Down-regulation of lincRNA-EPS regulates apoptosis and autophagy in BCG-infected RAW264.7 macrophages via JNK/MAPK signaling pathway

2020 ◽  
Vol 77 ◽  
pp. 104077 ◽  
Author(s):  
Zunqiong Ke ◽  
Jianwu Lu ◽  
Jietao Zhu ◽  
Zhongwei Yang ◽  
Zhixiong Jin ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Mapk Signaling ◽  
Mapk Signaling Pathway ◽  
Down Regulation ◽  
Raw264.7 Macrophages

scholarly journals Down-regulation of RPS9 Inhibits Osteosarcoma Cell Growth through Inactivation of MAPK Signaling Pathway

2017 ◽  
Vol 8 (14) ◽  
pp. 2720-2728 ◽  
Author(s):  
Dong-dong Cheng ◽  
Bin Zhu ◽  
Shi-jie Li ◽  
Ting Yuan ◽  
Qing-cheng Yang ◽  
...  
Keyword(s):  
Cell Growth ◽  
Signaling Pathway ◽  
Mapk Signaling ◽  
Mapk Signaling Pathway ◽  
Osteosarcoma Cell ◽  
Down Regulation

scholarly journals Down-regulation of HIV-1 infection by inhibition of the MAPK signaling pathway

2011 ◽  
Vol 26 (2) ◽  
pp. 114-122 ◽  
Author(s):  
Jian Gong ◽  
Xi-hui Shen ◽  
Chao Chen ◽  
Hui Qiu ◽  
Rong-ge Yang
Keyword(s):  
Signaling Pathway ◽  
Mapk Signaling ◽  
Mapk Signaling Pathway ◽  
Down Regulation ◽  
Hiv 1

scholarly journals Astragalus polysaccharide enhances the immune function of RAW264.7 macrophages via the NF‑κB p65/MAPK signaling pathway

2020 ◽  
Vol 21 (1) ◽  
pp. 1-1
Author(s):  
Shibin Feng ◽  
Hongyan Ding ◽  
Leihong Liu ◽  
Chenglu Peng ◽  
Yingying Huang ◽  
...  
Keyword(s):  
Immune Function ◽  
Signaling Pathway ◽  
Mapk Signaling ◽  
Mapk Signaling Pathway ◽  
Nf Kappa B ◽  
Raw264.7 Macrophages

scholarly journals SLC34A2 Up-regulation And SLC4A4 Down-regulation Correlates With Invasion, Metastasis, And The MAPK Signaling Pathway In Papillary Thyroid Carcinomas

2021 ◽  
Vol 12 (18) ◽  
pp. 5439-5453
Author(s):  
Fengyan Huang ◽  
Haitao Wang ◽  
Juan Xiao ◽  
Chunchun Shao ◽  
Yong Zhou ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Mapk Signaling ◽  
Mapk Signaling Pathway ◽  
Papillary Thyroid ◽  
Down Regulation ◽  
Thyroid Carcinomas

MAPK: A Key Player in the Development and Progression of Stroke

2020 ◽  
Vol 19 (4) ◽  
pp. 248-256
Author(s):  
Yangmin Zheng ◽  
Ziping Han ◽  
Haiping Zhao ◽  
Yumin Luo
Keyword(s):  
Ischemic Stroke ◽  
Signaling Pathway ◽  
Complex Disease ◽  
Therapeutic Targets ◽  
Cell Types ◽  
Mapk Signaling ◽  
Mapk Signaling Pathway ◽  
Effective Prevention ◽  
Prevention And Treatment ◽  
Different Cell Types

Conclusion: Stroke is a complex disease caused by genetic and environmental factors, and its etiological mechanism has not been fully clarified yet, which brings great challenges to its effective prevention and treatment. MAPK signaling pathway regulates gene expression of eukaryotic cells and basic cellular processes such as cell proliferation, differentiation, migration, metabolism and apoptosis, which are considered as therapeutic targets for many diseases. Up to now, mounting evidence has shown that MAPK signaling pathway is involved in the pathogenesis and development of ischemic stroke. However, the upstream kinase and downstream kinase of MAPK signaling pathway are complex and the influencing factors are numerous, the exact role of MAPK signaling pathway in the pathogenesis of ischemic stroke has not been fully elucidated. MAPK signaling molecules in different cell types in the brain respond variously after stroke injury, therefore, the present review article is committed to summarizing the pathological process of different cell types participating in stroke, discussed the mechanism of MAPK participating in stroke. We further elucidated that MAPK signaling pathway molecules can be used as therapeutic targets for stroke, thus promoting the prevention and treatment of stroke.

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