Parameter Optimization (HPO) methods and regularization techniques with deep neural networks on FashionMNIST (F-MNIST) dataset which is proposed by Zalando Research. We have proposed deep ConvNet architectures with Data Augmentation and explore the impact of this by configuring the hyperparameters and regularization methods. As deep learning requires a lots of data, the insufficiency of image samples can be expand through various data augmentation methods like Cropping, Rotation, Flipping, and Shifting. The experimental results show impressive results on this new benchmarking dataset F-MNIST

Levenshtein Augmentation Improves Performance of SMILES Based Deep-Learning Synthesis Prediction

2020 ◽  
Author(s):  
Dean Sumner ◽  
Jiazhen He ◽  
Amol Thakkar ◽  
Ola Engkvist ◽  
Esben Jannik Bjerrum
Keyword(s):  
Neural Networks ◽  
Pattern Recognition ◽  
Deep Learning ◽  
Recurrent Neural Networks ◽  
Data Augmentation ◽  
State Of The Art ◽  
Sequence Similarity ◽  
Learning Models ◽  
Underlying Network

<p>SMILES randomization, a form of data augmentation, has previously been shown to increase the performance of deep learning models compared to non-augmented baselines. Here, we propose a novel data augmentation method we call “Levenshtein augmentation” which considers local SMILES sub-sequence similarity between reactants and their respective products when creating training pairs. The performance of Levenshtein augmentation was tested using two state of the art models - transformer and sequence-to-sequence based recurrent neural networks with attention. Levenshtein augmentation demonstrated an increase performance over non-augmented, and conventionally SMILES randomization augmented data when used for training of baseline models. Furthermore, Levenshtein augmentation seemingly results in what we define as <i>attentional gain </i>– an enhancement in the pattern recognition capabilities of the underlying network to molecular motifs.</p>

scholarly journals Deep learning for end-to-end kidney cancer diagnosis on multi-phase abdominal computed tomography

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Kwang-Hyun Uhm ◽  
Seung-Won Jung ◽  
Moon Hyung Choi ◽  
Hong-Kyu Shin ◽  
Jae-Ik Yoo ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Deep Learning ◽  
Kidney Cancer ◽  
Renal Tumor ◽  
Renal Tumors ◽  
Abdominal Computed Tomography ◽  
Wide Range ◽  
End To End ◽  
Multi Phase ◽  
Histologic Subtypes

AbstractIn 2020, it is estimated that 73,750 kidney cancer cases were diagnosed, and 14,830 people died from cancer in the United States. Preoperative multi-phase abdominal computed tomography (CT) is often used for detecting lesions and classifying histologic subtypes of renal tumor to avoid unnecessary biopsy or surgery. However, there exists inter-observer variability due to subtle differences in the imaging features of tumor subtypes, which makes decisions on treatment challenging. While deep learning has been recently applied to the automated diagnosis of renal tumor, classification of a wide range of subtype classes has not been sufficiently studied yet. In this paper, we propose an end-to-end deep learning model for the differential diagnosis of five major histologic subtypes of renal tumors including both benign and malignant tumors on multi-phase CT. Our model is a unified framework to simultaneously identify lesions and classify subtypes for the diagnosis without manual intervention. We trained and tested the model using CT data from 308 patients who underwent nephrectomy for renal tumors. The model achieved an area under the curve (AUC) of 0.889, and outperformed radiologists for most subtypes. We further validated the model on an independent dataset of 184 patients from The Cancer Imaging Archive (TCIA). The AUC for this dataset was 0.855, and the model performed comparably to the radiologists. These results indicate that our model can achieve similar or better diagnostic performance than radiologists in differentiating a wide range of renal tumors on multi-phase CT.

scholarly journals Deep learning-enabled medical computer vision

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Andre Esteva ◽  
Katherine Chou ◽  
Serena Yeung ◽  
Nikhil Naik ◽  
Ali Madani ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Neural Networks ◽  
Computer Vision ◽  
Deep Learning ◽  
Medical Imaging ◽  
Real World ◽  
Recent Progress ◽  
Medical Applications ◽  
Modern Computer ◽  
Medical Computer

AbstractA decade of unprecedented progress in artificial intelligence (AI) has demonstrated the potential for many fields—including medicine—to benefit from the insights that AI techniques can extract from data. Here we survey recent progress in the development of modern computer vision techniques—powered by deep learning—for medical applications, focusing on medical imaging, medical video, and clinical deployment. We start by briefly summarizing a decade of progress in convolutional neural networks, including the vision tasks they enable, in the context of healthcare. Next, we discuss several example medical imaging applications that stand to benefit—including cardiology, pathology, dermatology, ophthalmology–and propose new avenues for continued work. We then expand into general medical video, highlighting ways in which clinical workflows can integrate computer vision to enhance care. Finally, we discuss the challenges and hurdles required for real-world clinical deployment of these technologies.

scholarly journals Comparative Analysis on Deep Learning Approaches for Heavy-Vehicle Detection based on Data Augmentation and Transfer-Learning techniques

