Is Toxoplasma gondii a potential risk factor for Alzheimer's disease? A systematic review and meta-analysis

2019 ◽  
Vol 137 ◽  
pp. 103751 ◽  
Author(s):  
Tooran Nayeri Chegeni ◽  
Shahabeddin Sarvi ◽  
Mahmood Moosazadeh ◽  
Mehdi Sharif ◽  
Sargis A. Aghayan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Toxoplasma Gondii ◽  
Potential Risk ◽  
Meta Analysis ◽  
Potential Risk Factor

scholarly journals Association of Toxoplasmosis with suicide: A systematic review and meta-analysis

2019 ◽  
Author(s):  
Eissa Soleymani ◽  
Fariba Faizi ◽  
Rashid Heidarimoghadam ◽  
Lotfollah Davoodi ◽  
Younes Mohammadi
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Publication Bias ◽  
Potential Risk ◽  
Meta Analysis ◽  
Random Effect ◽  
Potential Risk Factor ◽  
Analysis Phase ◽  
Analysis Methods ◽  
And Control

Abstract Background findings on association of Toxoplasmosis and suicide is contradictory. This paper aimed to resolve this uncertainty with help of Meta-analysis. Methods using keywords include “Toxoplasmosis” and “suicide” and the relayed synonyms in international databases such as ISI, Medline and Scopus, we found the relevant studies. The eligible studies included into Meta-analysis phase. Random effect approach was used to combine the results. Results out of 150 initial studies, 16 were included into meta-analysis. Odds of suicide in person with toxoplasmosis was 47% (OR: 1.47, 95%CI; 1.20 to 1.79) higher than of that without toxoplasmosis. Test for publication bias was not statistically significant, which indicate absence of likely publication bias. Conclusion This study confirm which toxoplasmosis is a potential risk factor for suicide. To reduce cases of suicide attributable to Toxoplasmosis, it deserving the measures to prevent and control of transmission of toxoplasmosis should be taken.

Early-life Pb exposure as a potential risk factor for Alzheimer’s disease: are there hazards for the Mexican population?

2019 ◽  
Vol 24 (8) ◽  
pp. 1285-1303 ◽  
Author(s):  
Miguel Chin-Chan ◽  
Luis Cobos-Puc ◽  
Isabel Alvarado-Cruz ◽  
Melike Bayar ◽  
Maria Ermolaeva
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Potential Risk ◽  
Early Life ◽  
Mexican Population ◽  
Potential Risk Factor ◽  
Pb Exposure

Drugs with anticholinergic properties: a potential risk factor for psychosis onset in Alzheimer's disease?

2009 ◽  
Vol 8 (5) ◽  
pp. 549-557 ◽  
Author(s):  
Iacopo Cancelli ◽  
Massimiliano Beltrame ◽  
Lucio D'Anna ◽  
Gian Luigi Gigli ◽  
Mariarosaria Valente
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Potential Risk ◽  
Potential Risk Factor

Prior blood transfusion as a potential risk factor for Alzheimer's disease

Neurology ◽  
1994 ◽  
Vol 44 (6) ◽  
pp. 1159-1159 ◽  
Author(s):  
N. I.L.J. Bohnen ◽  
M. A. Warner ◽  
E. Kokmen ◽  
C. M. Beard ◽  
L. T. Kurland
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Blood Transfusion ◽  
Potential Risk ◽  
Potential Risk Factor

Periodontitis: a potential risk factor for Alzheimer's disease

BDJ ◽  
2015 ◽  
Vol 218 (1) ◽  
pp. 29-34 ◽  
Author(s):  
T. L. Cerajewska ◽  
M. Davies ◽  
N. X. West
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Potential Risk ◽  
Potential Risk Factor

scholarly journals Periodontitis: a potential risk factor for Alzheimer's disease

BDJ Team ◽  
2016 ◽  
Vol 3 (4) ◽  
Author(s):  
T. L. Cerajewska ◽  
M. Davies ◽  
N. X. West
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Potential Risk ◽  
Potential Risk Factor

scholarly journals Head Injury as a Risk Factor for Dementia and Alzheimer’s Disease: A Systematic Review and Meta-Analysis of 32 Observational Studies

PLoS ONE ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. e0169650 ◽  
Author(s):  
Yanjun Li ◽  
Yongming Li ◽  
Xiaotao Li ◽  
Shuang Zhang ◽  
Jincheng Zhao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Head Injury ◽  
Observational Studies ◽  
Meta Analysis

scholarly journals Sex Differences in Depression as a Risk Factor for Alzheimer’s Disease: A Systematic Review

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Emily A Underwood ◽  
Heather P Davidson ◽  
Amber B Azam ◽  
Mary C Tierney
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sex Differences ◽  
Risk Factor ◽  
Meta Analysis ◽  
Qualitative Synthesis ◽  
Moderating Factors ◽  
Cochrane Reviews ◽  
Underlying Mechanisms

Abstract Background and Objectives Depression is an important risk factor for Alzheimer’s disease (AD) but little is known about the mechanisms of this association. Given sex differences in both AD and depression, we sought to conduct a systematic review and meta-analysis to examine whether there are sex differences in their association, as this may improve understanding of underlying mechanisms. Research Design and Methods MEDLINE, PsycINFO, and Cochrane Reviews were searched for observational studies including both sexes and examining the association between history of depression and AD. Results Forty studies, including 62,729 women and 47,342 men, were identified. Meta-analysis was not possible because only 3 studies provided sufficient data. Seven studies provided information about the influence of sex for a qualitative synthesis. Two found an association in men only, 2 in women only, and 3 reported no sex differences. The 2 studies finding an association in women only were unique in that they had the shortest follow-up periods, and were the only clinic-based studies. Discussion and Implications The findings of our systematic review show that there are important methodological differences among the few studies providing data on the influence of sex on depression as a risk factor for AD. Had all 40 studies provided sex-segregated data, these methodological differences and their impact on sex effects could have been examined quantitatively. We encourage researchers to report these data, as well as potential moderating factors, so that the role of sex differences can be better understood.

Sign in / Sign up

Export Citation Format

Share Document