2021 ◽  
Vol 13 (3) ◽  
pp. 809-820
Author(s):  
V. Sowmya ◽  
R. Radha
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Real Time ◽  
Transfer Learning ◽  
Convolutional Neural Networks ◽  
Traffic Management ◽  
Data Augmentation ◽  
Vehicle Detection ◽  
Heavy Vehicles ◽  
Detection And Recognition

Vehicle detection and recognition require demanding advanced computational intelligence and resources in a real-time traffic surveillance system for effective traffic management of all possible contingencies. One of the focus areas of deep intelligent systems is to facilitate vehicle detection and recognition techniques for robust traffic management of heavy vehicles. The following are such sophisticated mechanisms: Support Vector Machine (SVM), Convolutional Neural Networks (CNN), Regional Convolutional Neural Networks (R-CNN), You Only Look Once (YOLO) model, etcetera. Accordingly, it is pivotal to choose the precise algorithm for vehicle detection and recognition, which also addresses the real-time environment. In this study, a comparison of deep learning algorithms, such as the Faster R-CNN, YOLOv2, YOLOv3, and YOLOv4, are focused on diverse aspects of the features. Two entities for transport heavy vehicles, the buses and trucks, constitute detection and recognition elements in this proposed work. The mechanics of data augmentation and transfer-learning is implemented in the model; to build, execute, train, and test for detection and recognition to avoid over-fitting and improve speed and accuracy. Extensive empirical evaluation is conducted on two standard datasets such as COCO and PASCAL VOC 2007. Finally, comparative results and analyses are presented based on real-time.

scholarly journals Computed Tomography Angiography under Deep Learning in the Treatment of Atherosclerosis with Rapamycin

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Fuguang Ji ◽  
Shuai Zhou ◽  
Zhangshuan Bi
Keyword(s):  
Computed Tomography ◽  
Deep Learning ◽  
Computed Tomography Angiography ◽  
Atherosclerotic Lesion ◽  
Region Of Interest ◽  
Left Ventricular ◽  
Dice Similarity Coefficient ◽  
Imaging Features ◽  
Lesion Area ◽  
Imaging Characteristics

The clinical characteristics and vascular computed tomography (CT) imaging characteristics of patients were explored so as to assist clinicians in diagnosing patients with atherosclerosis. 316 patients with atherosclerosis who were hospitalized for emergency treatment were treated with rapamycin (RAPA) in the hospital. A group of manually delineated left ventricular myocardia (LVM) on the patient’s coronary computed tomography angiography (CCTA) were selected as the region of interest for imaging features extracted. The CCTA images of 80% of patients were randomly selected for training, and those of 20% of patients were used for verification. The correlation matrix method was used to remove redundant image omics features under different correlation thresholds. In the validation set, CCTA diagnostic parameters were about 40 times higher than the manually segmented data. The average dice similarity coefficient was 91.6%. The proposed method also produced a very small centroid distance (mean 1.058 mm, standard deviation 1.245 mm) and volume difference (mean 1.640), with a segmentation time of about 1.45 ± 0.51 s, compared to about 744.8 ± 117.49 s for physician manual segmentation. Therefore, the deep learning model effectively segmented the atherosclerotic lesion area, measured and assisted the diagnosis of future atherosclerosis clinical cases, improved medical efficiency, and accurately identified the patient’s lesion area. It had great application potential in helping diagnosis and curative effect analysis of atherosclerosis.

scholarly journals AI-driven deep CNN approach for multi-label pathology classification using chest X-Rays

2021 ◽  
Vol 7 ◽  
pp. e495
Author(s):  
Saleh Albahli ◽  
Hafiz Tayyab Rauf ◽  
Abdulelah Algosaibi ◽  
Valentina Emilia Balas
Keyword(s):  
Neural Networks ◽  
Data Augmentation ◽  
State Of The Art ◽  
Synthetic Data ◽  
X Rays ◽  
Deep Convolutional Neural Networks ◽  
Current State ◽  
Pathology Classification ◽  
Wide Range ◽  
Multi Class Classification

Artificial intelligence (AI) has played a significant role in image analysis and feature extraction, applied to detect and diagnose a wide range of chest-related diseases. Although several researchers have used current state-of-the-art approaches and have produced impressive chest-related clinical outcomes, specific techniques may not contribute many advantages if one type of disease is detected without the rest being identified. Those who tried to identify multiple chest-related diseases were ineffective due to insufficient data and the available data not being balanced. This research provides a significant contribution to the healthcare industry and the research community by proposing a synthetic data augmentation in three deep Convolutional Neural Networks (CNNs) architectures for the detection of 14 chest-related diseases. The employed models are DenseNet121, InceptionResNetV2, and ResNet152V2; after training and validation, an average ROC-AUC score of 0.80 was obtained competitive as compared to the previous models that were trained for multi-class classification to detect anomalies in x-ray images. This research illustrates how the proposed model practices state-of-the-art deep neural networks to classify 14 chest-related diseases with better accuracy.

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